Endometriosis

List of Contributors, viii Preface, xiii List of Abbreviations, xv Part 1: History, Epidemiology, and Economics 1 History of Endometriosis: A 20th-Century Disease, 3 Ivo Brosens and Giuseppe Benagiano 2 Endometriosis: Epidemiology, and Etiological Factors, 19 Fabio Parazzini, Paolo Vercellini and Claudio Pelucchi 3 Economic Perspective on Diagnosis and Treatment of Endometriosis, 27 Steven Simoens and Thomas M. D'Hooghe Part 2: Pathogenesis 4 Pathogenesis: Development of the Female Genital Tract, 35 Jolande A. Land and Johannes L.H. Evers 5 Theories on the Pathogenesis of Endometriosis, 42 Annemiek W. Nap 6 Understanding the Pathogenesis of Endometriosis: Gene Mapping Studies, 54 Jodie N. Painter, Krina T. Zondervan and Grant W. Montgomery 7 Pathogenesis: Epigenetics, 65 Sun-Wei Guo Part 3: Disease Characterization 8 Endometriosis: Disease Classification and Behavior, 81 G. David Adamson 9 Peritoneal, Ovarian, and Rectovaginal Endometriosis are Three Different Entities, 92 Jacques Donnez, Olivier Donnez, Jean-Christophe Lousse and Jean Squifflet 10 Extra-abdominal Endometriosis, 108 Antonio Bobbio, Diane Damotte, Anne Gompel and Marco Alifano Part 4: Biological Basis and Pathophysiology of Endometriosis 11 Biology of Eutopic and Ectopic Endometrium in Women with Endometriosis, 117 Petra A. B. Klemmt and Anna Starzinski-Powitz 12 Stem Cells in Endometriosis, 130 Caroline E. Gargett, Hirotaka Masuda and Gareth C. Weston 13 Role of Steroid Hormones: Estrogen and Endometriosis, 140 Elke Winterhager 14 Role of Steroid Hormones: Progesterone Signaling, 145 Shirin Khanjani, Marwa K. Al-Sabbagh, Luca Fusi and Jan J. Brosens 15 Early Origins of Endometriosis: Role of Endocrine Disrupting Chemicals, 153 Germaine M. Buck Louis 16 Signaling Pathways in Endometriosis (Eutopic/Ectopic), 164 J. Julie Kim and Xunqin Yin 17 MicroRNAs in Endometriosis, 173 M. Louise Hull and Cristin G. Print 18 HOX Genes and Endometriosis, 184 Jennifer L. Kulp, Hakan Cakmak and Hugh S. Taylor 19 Angiogenesis and Endometriosis, 190 Patrick. G. Groothuis 20 Uterine Peristalsis and the Development of Endometriosis and Adenomyosis, 200 Gerhard Leyendecker and Ludwig Wildt 21 Pelvic Mechanisms Involved in the Pathophysiology of Pain in Endometriosis, 212 Ian S. Fraser, Natsuko Tokushige, Alison J. Hey-Cunningham, Marina Berbic and Cecilia H. M. Ng 22 Neuroendocrine Aspects of Endometriosis-Associated Pain, 230 Pamela Stratton and Karen J. Berkley 23 Pathophysiology of Infertility in Endometriosis, 240 Bruce A. Lessey and Steven L. Young 24 Inflammation and Endometriosis, 255 Daniela Hornung and Ursula von Wussow Part 5: Models of Endometriosis 25 Models of Endometriosis: In vitro and In vivo Models, 265 Ruth Grümmer 26 Models of Endometriosis: Animal Models I - Rodent-based Chimeric Models, 270 Kaylon L. Bruner-Tran, Melinda E. McConaha and Kevin G. Osteen 27 Models of Endometriosis: Animal Models II - Non-human Primates, 285 Asgerally T. Fazleabas Part 6: Diagnosis of Endometriosis 28 Surgical Historical Overview, 295 Ayman Al-Talib and Togas Tulandi 29 Diagnosis of Endometriosis: Imaging, 299 Gerard A. J. Dunselman and Regina G. H. Beets-Tan 30 Diagnosis of Endometriosis: Biomarkers, 309 Beata E. Seeber and Kurt T. Barnhart 31 Diagnosis of Endometriosis: Proteomics, 324 Andrew N. Stephens, Luk J. F. Rombauts and Lois A. Salamonsen 32 Diagnosis of Endometriosis: Transcriptomics, 336 Richard O. Burney and Linda C. Giudice Part 7: Medical Therapies for Pain 33 Medical Therapies: Randomized Controlled Trials/Traditional Medical Therapies, 343 Neil P. Johnson 34 Medical Therapies: Progestins, 351 Andrew Horne and Hilary O. D. Critchley 35 Medical Therapies: Aromatase Inhibitors, 357 Serdar E. Bulun, Erkut Attar, Bilgin Gurates, You-Hong Chen, Hideki Tokunaga, Diana Monsivais and Mary Ellen Pavone 36 Medical Therapies: Statins, 366 Anna Sokalska and Antoni J. Duleba Part 8: Surgical Therapies for Pain 37 Surgical Therapies: Principles and Triage in Endometriosis, 387 Alan Lam, Tommaso Bignardi and Su-Yen Khong 38 Surgical Therapies: Peritoneal Endometriosis Surgery, 396 Michael P. Diamond and Valerie I. Shavell 39 Surgical Therapies: Pouch of Douglas and Uterovaginal Pouch Resection for Endometriosis, 402 Maurício S. Abrão, Sérgio Podgaec and Luiz Flávio Cordeiro Fernandes 40 Surgical Therapies: Randomized Controlled Trials in Endometriosis, 410 Jason Abbott 41 Surgical Therapies: Rectal/Bowel Endometriosis, 419 Jim Tsaltas 42 Surgical Therapies: Ureteric Dissection and Urological Endometriosis, 426 Anna Rosamilia and Caroline Dowling 43 Surgical Therapies: Robotics and Endometriosis, 438 Camran Nezhat, Arathi Veeraswamy and Chandhana Paka Part 9: Infertility and Endometriosis 44 Medical Therapy of Endometriosis: Subfertility, 449 Johannes L. H. Evers 45 Infertility Therapies: The Role of Surgery, 455 Oswald Petrucco and David L. Healy 46 Infertility Therapies: The Role of Assisted Reproductive Technologies, 462 Kimberly Moon, Jeris Cox and Alan DeCherney 47 Ovarian Endometrioma: Surgery and Fertility Preservation, 473 Luk J. F. Rombauts Part 10: Associated Disorders 48 Endometriosis and Autoimmunity, 485 Srinu Pathivada and Thomas D'Hooghe 49 Endometriosis and Cancer: Epidemiology, 501 Paola Viganò, Edgardo Somigliana, Fabio Parazzini and Paolo Vercellini 50 Molecular Mechanisms Underlying Endometriosis and Endometriosis-Related Cancers, 512 Daniela Dinulescu 51 Pregnancy and Obstetric Outcomes in Women with Endometriosis, 519 Henrik Falconer 52 Sexuality in Endometriosis, 524 Brigitte Leeners 53 Psychosomatic Aspects, 533 Brigitte Leeners 54 Endometriosis in the Adolescent Patient, 548 Claire Templeman 55 Fertility Preservation in Patients with Endometrioma, 555 Jennifer Hirshfeld-Cytron, Candace Tingen and Teresa K. Woodruff 56 Eye to the Future: Research, Diagnostics, and Therapeutics, 560 Peter A.W. Rogers and Gareth C. Weston Index, 565 The color plate section can be found facing p. 78