
The Pten Family
Cold Spring Harbor Laboratory Press,U.S.
Published on 31. January 2020
Book
Hardback
366 pages
978-1-62182-344-5 (ISBN)
Description
Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers all aspects of PTEN biology and its roles in human diseases. The contributors discuss the structural characteristics of PTEN; its functions at the plasma membrane as well as in the cytoplasm and nucleus; the mutations, interacting partners, and posttranslational modifications that affect its expression levels, subcellular localization, and enzymatic activity; and how this activity ultimately leads to changes in cell growth, migration, and morphology, as well as in gene expression, chromatin dynamics, and the maintenance of genomic stability. A historical perspective that covers the initial discovery and subsequent characterization of PTEN is also included.
More details
Series
Language
English
Place of publication
New York
United States
Product notice
sewn/stitched
Cloth over boards
With dust jacket
Dimensions
Height: 260 mm
Width: 180 mm
Thickness: 26 mm
Weight
885 gr
ISBN-13
978-1-62182-344-5 (9781621823445)
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Schweitzer Classification
Persons
Editor
Genomic Medicine Institute Lerner Research Institute
National Cancer Centre Singapore
Princess Margaret Cancer Centre Uhn