
Biological Reaction Engineering
Dynamic Modelling Fundamentals with Simulation Examples
Wiley-VCH (Publisher)
2nd Edition
Published on 18. July 2003
Book
Hardback
XVI, 508 pages
978-3-527-30759-3 (ISBN)
Article exhausted; check for reprint
Description
In this book, the modelling of dynamic biological engineering processes is presented in a highly understandable way using the unique combination of simplified fundamental theory and direct hands-on computer simulation. The mathematics is kept to a minimum, and yet the 60 examples supplied on a CD-ROM illustrate almost every aspect of biological engineering science. Each example is described in detail, including the model equations. The programms are written in the modern user-friendly simulation language Berkeley Madonna, which can be run on both Windows PC and Power-Macintosh computers.
Madonna solves models comprising many ordinary differential equations using very simple programming, including arrays. It is so powerful that the model parameters may be defined as "sliders", which allow the effect of their change on the model behavior to be seen almost immediately. Data may be included for curve fitting, and sensitivity or multiple runs may be performed. The results can be seen simultaneously on multiple-graph windows or by using overlays. The examples can be varied to fit any real situation, and the suggested exercises provide practical guidance.
The extensive experience of the authors, both in university teaching and international courses, is reflected in this well-balanced presentation, which is suitable for the teacher, the student, the biochemist or the engineer.
Reviews / Votes
".ist das Buch eine echte Bereicherung und führt hoffentlich bei den Lesern zum angestrebten Schub an Interesse und Fähigkeit. Ich werde es jedenfalls in Griffweite neben dem Laptop postieren und den Studierenden in den einschlägigen Vorlesungen empfehlen."C. Posten, KarlsruheCIT 3/04"Besonders hervorzuheben ist der für ein Lehrbuch sehr erfreuliche durchgehend praktische Bezug. Das Buch ist meines Erachtens besonders gut für angehende Fachhochschulingenieure sowie für Studenten in Nebenfächern geeignet. Darüber hinaus kann es als erste Lektüre für denjenigen dienen, der sich grob in das Fachgebiet einarbeiten möchte."Chemie Ingenieur Technik, B. Nienhaus, FrankfurtMore details
Edition
2., vollst. überarb. u. erw. Auflage
Language
English
Place of publication
Weinheim
Germany
Target group
Professional and scholarly
Biotechnologen, Bioingenieure, Chemiker in der Industrie, Ingenieure für Chemie
Edition type
Revised edition
Illustrations
309
297 s/w Abbildungen, 12 s/w Tabellen
Illustrations
Dimensions
Height: 24 cm
Width: 17 cm
Weight
1166 gr
ISBN-13
978-3-527-30759-3 (9783527307593)
Schweitzer Classification
Other editions
New editions

Elmar Heinzle | Irving J. Dunn | John Ingham
Biological Reaction Engineering
Dynamic Modeling Fundamentals with 80 Interactive Simulation Examples
Book
04/2021
3rd Edition
Wiley-VCH
€175.00
Shipment within 5-7 days
Previous edition
Irving J. Dunn | Elmar Heinzle | John Ingham
Biological Reaction Engineering
Principles, Applications and Modelling with PC Simulation
Book
11/1992
Wiley-VCH
€136.18
Article exhausted; check for reprint
Content
PART I PRINCIPLES OF BIOREACTOR MODELLING
MODELLING PRINCIPLES
Fundamentals of Modelling
Development and Meaning of Dynamic Differential Balances
Formulation of Balance Equations
BASIC BIOREACTOR DESIGN
Information Inputs
Bioreactor Operations
BIOLOGICAL KINETICS
Enzyme Kinetics
Simple Microbial Kinetics
Structured Kinetic Models
BIOREACTOR MODELLING
General Balances for Tank-type Biological Reactors
Modelling Tubular Plug Flow Bioreactors
MASS TRANSFER
Mass Transfer in Biological Reactors
Interphase Gas-Liquid Mass Transfer
General Oxygen Balances for Gas-Liquid Transfer
Models for Oxygen in Large Scale Bioreactors
DIFFUSION AND BIOLOGICAL REACTION IN IMMOBILIZED BIOCATALYST SYSTEMS
External Mass Transfer
Internal Diffusion and Reaction within Biocatalysts
AUTOMATIC BIOPROCESS CONTROL FUNDAMENTALS
Elements of Feedback Control
Types of Controller Action
Controller Tuning
Advanced Control Strategies
Concepts for Bioprocess Control
REFERENCES
PART II DYNAMIC BIOPROCESS SIMULATION EXAMPLES AND THE BERKELEY MADONNA SIMULATION LANGUAGE
SIMULATION EXAMPLES OF BIOLOGICAL REACTION PROCESSES USING BERKELEY MADONNA
Introductory Examples
Batch Reactors
Fed Batch Reactors
Continuous Reactors
Oxygen Uptake Systems
Controlled Reactors
Diffusion Systems
Multi-Organism and Structured Models
Animal Cell Reactor Examples
APPENDIX: USING THE BERKELEY MADONNA LANGUAGE