Host Modulation Therapy in Periodontics

Chronic inflammatory periodontal disease is caused by host immune responses to periodontal microorganisms. Over the past decade researchers has produced remarkable advances in our understanding of host immune responses. With the increase in the understanding of host response to inflammation newer avenues have emerged for the treatment of periodontal disease. The emerging awareness of inflammation and its control in periodontal disease management enlightened the importance of exploring inflammatory pathways and mediators, thus setting the newer opportunities for the development of new prevention and treatment strategies of a widespread disease.