Pharmacology of Ionic Channel Function: Activators and Inhibitors
Published on 24. September 2012
Book
Paperback/Softback
XXXI, 662 pages
978-3-642-63030-9 (ISBN)
Description
Cells maintain uneven distribution of Na, K and Ca ions across the cell membrane and membranes of intracellular organellae. Cells exert their functions by allowing for some ion to cross the membrane through ion channels which either produces an electrical effect across the membrane or switches on a series of chemical or physicochemical reactions. This is a comprehensive book about these vitally important ion channels with detailed description of the molecular structure and function and especially of activators and inhibitors. All chapters are written by renowned specialists in their field.
More details
Series
Edition
Softcover reprint of the original 1st ed. 2000
Language
English
Place of publication
Berlin
Germany
Publishing group
Springer Berlin
Target group
Professional and scholarly
Research
Illustrations
105 s/w Abbildungen, 2 farbige Abbildungen
XXXI, 662 p. 107 illus., 2 illus. in color.
Dimensions
Height: 235 mm
Width: 155 mm
Thickness: 38 mm
Weight
1042 gr
ISBN-13
978-3-642-63030-9 (9783642630309)
DOI
10.1007/978-3-642-57083-4
Schweitzer Classification
Other editions
Additional editions
M. Endo | Y. Kurachi | M. Mishina
Pharmacology of Ionic Channel Function: Activators and Inhibitors
Activators and Inhibitors
Book
07/2000
Springer
€534.99
Shipment within 10-15 days
Content
Section I: Voltage-Dependent Ion Channels.- A. Voltage-Dependent Na Channels.- 1 Structure and Functions of Voltage-Dependent Na+ Channels.- 2 Sodium Channel Blockers and Activators.- B. Voltage-Dependent Ca-Channels.- 3 Classification and Function of Voltage-Gated Calcium Channels.- Structure of the Voltage-Dependent L-Type Calcium Channel.- 5 Ca2+ Channel Antagonists and Agonists.- C. Voltage-Dependent K-Channels.- 6 Overview of Potassium Channel Families: Molecular Bases of the Functional Diversity.- 7 Pharmacology of Voltage-Gated Potassium Channels.- 8 Voltage-Gated Calcium-Modulated Potassium Channels of Large Unitary Conductance: Structure, Diversity, and Pharmacology.- 9 Classical Inward Rectifying Potassium Channels: Mechanisms of Inward Rectification.- 10 ATP-Dependent Potassium Channels in the Kidney.- 11 Structure and Function of ATP-Sensitive K+ Channels.- 12 G Protein-Gated K+ Channels.- 13 Potassium Channels with Two Pore Domains.- 14 Cardiac K+ Channels and Inherited Long QT Syndrome.- Section II: Ligand Operated Ion Channels.- 15 Gating of Ion Channels by Transmitters: The Range of Structures of the Transmitter-Gated Channels.- 16 Molecular Diversity, Structure, and Function of Glutamate Receptor Channels.- 17 Glutamate Receptor Ion Channels: Activators and Inhibitors.- 18 Structure, Diversity, Pharmacology, and Pathology of Glycine Receptor Chloride Channels.- 19 GABAA Receptor Chloride Ion Channels.- 20 P2X Receptors for ATP: Classification, Distribution, and Function.- 21 The 5-HT3 Receptor Channel: Function, Activation and Regulation.- 22 Cyclic Nucleotide-Gated Channels: Classification, Structure and Function, Activators and Inhibitors.- Section III: Miscellaneous Ion Channels - Intracellular Ca Release Channels.- 23 Regulation of Ryanodine Receptor Calcium Release Channels.- 24 Regulation of IP3 Receptor Ca2+ Release Channels.- 25 Ca2+-Activated Non-Selective Cation Channels.