
Stroke Part I: Basic and epidemiological aspects: Volume 92
Volume 92
Marc Fisher(Editor)
Elsevier (Publisher)
Published on 17. November 2008
Book
Hardback
464 pages
978-0-444-52003-6 (ISBN)
Description
This volume provides a vital and comprehensive resource on stroke, including research, diagnosis, prevention, and treatment modalities. Practitioners in these fields will find invaluable information in this handbook, from basic mechanisms of the disease, to enhanced diagnostic and therapeutic capabilities for patient care.
With the field of cerebrovascular disorders, including stroke, making rapid advancements, clinicians will find illuminating and insightful chapters on the pathophysiological basis of this disorder.
Advances in our understanding of the biochemical background of strokes, coupled with an examination of breakthroughs in epidemiology, genetics, neuroimaging, interventional radiology, surgery, and even clinical psychology are also explored, giving researchers and clinicians a profoundly altered way to approach stroke research, diagnosis, and patient treatment and care.
With the field of cerebrovascular disorders, including stroke, making rapid advancements, clinicians will find illuminating and insightful chapters on the pathophysiological basis of this disorder.
Advances in our understanding of the biochemical background of strokes, coupled with an examination of breakthroughs in epidemiology, genetics, neuroimaging, interventional radiology, surgery, and even clinical psychology are also explored, giving researchers and clinicians a profoundly altered way to approach stroke research, diagnosis, and patient treatment and care.
More details
Series
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Elsevier Science & Technology
Target group
Professional and scholarly
Neurologists
Neuroscience research workers
Product notice
sewn/stitched
Cloth over boards
Illustrations
Approx. 110 illustrations
Dimensions
Height: 268 mm
Width: 202 mm
Thickness: 29 mm
Weight
1492 gr
ISBN-13
978-0-444-52003-6 (9780444520036)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Person
Editor
Professor of Neurology and Radiology, University of Massachusetts Medical School, Worcester, MA, USA
Content
Section 1: Historical perspective:
The history of stroke and cerebrovascular disease.
Section 2: Basic science overview and pathology:
The ischemic cascade and mediators of ischemic injury. Animal models of ischemic stroke. Cerebral blood flow and ischemic penumbra. Neuropathology of ischemic brain injury. Reperfusion injury after stroke: neurovascular proteases and the blood-brain barrier. Gene induction, protein synthesis and related issues. Effects of gender and sex steroids on ischemic injury. Ischemic tolerance as an active and intrinsic neuroprotective mechanism. Vascular endothelium and the blood-brain barrier. A cerebrovascular perspective of atherosclerosis. Blood coagulation and fibrinolysis: mechanisms of thrombosis. Anatomy of the circulation of the brain and spinal cord. Cerebral vascular dysregulation in the ischemic brain. Experimental models in intracerebral hemorrhage.
Section 3: Clinical epidemiology:
The worldwide burden of stroke: current status and future projections. Stroke among women, ethnic groups, young adults and children. Clinical genetic issues in stroke.
Costs and health care system issues. Epidemiological implications of primary and secondary stroke prevention. Stroke recurrence and prognosis after stroke.
The history of stroke and cerebrovascular disease.
Section 2: Basic science overview and pathology:
The ischemic cascade and mediators of ischemic injury. Animal models of ischemic stroke. Cerebral blood flow and ischemic penumbra. Neuropathology of ischemic brain injury. Reperfusion injury after stroke: neurovascular proteases and the blood-brain barrier. Gene induction, protein synthesis and related issues. Effects of gender and sex steroids on ischemic injury. Ischemic tolerance as an active and intrinsic neuroprotective mechanism. Vascular endothelium and the blood-brain barrier. A cerebrovascular perspective of atherosclerosis. Blood coagulation and fibrinolysis: mechanisms of thrombosis. Anatomy of the circulation of the brain and spinal cord. Cerebral vascular dysregulation in the ischemic brain. Experimental models in intracerebral hemorrhage.
Section 3: Clinical epidemiology:
The worldwide burden of stroke: current status and future projections. Stroke among women, ethnic groups, young adults and children. Clinical genetic issues in stroke.
Costs and health care system issues. Epidemiological implications of primary and secondary stroke prevention. Stroke recurrence and prognosis after stroke.