
The Kidney: Volume 7
Volume 7
Academic Press
Will be published approx. on 1. November 2026
Book
Hardback
300 pages
978-0-443-44885-0 (ISBN)
Description
The Kidney, Volume Seven in the Stem Cell Innovation in Health and Disease series, explores the emerging potential of stem cell therapies in treating kidney diseases. With their natural regenerative and anti-inflammatory properties, stem cells offer a promising approach to restoring essential kidney functions and mitigating damage. This volume highlights how stem cell therapies may modulate immune responses, promote tissue repair, and replace damaged kidney cells, offering hope for chronic and acute renal conditions. Key developments include the injection of mesenchymal stem cells (MSCs) into damaged kidneys where they can differentiate into kidney cell types and aid in healing.
In addition, urine-derived stem cells have also shown significant potential in improving kidney function in preclinical studies. Additionally, innovative techniques like incorporating MSCs into compact dialysis machines are explored, enabling delivery of pro-repair factors directly to the kidneys during blood filtration. While there are currently no FDA-approved stem cell treatments for kidney diseases, ongoing clinical trials aim to evaluate their safety and efficacy. This volume compiles cutting-edge research, discussing various cell sources, underlying mechanisms, observed therapeutic outcomes, and the practical challenges of clinical translation. By presenting a clear picture of current advances and future directions, this book serves as a vital resource for scientists, clinicians, and health innovators seeking to harness stem cell technology in nephrology.
In addition, urine-derived stem cells have also shown significant potential in improving kidney function in preclinical studies. Additionally, innovative techniques like incorporating MSCs into compact dialysis machines are explored, enabling delivery of pro-repair factors directly to the kidneys during blood filtration. While there are currently no FDA-approved stem cell treatments for kidney diseases, ongoing clinical trials aim to evaluate their safety and efficacy. This volume compiles cutting-edge research, discussing various cell sources, underlying mechanisms, observed therapeutic outcomes, and the practical challenges of clinical translation. By presenting a clear picture of current advances and future directions, this book serves as a vital resource for scientists, clinicians, and health innovators seeking to harness stem cell technology in nephrology.
More details
Series
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
Professional and scholarly
Product notice
sewn/stitched
Cloth over boards
Dimensions
Height: 276 mm
Width: 216 mm
Weight
449 gr
ISBN-13
978-0-443-44885-0 (9780443448850)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Persons
Dr. Ahmed Hashash is currently Endowed Chair and Distinguished Professor at Elizabeth City State University, campus of the University of North Carolina (UNC). He received his PhD from Manchester University, UK. Dr. Hashash was a fellow of the California Institute of Regenerative Medicine (CIRM) and New York University Medical School (MSSM), USA. He was Assistant Professor and Principal Investigator of Stem Cell & Regenerative Medicine at School of Medicine University of California, USA. Dr Hashash was Associate Professor of Biomedicine at the University of Edinburgh (UK) Zhejiang Intl. campus and Texas A &M University, USA from 2017 to 2025. He has published more than 40 papers in reputed international journals, 10 books with Elsevier and Springer and over 20 book chapters, and is serving as an editorial board member of repute. Dr Elhefnawy studied doctor degree in nephrology at Claude Bernard University (Lyon-France). He was the president of Gharbia medical syndicate, Egypt for several years. He served as House officer and Resident of Internal Medicine at Tanta University Hospital, Egypt. He is consultant of Nephrology at Menshawi Hospital of Tanta University, Egypt.
Editor
Endowed Chair, Distinguished Professor, University of North Carolina, USA
Physician Consultant, Internal Medicine, Tanta University Hospital, Egypt
Content
1. Stem cell-based kidney organoid culture system as innovative model of kidney development and diseases
2. Innovative therapeutic gene editing technologies (e.g. CRISPR/Cas9 systems) in stem cell engineering, kidney disorders and diseases
3. Role of genetically modified animal models in kidney diseases and disorders
4. Advances in stem cell-based therapy of kidney diseases and disorders
5. The potential of amniotic fluid derived stem cells (AFSCs) in kidney diseases and disorders
6. Applications of mesenchymal stem cell related therapies for kidney diseases and disorders
7. The use of mesenchymal stem cell-derived exosomes in kidney disorders and diseases
8. The gold standard iPSC-derived cells and technology in modeling kidney diseases and disorders
9. Roles of bone marrow-derived stem cells (BMDSCs) in kidney injury, repair and diseases
10. General Discussion, Conclusion Remark and Future Direction
2. Innovative therapeutic gene editing technologies (e.g. CRISPR/Cas9 systems) in stem cell engineering, kidney disorders and diseases
3. Role of genetically modified animal models in kidney diseases and disorders
4. Advances in stem cell-based therapy of kidney diseases and disorders
5. The potential of amniotic fluid derived stem cells (AFSCs) in kidney diseases and disorders
6. Applications of mesenchymal stem cell related therapies for kidney diseases and disorders
7. The use of mesenchymal stem cell-derived exosomes in kidney disorders and diseases
8. The gold standard iPSC-derived cells and technology in modeling kidney diseases and disorders
9. Roles of bone marrow-derived stem cells (BMDSCs) in kidney injury, repair and diseases
10. General Discussion, Conclusion Remark and Future Direction