Etiology and Pathogenesis of Down Syndrome

Partial table of contents:; TRISOMY 21: ORIGIN AND PRENATAL SCREENING.; The Origin of Trisomy in Humans (T. Hassold, et al.).; Antenatal Screening for Down Syndrome (N. Wald).; MOLECULAR STRUCTURE OF CHROMOSOME 21.; The Integrated Map of Human Chromosome 21 (D. Patterson).; MENTAL RETARDATION AND ALZHEIMER DISEASE.; Magnetic Resonance Imaging of the Aging Brain in Down Syndrome (J. Emerson, et al.).; PHENOTYPE OF DOWN SYNDROME.; A Hypothesis to Explain the Immune Defects in Down Syndrome (M. Murphy, et al.).; Considerations of Quantitative Data on Organ Sizes and Cell Numbers and Sizes in Down Syndrome (B. Landing & W. Shankle).; MODELS OF DOWN SYNDROME.; Transgenic Models for Chromosome 21 Gene Dosage Effects (Y. Groner).; EPILOGUE.; Epilogue: Toward the Twenty--First Century with Down Syndrome--A Personal View of How Far We Have Come and of How Far We Can Reasonably Expect to Go (C. Epstein).; Index.