
Epilepsy
A Comprehensive Textbook
Lippincott Williams and Wilkins (Publisher)
2nd Edition
Published on 6. October 2007
Book
Hardback
3056 pages
978-0-7817-5777-5 (ISBN)
Article exhausted; check for reprint
Description
Written and edited by world-renowned authorities, this three-volume work is, to quote a reviewer, "the definitive textbook about seizures and epilepsy". This Second Edition is thoroughly updated and gives you a complete print and multimedia package: the three-volume set plus access to an integrated content Website.
More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; conditions that could be mistaken for epilepsy; and an increasing range of pharmacologic, surgical, and alternative therapies, including vagus nerve stimulation and deep brain stimulation. This edition describes many new antiepileptic drugs, major advances in surgical treatment, and state-of-the-art neuroimaging, EEG, and other technologies for diagnosis and seizure prediction.
A companion Website offers instant access to the complete, fully searchable text, plus an image bank of additional figures, video footage, and annual updates to selected chapters.
More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; conditions that could be mistaken for epilepsy; and an increasing range of pharmacologic, surgical, and alternative therapies, including vagus nerve stimulation and deep brain stimulation. This edition describes many new antiepileptic drugs, major advances in surgical treatment, and state-of-the-art neuroimaging, EEG, and other technologies for diagnosis and seizure prediction.
A companion Website offers instant access to the complete, fully searchable text, plus an image bank of additional figures, video footage, and annual updates to selected chapters.
Reviews / Votes
Journal of the American Medical Association (JAMA), 23-JUL-08, Volume 300, Issue 4, George Lee Morris, III, MD, Regional Epilepsy Center, St. Luke's Medical Center, Milwaukee, WI -- "I recommend the second edition of Epilepsy: A Comprehensive Textbook, edited by Engel and Pedley, for its valuable instruction to practitioners who treat seizures...This text belongs on the shelves of any medical library or physician subspecialist. The chapters are a wonderfully manageable size, often not more than a few pages, and address issues that in other texts receive only a paragraph or two, leaving the reader seeking more information elsewhere. The text is well referenced, citing a variety of original source articles rather than reviews. The different writing styles of the contributors are engaging and allow the reader to enjoy this rather unique experience... "The chapters are easy to peruse and tend to have a narrow focus. I find this a desirable feature when looking for a specific issue. The shorter length means fewer references for any given issue, and it is easier to navigate from text to references and back again. I often question the source of a conclusion, moving back and forth between text and references to discover if I need to review a specific reference. The issues in chapters may vary from the more global, as in "Efficacy of Medications," to the specific, as in "Managing the Single Seizure"-both chapters I enthusiastically recommend. Throughout, the text provides more examples of this variation between a specific and a broad topic, making the book useful to a variety of physicians. "The chapters have wonderful writing styles. They include the grand and sweeping concepts of "Broader Aspects of Treatment," which covers seldom-acknowledged bits of knowledge. This chapter is well worth reading for the newer physician before putting pen to prescription pad. "Routine Monitoring for Safety and Tolerability During Chronic Treatment With Antiepileptic Drugs" is likewise efficient and economical, presenting a condensed, detailed review of appropriate practices and maneuvers. Chapters on candidacy for surgery, hormonal changes with epilepsy treatment, and pharmacogenomics are skillfully written and provide a more focused perspective to the advanced reader. While some chapter authors use the approach of simple titles for each section, others have chosen a question to begin each section as though in a discussion with students in a lecture classroom or clinic hallway. "The text includes a wonderful chapter on the role of the European Regulatory Agencies that provides needed insight into the complicated nature of the drug approval process. The section on the issue of the monotherapy indication bears review for epilepsy physicians and others seeking to understand this issue. Since Europeans have different issues in the approval process, the chapter provides the opportunity to expand a newer physician's understanding of the challenges ahead... "These volumes will, as did their predecessor, become dog-eared and well-worn on my shelf. They will, from time to time, disappear and reappear due to collective use. Libraries will find Epilepsy: A Comprehensive Textbook used frequently, fellows will feel it was a good use of their book funds, and many will patiently wait for the inevitable publication of a valuable third edition."-Journal of the American Medical Association (JAMA)More details
Edition
Second, Plus Integrated Content Website
Language
English
Place of publication
Philadelphia
United States
Target group
Professional and scholarly
Product notice
Cloth over boards
Dimensions
Height: 279 mm
Width: 216 mm
Weight
7220 gr
ISBN-13
978-0-7817-5777-5 (9780781757775)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
New editions

Jerome Engel | Solomon L. Moshe
Epilepsy: A Comprehensive Textbook
Book
11/2023
3rd Edition
WOLTERS KLUWER HEALTH
€653.50
Available immediately
Persons
Editor
Associate editor
Content
VOLUME I
Introduction: What Is Epilepsy?
SECTION 1 EPIDEMIOLOGY, PATHOLOGY, AND GENETICS OF EPILEPSY
Overview: Epidemiology, Pathology, and Genetics
Epilepsy: Historical Perspectives Neuropathology
EPIDEMIOLOGY
Incidence and Prevalence
The Natural History and Prognosis of Epilepsy
NEUROPATHOLOGY
General Neuropathology of Epilepsy
Hippocampal Sclerosis
GENETICS
Genetic Epidemiology
EEG Traits
SECTION II THE NEUROBIOLOGY OF EPILEPSY
Overview: The Neurobiology of Epilepsy
MECHANISMS OF NORMAL NEURONAL EXCITABILITY
Control of Neuronal Excitability
Excitatory Synaptic Transmission
Neocortical Anatomy and Physiology
Thalamocortical Anatomy and Physiology
MECHANISMS OF EPILEPTOGENESIS AND EPILEPTOGENICITY
Genetic Models of Epilepsy
Seizure Mechanisms and Vulnerability in the Developing Brain
SECTION III PHENOMENOLOGY
Overview: Phenomenology
EPILEPTIC SEIZURES
Simple Motor Seizures
Limbic Seizures
Epileptic Spasms
STATUS EPILEPTICUS
Generalized Convulsive Status Epilepticus
Absence Status Epilepticus
Myoclonic Status Epilepticus
EPILEPTIC DISORDERS
Classification of the Epilepsies
SECTION IV DIAGNOSTIC EVALUATION
Overview: Diagnostic Evaluation
ROUTINE INVESTIGATIONS
History and Physical Examination
EEG
Physiologic Basis of the Electroencephalogram and Local Field Potentials
Ictal Electroencephalogram
Polygraphic Recordings
NEUROIMAGING
Positron Emission Tomography
Magnetic Resonance Spectroscopy
Computational Anatomy
NEW DIRECTIONS
Seizure Prediction
Microdialysis
Transcranial Magnetic Stimulation
Cellular Imaging of Epilepsy
NEUROPSYCHOLOGICAL EVALUATION
LONG-TERM MONITORING
VOLUME II
SECTION V GENERAL TREATMENT CONSIDERATIONS
Overview: General Approaches to Treatment
GENERAL CONSIDERATIONS
PRINCIPLES OF DRUG TREATMENT
STRATEGIES FOR PHARMACOTHERAPY
SPECIAL THERAPEUTIC CONSIDERATIONS
ALTERNATIVE APPROACHES
SECTION VI ANTIEPILEPTIC DRUGS
ANTIEPILEPTIC DRUG DEVELOPMENT
ANTIEPILEPTIC DRUGS
SECTION VII SURGICAL THERAPY
CANDIDATE SELECTION
INVASIVE MONITORING TECHNIQUES
FUNCTIONAL MAPPING TECHNIQUES
THERAPEUTIC SURGICAL PROCEDURES
POSTOPERATIVE FOLLOW-UP
SECTION VIII CLINICAL BIOLOGY OF EPILEPSY>/B>
BIORHYTHMS AND THE AUTONOMIC NERVOUS SYSTEM
COMORBIDITY
NEUROENDOCRINOLOGY
VOLUME III
SECTION IX PSYCHIATRIC AND SOCIAL ISSUES
PSYCHIATRIC ISSUES
SOCIAL ISSUES
SECTION X EPILEPSY SYNDROMES
NEONATAL SYNDROMES
SYNDROMES OF INFANCY AND EARLY CHILDHOOD
SYNDROMES OF LATER CHILDHOOD AND ADOLESCENCE
NON AGE-RELATED AND SPECIAL SYNDROMES
DISEASES ASSOCIATED WITH EPILEPSY
SECTION XI DISORDERS THAT CAN BE CONFUSED WITH EPILEPSY
SYSTEMIC DISTURBANCES
NEUROLOGICAL DISTURBANCES
PSYCHIATRIC DISTURBANCES
SECTION XII DELIVERY OF HEALTH CARE AND SOCIOECONOMIC ISSUES
ORGANIZATION OF HEALTH CARE IN DIFFERENT COUNTRIES
SPECIALIZED CENTERS FOR EPILEPSY
COST AND ALLOCATION OF RESOURCES
Subject Index
Introduction: What Is Epilepsy?
SECTION 1 EPIDEMIOLOGY, PATHOLOGY, AND GENETICS OF EPILEPSY
Overview: Epidemiology, Pathology, and Genetics
Epilepsy: Historical Perspectives Neuropathology
EPIDEMIOLOGY
Incidence and Prevalence
The Natural History and Prognosis of Epilepsy
NEUROPATHOLOGY
General Neuropathology of Epilepsy
Hippocampal Sclerosis
GENETICS
Genetic Epidemiology
EEG Traits
SECTION II THE NEUROBIOLOGY OF EPILEPSY
Overview: The Neurobiology of Epilepsy
MECHANISMS OF NORMAL NEURONAL EXCITABILITY
Control of Neuronal Excitability
Excitatory Synaptic Transmission
Neocortical Anatomy and Physiology
Thalamocortical Anatomy and Physiology
MECHANISMS OF EPILEPTOGENESIS AND EPILEPTOGENICITY
Genetic Models of Epilepsy
Seizure Mechanisms and Vulnerability in the Developing Brain
SECTION III PHENOMENOLOGY
Overview: Phenomenology
EPILEPTIC SEIZURES
Simple Motor Seizures
Limbic Seizures
Epileptic Spasms
STATUS EPILEPTICUS
Generalized Convulsive Status Epilepticus
Absence Status Epilepticus
Myoclonic Status Epilepticus
EPILEPTIC DISORDERS
Classification of the Epilepsies
SECTION IV DIAGNOSTIC EVALUATION
Overview: Diagnostic Evaluation
ROUTINE INVESTIGATIONS
History and Physical Examination
EEG
Physiologic Basis of the Electroencephalogram and Local Field Potentials
Ictal Electroencephalogram
Polygraphic Recordings
NEUROIMAGING
Positron Emission Tomography
Magnetic Resonance Spectroscopy
Computational Anatomy
NEW DIRECTIONS
Seizure Prediction
Microdialysis
Transcranial Magnetic Stimulation
Cellular Imaging of Epilepsy
NEUROPSYCHOLOGICAL EVALUATION
LONG-TERM MONITORING
VOLUME II
SECTION V GENERAL TREATMENT CONSIDERATIONS
Overview: General Approaches to Treatment
GENERAL CONSIDERATIONS
PRINCIPLES OF DRUG TREATMENT
STRATEGIES FOR PHARMACOTHERAPY
SPECIAL THERAPEUTIC CONSIDERATIONS
ALTERNATIVE APPROACHES
SECTION VI ANTIEPILEPTIC DRUGS
ANTIEPILEPTIC DRUG DEVELOPMENT
ANTIEPILEPTIC DRUGS
SECTION VII SURGICAL THERAPY
CANDIDATE SELECTION
INVASIVE MONITORING TECHNIQUES
FUNCTIONAL MAPPING TECHNIQUES
THERAPEUTIC SURGICAL PROCEDURES
POSTOPERATIVE FOLLOW-UP
SECTION VIII CLINICAL BIOLOGY OF EPILEPSY>/B>
BIORHYTHMS AND THE AUTONOMIC NERVOUS SYSTEM
COMORBIDITY
NEUROENDOCRINOLOGY
VOLUME III
SECTION IX PSYCHIATRIC AND SOCIAL ISSUES
PSYCHIATRIC ISSUES
SOCIAL ISSUES
SECTION X EPILEPSY SYNDROMES
NEONATAL SYNDROMES
SYNDROMES OF INFANCY AND EARLY CHILDHOOD
SYNDROMES OF LATER CHILDHOOD AND ADOLESCENCE
NON AGE-RELATED AND SPECIAL SYNDROMES
DISEASES ASSOCIATED WITH EPILEPSY
SECTION XI DISORDERS THAT CAN BE CONFUSED WITH EPILEPSY
SYSTEMIC DISTURBANCES
NEUROLOGICAL DISTURBANCES
PSYCHIATRIC DISTURBANCES
SECTION XII DELIVERY OF HEALTH CARE AND SOCIOECONOMIC ISSUES
ORGANIZATION OF HEALTH CARE IN DIFFERENT COUNTRIES
SPECIALIZED CENTERS FOR EPILEPSY
COST AND ALLOCATION OF RESOURCES
Subject Index