Gene Transfer and Therapy in the Nervous System
Published on 15. December 2011
Book
Paperback/Softback
XIX, 211 pages
978-3-642-84844-5 (ISBN)
Description
Gene transfer technology is a powerful tool for increasing our understandingof brain functions. It is also the basis of gene therapy, which is now technically possible for the correction of many human diseases, including several disorders of the nervous (and muscular) system such as Alzheimer's disease, Parkinson's disease, and dystrophy. This volume,which contains the proceedings of a symposium of the Fondation Ipsen, provides a unique view of the state of the art on different transgenes, vectors, target cells, and clinical applications related to the nervous system.
More details
Series
Edition
Softcover reprint of the original 1st ed. 1992
Language
English
Place of publication
Berlin
Germany
Publishing group
Springer Berlin
Target group
Professional and scholarly
Research
Illustrations
33 s/w Abbildungen
XIX, 211 p. 33 illus.
Dimensions
Height: 242 mm
Width: 170 mm
Thickness: 13 mm
Weight
405 gr
ISBN-13
978-3-642-84844-5 (9783642848445)
DOI
10.1007/978-3-642-84842-1
Schweitzer Classification
Other editions
Additional editions
Fred H. Gage
Gene Transfer and Therapy in the Nervous System
Book
10/1992
Springer
€85.55
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Content
Somatic Cell Gene Therapy.- Delivery of Nerve Growth Factor Within the Rat Brain Using Genetically Modified Cells.- A Potential Approach to Gene Therapy of Cancer.- Phenotypic Plasticity and Neural Grafting.- The Sympathoadrenal Progenitor of the Neural Crest: Basic Biology and Therapeutic Potential.- Lineage, Migration, and Phenotype in Avian Optic Tectum: Analysis with Recombinant Retroviral Vectors.- Immortal Mammalian Neuronal Stem Cells Differentiate after Implantation into the Developing Brain.- Establishment of Clonal Cell Lines for the Study of Neural Function and Dysfunction.- Resistance of SOD-Transgenic Mice to Oxidative Stress.- Gene Transfer into the Nervous System using Recombinant Herpes Virus Vectors.- Development of Herpes Simplex Virus as a Gene Transfer Vector for the Central Nervous System.- Dystrophin mRNA Processing in the Canine Homologue of Duchenne Muscular Dystrophy: An Authentic Model for Gene Therapy.- Gene Transfer of a Murine Dystophin Minigene Construct.- Gene Therapy in Animal Models of Neurological Disorders.- Neurotrophins and their Receptors.- Regulation of the Human Neurofilament Light and Heavy Genes in Transgenic Mice.