Statistical Aspects Of The Design And Analysis Of Clinical Trials
Published on 12. February 2000
Book
Hardback
352 pages
978-1-86094-153-5 (ISBN)
Description
About 8000 clinical trials are undertaken annually in all areas of medicine, from the treatment of acne to the prevention of cancer. Correct interpretation of the data from such trials depends largely on adequate design and on performing the appropriate statistical analyses. In this book, the statistical aspects of both the design and analysis of trials are described, with particular emphasis on recently developed methods of analysis.
Reviews / Votes
"... given a keen amateur interest and an ability to skip the occasional rather daunting-looking equation this book is surprisingly accessible ... There's an introductory chapter containing an excellent historical overview." Transactions of Royal Society of Tropical Medicine and Hygiene, 2001More details
Language
English
Place of publication
London
United Kingdom
Target group
College/higher education
Professional and scholarly
Dimensions
Height: 240 mm
Width: 161 mm
Thickness: 23 mm
Weight
693 gr
ISBN-13
978-1-86094-153-5 (9781860941535)
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Schweitzer Classification
Persons
Content
An introduction to clinical trials; treatment allocation, the size of trials and reporting results; monitoring trial progress - outcome measures, compliance, dropouts and interim analyses; basic analyses of clinical trials, the generalized linear model and the economic evaluation of trials; simple approaches to the analysis of longitudinal data from clinical trials; models for non-normal longitudinal data from clinical trials; survival analysis; Bayesian methods; meta-analysis.