Cholestasis
Proceedings of the International Meeting on Cholestasis and Related Disorders, Florence, Italy, 23-26 March 1994
Elsevier (Publisher)
Published in March 1994
Book
Hardback
400 pages
978-0-444-81638-2 (ISBN)
Description
This work contains contributions dedicated to intracellular mechanisms leading to cholestasis. Less importance is placed upon the structural damage to bile ductules, and increasing importance is attributed to the plasma membrane in order to explain altered uptake and secretion of bile salts. Several new techniques provide support for both old and new theories, especially in experimental models. The book will be of great value to doctors of medicine, specifically hepatologists, contributing to the understanding of mechanisms and the prevention of several cholestatic syndromes, and thereby promoting enthusiasms and research in this important field of liver disease.
This work contains contributions dedicated to intracellular mechanisms leading to cholestasis. Less importance is placed upon the structural damage to bile ductules, and increasing importance is attributed to the plasma membrane in order to explain altered uptake and secretion of bile salts. Several new techniques provide support for both old and new theories, especially in experimental models. The book will be of great value to doctors of medicine, specifically hepatologists, contributing to the understanding of mechanisms and the prevention of several cholestatic syndromes, and thereby promoting enthusiasms and research in this important field of liver disease.
This work contains contributions dedicated to intracellular mechanisms leading to cholestasis. Less importance is placed upon the structural damage to bile ductules, and increasing importance is attributed to the plasma membrane in order to explain altered uptake and secretion of bile salts. Several new techniques provide support for both old and new theories, especially in experimental models. The book will be of great value to doctors of medicine, specifically hepatologists, contributing to the understanding of mechanisms and the prevention of several cholestatic syndromes, and thereby promoting enthusiasms and research in this important field of liver disease.
More details
Series
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Elsevier Science & Technology
Target group
Professional and scholarly
Illustrations
indexes
Dimensions
Height: 230 mm
Weight
1026 gr
ISBN-13
978-0-444-81638-2 (9780444816382)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Persons
Editor
Tufts University School of Medicine, Boston, Massachusetts, USA
Royal Free Hampstead NHS Trust, London
University of Barcelona, Spain
Content
Part 1 Pathophysiology of bile secretion: cholestasis - definition and classification of the major clinical forms, S. Sherlock; the bile secretory apparatus, V.J. Desmet; regulation of bile secretion, S. Erlinger; effects of bile acids and other amphipathic anions on bile flow and biliary lipid secretion, A.F. Hofmann; molecular mechanisms of bile acid transport in hepatocytes, P.J. Meier; the role of vesicle transport and exocytosis in bile formation and cholestasis, J.L. Boyer; cholesterol secretion in bile, M. Bertolotti et al; biliary epithelial cells - biochemical and cytoskeletal characteristics, M. Parola et al. Part 2 Mechanisms of intrahepatic cholestasis: morphological aspects of cholestasis, L. Landmann et al; transhepatic transport, bile secretion and cholestasis mechanisms, I.M. Arias; cholestasis and fibrinogenesis, M. Pinzani et al; drug-induced cholestasis, A.M. Jezequel et al; etiopathogenesis of primary sclerosing cholangitis, R.H. Wiesner; recent insights into the immunopathology of primary biliary cirrhosis, F.B. Bianchi et al. Part 3 Pathophysiological and clinical aspects of cholestasis: impact of cholestasis on hepatic function - retention of cholephiles and their potential targets, J. Reichen et al; immunological syndromes in cholestatic liver diseases, P.A. Berg and R. Klein; lipids and lipoproteins in cholestatic liver disease, D.S. Harry and N. McIntyre; plasma membrane abnormalities in chronic liver disease, G. Laffi et al; renal impairment in chronic liver diseases with and without cholestasis, P. Gentilini et al; renal glomerular involvement in patients with liver disease, K.Z. Casey and H.E. Abboud; pattern of bile acids in cholestasis, A. Stiehl; cholestasis - pathogenetic role and therapeutic action of bile acids, H. Fromm. Part 4 Treatment of cholestatic syndromes: medical treatment of primary biliary cirrhosis, R. Poupon and R.E. Poupon; treatment for hepatocellular cholestatic liver diseases, M. Podda et al; treatment of pruritus of chronic cholestasis, J. Rodes and A. Parees; transmethylation in liver diseases, J.D. Finkelstein; bile acid therapy in gallstones and after liver transplantation, L. Barbara et al; lithotripsy of gallstones, G. Paumgartner; diagnosis and treatment of osteodystrophy in cholestatic liver diseases, M.R. Biagini et al. Part 5 Diagnosis and surgical approach to cholestatic syndromes: diagnosis of cholestatic syndromes - imaging techniques, L. Gandolfi et al; ERCP and endoscopic sphincterotomy in laparoscopic cholecystectomy, A. Morelli and L. Santucci. (Part Contents).