Bioinformatics and Computational Biology
Description
This book constitutes the refereed proceedings of the 21st Brazilian Congress on BioInformatics, X-Meeting 2025, held in João Pessoa, Brazil, during June 3-6, 2025.
The 14 full papers and 2 short papers included in this book were carefully reviewed and selected from 35 submissions. These papers present ongoing research on Bioinformatics, as well as their application in a number of diverse areas such as DNA and Genomics, RNA and transcriptomic, Proteins and Proteomics, Database and Software Development, Phylogeny and Evolution, Systems Biology and Modeling, among others by considering applications on health, agriculture and microorganism and plants.
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Content
.- Detective Challenge: a card-game approach to teach bioinformatics and gene expression in high schools.
.- Dissecting Structural Differences in Tumoral and Control Co-expression Networks through Centrality Measures.
.- Diversity of GH18 Family of Chitinases in Arthropods.
.- Transcriptomic Profiling and Regulatory Network Reconstruction Uncovers Central Genes in HTLV Infection Progression.
.- Predicting microsatellite instability from whole slide images using texture features.
.- The Extended N-Terminal Domain of VPAC1 Isoform 2 Acts as a Self-Inhibitory Element: Insights from Molecular Dynamics Simulations.
.- Using Machine Learning and Graph-based Signatures to Evaluate Normal and Decreased Function CYP2D6 Haplotypes.
.- Immune Remodeling and Dysbiosis May Distinguish the Microenvironments of Gastric Adenocarcinoma and Peritumoral Tissue.
.- Viral Sequence Database Manager Version 2 (VSDBMv2): A Distributed Framework for Viral Genomic Analysis and Epitope Mapping.
.- In silico assessment of immune cross protection between BCoV and SARS-CoV-2.
.- Exploring the Therapeutic Potential of Flavonoids Present in Propolis Against Colorectal Cancer Through a Network Pharmacology Approach.
.- BITSER: an alignment-free approach for feature extraction and classification of viral genomes.
.-Towards Fast Binding Affinity Scoring in Protein-Protein Complexes via Interatomic Contacts and Linear Regression.
.- Characterization of the Terpene Synthase Gene Family and Its Role in Response to Water Deprivation in Stylosanthes scabra.
.- Protein Dimension DB: A Unified Protein Repository for Representation Learning and Functional Analysis.
.- Forecasting using SARIMAX model and LSTM approach for arboviruses using exogenous climatic variables in predicting dengue incidence.