Principles of Protein X-ray Crystallography

X-ray crystallography has been a vital method for studying the structure of proteins and other macromolecules for many years. As the importance of proteins continues to grow in a wide range of research fields form basic biochemistry and biophysics to pharmaceutical development and biotechnology, more and more researchers have found a knowledge of X-ray diffraction to be an indispensable tool. This book provides the theoretical background necessary to understand how the structures of proteins are determined at atomic resolution. It is intended to be an introduction for graduate students, postdoctoral researchers, and established scientists who want to apply protein crystallography in their own endeavours, or need to understand the subject in order to critically evaluate the literature.