
Ethnicity in Drug Development and Therapeutics
Cambridge University Press
Published on 16. June 2011
Book
Paperback/Softback
152 pages
978-0-521-29252-8 (ISBN)
Description
This book was first published in 2002. It presents an overview of ethnic and racial differences in response to medications and offers insight into the genetic and non-genetic reasons for these differences. The roles of pharmacogenomics and pharmacogenetics in drug development, regulatory aspects of representing minorities in clinical trials, as well as NIH, ICH and FDA guidelines as they pertain to these issues are examined in detail. Finally, various strategies to increase recruitment and retention of minority populations in clinical trials are considered.
More details
Language
English
Place of publication
Cambridge
United Kingdom
Target group
Professional and scholarly
Product notice
Paperback (trade)
Illustrations
Worked examples or Exercises
Dimensions
Height: 234 mm
Width: 156 mm
Thickness: 8 mm
Weight
243 gr
ISBN-13
978-0-521-29252-8 (9780521292528)
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Schweitzer Classification
Other editions
Additional editions
Edyta J. Frackiewicz | Thomas M. Shiovitz | Stanford S. Jhee
Ethnicity in Drug Development and Therapeutics
Book
01/2002
Greenwich Medical Media Ltd
€101.84
Article exhausted; check for reprint
Previous edition
Edyta J. Frackiewicz | Thomas M. Shiovitz | Stanford S. Jhee
Ethnicity in Drug Development and Therapeutics
Book
01/2002
Greenwich Medical Media Ltd
€101.84
Article exhausted; check for reprint
Content
Foreword; Preface; References; 1. Clinical evidence of ethnic and racial differences in drug pharmacodynamics and pharmacokinetics; 2. Ethnic and racial differences in pharmacokinetics of drug metabolism; 3. Ethnic and racial differences in the pharmacokinetics of drugs: absorption, distribution, elimination; 4. Non-genetic basis for ethnic and racial differences in pharmacokinetic parameters; 5. The impact of pharmacokinetics on drug development; 6. Pharmacokinetic analysis of ethnic groups using population methods; 7. Ethnic representation in clinical research and foreign market penetration: regulatory aspects; 8. Recruitment and retention of minority study volunteers.