Brain Opioid Systems in Reproduction
Published in August 1989
Book
Hardback
379 pages
978-0-19-857694-5 (ISBN)
Description
Many aspects of reproduction are controlled by the brain. For example, ovulation, birth and lactation are dependent upon signals from the brain directed at the endocrine system. The brain is also responsible for ensuring that the animal behaves in a way appropriate for these changing reproductive states. The nerve cells responsible for controlling the endocrine system and sexual behaviour receive much information about the internal and external environment. The details of how this information is integrated within the brain is in general poorly understood. However, in recent years nerve cells producing peptides with opioid-like activity have been found to play a significant, integrative role in this control process. This work represents an examination of the new knowledge in the control of reproduction in both male and female. Subjects covered include the role of brain opioid in the control of gonadotrophin secretion and the onset of puberty, the regulation of seasonal breeding and sexual behaviour, as well as the release of oxytocin and thus involvement in parturition and lactation.
More details
Language
English
Place of publication
Oxford
United Kingdom
Target group
College/higher education
Professional and scholarly
Illustrations
91 line drawings, 2 half-tones, 7 colour plates, bibliography, index
Dimensions
Height: 234 mm
Width: 156 mm
Weight
812 gr
ISBN-13
978-0-19-857694-5 (9780198576945)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Content
Part 1 Opioids, gonadal steroids and gonadotrophin secretion: ovarian steroids and endogenous opioid peptide action in control of the rat LH surge, R.H.Lustig et al; endocrine regulation of brain opioid receptors, P.Limonta et al; oestradiol/progesterone regulation of hypothalamic neuropeptide mRNA levels - correlation with LH and prolactin secretion, J.D.White et al; opioid peptides and seasonal reproduction, G.A.Lincoln et al; do brain opioid peptides regulate the onset of puberty?, M.Wilkinson et al. Part 2 Opioids and afferents to GnRH neurones: opioids in the steroid-adrenergic circuit regulating LH secretion - dynamics and diversities, S.P.Kalra et al; opioid inhibition of brain stem projections to the medial preoptic area in female rats, R.Grossman and R.G.Dyer; relationship of endogenous opioid peptide axons to GnRH neurones in the rat, G.E.Hoffman et al; B-endorphin in hypophysial portal blood, I.J.Clarke et al; opioid-mediated inhibition of sexual behaviour and luteinizing hormone secretion by corticotrophin-releasing hormone, O.F.X.Almeida et al. Part 3 Opioids, endocrine function and sexual behaviour: specific roles for B-endorphin in reproduction and sexual behaviour, J. Herbert; a psychopharmacological characterization of the opioid suppression of sexual behaviour in the female rat, J.B.Wiesner and R.L.Moss; opioid peptide inhibition of sexual behaviour in female rats, P.Sodersten et al; brain opioids and sexual behaviour in the male rat, M.Baum. Part 4 Opioid peptides and oxytocin: opioids, oxytocin and parturition, G.Leng and J.A.Russell; relaxin, opioids and the timing of birth in rats, A.J.Summerlee; cross-inhibition of oxytocin neurones during activation of the vasopressin system, J.Y.Summy-Long; secretory terminals of oxytocin neurones as a site of opioid modulation, R.J.Bicknell and B.-G.Zhao. Part 5 Opioid peptides and reproduction in the human: opioid peptides, oxytocin and human reproduction, J.Seckl and S.L.Lightman; opioid peptides, prolactin and gonadotrophin regulation in the human, A.Grossman. Part 6 Perspectives: mechanisms of opioid modulation in other systems - relevance to neuroendocrinology, A. Herz and O.F.X.Almeida.