
Virus as Populations
Composition, Complexity, Quasispecies, Dynamics, and Biological Implications
Esteban Domingo(Author)
Academic Press
2nd Edition
Published on 1. November 2019
Book
Paperback/Softback
426 pages
978-0-12-816331-3 (ISBN)
Description
Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included.
The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere.
The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere.
More details
Edition
2nd edition
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
Professional and scholarly
grad students, researchers, med students and investigators in virology, microbiology, and infectious disease; pharmacologists and vaccinologists; theoretical biologists; evolutionary biologists.
Dimensions
Height: 235 mm
Width: 191 mm
Weight
790 gr
ISBN-13
978-0-12-816331-3 (9780128163313)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

Esteban Domingo
Virus as Populations
Composition, Complexity, Quasispecies, Dynamics, and Biological Implications
E-Book
11/2019
2nd Edition
Academic Press
€104.00
Available for download
Previous edition

Book
10/2015
Academic Press
€92.50
Shipment within 15-20 days
Person
Esteban Domingo studied chemistry and biochemistry at the University of Barcelona, Spain and spent postdoctoral stays at the University of California, Irvine and the University of Zuerich. His main interests are the quasispecies structure of RNA viruses and the development of new antiviral strategies. He is presently Professor of Research of the Spanish Research Council (CSIC) at Centro de Biologia Molecular "Servero Ochoa" in Madrid.
Content
1. Introduction to Virus Origins and Their Role in Biological Evolution2. Molecular Basis of Genetic Variation of Viruses 3. Darwinian Principles Acting on Highly Mutable Viruses4. Dynamics of Virus Populations and Their Hosts5. Viral Fitness as a Measure of Adaptation 6. Virus Population Dynamics Examined with Experimental Model Systems 7. Long-term Virus Evolution in Nature8. Quasispecies Dynamics in Disease Prevention and Control9. Trends in Antiviral Strategies10. Collective Population Effects in Non-Viral Systems