Calreticulin
2nd Edition
Published on 31. July 2003
Book
Hardback
XX, 282 pages
978-0-306-47845-1 (ISBN)
Description
The book focuses on the latest discoveries on calreticulin, calnexin and other endoplasmic reticulum proteins. Calreticulin has been implicated to affect diverse cellular function and play a role in many pathologies including protein folding disorders, cardiac pathologies, cancer and autoimmunity. This book contains contributions from the world leaders in the area of endoplasmic reticulum function, protein folding, Calcium homeostasis and autoimmunity. It raises many intriguing questions about calreticulin, calnexin and the endoplasmic reticulum and gives a unique opportunity to realize the significance of these calcium-binding chaperones. The book is unique in every respect and we are not aware of any other publication focusing on these aspects of endoplasmic reticulum biology. Because of a central role of endoplasmic reticulum, calreticulin and calnexin in virtually all cellular functions, the book should be of interest to everyone in the biological sciences.
More details
Series
Edition
Second Edition 2003
Language
English
Place of publication
New York
United States
Publishing group
Springer Science+Business Media
Target group
Professional and scholarly
Research
Edition type
New edition
Illustrations
XX, 282 p.
Dimensions
Height: 241 mm
Width: 160 mm
Thickness: 24 mm
Weight
686 gr
ISBN-13
978-0-306-47845-1 (9780306478451)
DOI
10.1007/978-1-4419-9258-1
Schweitzer Classification
Other editions
Additional editions
Paul Eggleton | Marek Michalak
Calreticulin
E-Book
12/2012
2nd Edition
Springer
€149.79
Available for download
Paul Eggleton | Marek Michalak
Calreticulin
Book
11/2012
2nd Edition
Springer
€160.49
Shipment within 7-9 days
Content
0.- Preface.- Abbreviations.- 1. Introduction to Calreticulin.- 2. Biochemical and Molecular Properties of Calreticulin.- 3. A Chaperone System for Glycoprotein Folding: The Calnexin/Calreticulin Cycle.- 4. Calnexin, an ER Integral Membrane Chaperone in Health and Disease.- 5. Sub-Cellular Distribution of Calreticulin.- 6. Calnexin and Calreticulin, Molecular Chaperones of the Endoplasmic Reticulum.- 7. Roles of Calreticulin and Calnexin in Myeloperoxidase Synthesis.- 9. The Role of Calnexin and Calreticulin in MHC Class I Assembly.- 10. Calreticulin and the Endoplasmic Reticulum in Plant Cell Biology.- 11. Modulation of Calcium Homeostasis by the Endoplasmic Reticulum in Health and Disease.- 12. Calnexin and Calreticulin, ER Associated Modulators of Calcium Transport in the ER.- 13. ER Calcium and ER Chaperones: New Players in Apoptosis?.- 14. Calreticulin in Cytotoxic Lymphocyte-Mediated Cytotoxicity.- 15. A Role for Calreticulin in the Clearance of Apoptotic Cells and in the Innate Immune System.- 17. Calreticulin's Role(s) in Autoimmune Disorders.- 18. Cell Surface Calreticulin: Role in Signaling Thrombospondin Anti-Adhesive Activity.- 19. Calreticulin Regulation of Lung Endothelial NOS Activity.- 20. Role of Calreticulin in Leishmania Parasite Secretory Pathway and Pathogenesis.- 21. The Hookworm Calreticulin Conundrum.- 22. Calreticulin in C. elegans.- 23. Calreticulin Deficient Mouse.- 267.- Appendix II: Amino Acid Sequence of Calreticulin.