
Protein Bioinformatics
An Algorithmic Approach to Sequence and Structure Analysis
Wiley (Publisher)
1st Edition
Published on 19. December 2003
Book
Hardback
380 pages
978-0-470-84839-5 (ISBN)
Description
Genomics and bioinformatics play an increasingly important and transformative role in medicine, society and agriculture. The mapping of the human genome has revealed 35,000 or so genes which might code for more than one protein, resulting in 100,000 proteins for the humans alone. Since proteins are attractive targets for developing drugs, efforts are now underway to map sequences and assign functions to many novel proteins. This book takes the novel approach to cover both the sequence and structure analysis of proteins in one volume and from an algorithmic perspective.
Key features of the book include:
* Provides a comprehensive introduction to the analysis of protein sequence and structure analysis.
* Takes an algorithmic approach, relying on computational methods rather than theoretical.
* Provides an integrated presentation of theory, examples, exercises and applications.
* Includes coverage of both protein structure, and sequence, analysis.
* Accessible enough for biologists, yet rigorous enough for computer scientists and mathematicians.
* Supported by a Web site featuring exercises, solutions, images, and computer programs.
Visit this website for exercises with solutions, computer programs, errata and additional material:
http://www.ii.uib.no/proteinbioinformatics/
More details
Product info
GB
Edition
1., Auflage
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Product notice
sewn/stitched
Cloth over boards
Dimensions
Height: 240 mm
Width: 161 mm
Thickness: 25 mm
Weight
736 gr
ISBN-13
978-0-470-84839-5 (9780470848395)
Schweitzer Classification
Persons
Ingvar Eidhammer is a professor in the Department of Informatics at the University of Bergen,Norway. He is also associated with the Centre for Cancer Biomarkers established at the University of Bergen.
Inge Jonassen is a professor in the Department of Informatics at the University of Bergen, Norway. His field of research is bioinformatics, the development and application of informatics methods for the analysis of molecular biology data.
William R. Taylor is the author of Protein Bioinformatics: An Algorithmic Approach to Sequence and Structure Analysis, published by Wiley.
Inge Jonassen is a professor in the Department of Informatics at the University of Bergen, Norway. His field of research is bioinformatics, the development and application of informatics methods for the analysis of molecular biology data.
William R. Taylor is the author of Protein Bioinformatics: An Algorithmic Approach to Sequence and Structure Analysis, published by Wiley.
Content
Preface.
Acknowledgements.
Part I: SEQUENCE ANALYSIS.
1. Pairwise Global Alignment of Sequences.
2 Pairwise Local Alignment and Database Search.
3. Statistical Analysis.
4.Multiple Global Alignment and Phylogenetic Trees.
5. Scoring Matrices.
6. Profiles.
7. Sequence Patterns.
Part II: STRUCTURE ANALYSIS
8. Structures and Structure Descriptions.
9. Superposition and Dynamic Programming.
10. Geometric Techniques.
11. Clustering: Combining Local Similarities.
12. Significance and Assessment of Structure Comparisons.
13. Multiple Structure Comparison.
14. Protein Structure Classification.
Part III: SEQUENCE-STRUCTUREANALYSIS.
15. Structure Prediction: Threading.
Appendix A: Basics in Mathematics, Probability and Algorithms.
Appendix B: Introduction to Molecular Biology.
References.
Index.