Pharmacotherapy: A Pathophysiologic Approach
7th Edition
Published on 16. July 2008
Book
Hardback
2592 pages
978-0-07-147899-1 (ISBN)
Description
The seventh edition of the benchmark evidence-based pharmacotherapy text--now in full color!
Includes Online Learning Center--that features 11 additional chapters, learning objectives, interactive questions, and more!
A Doody's Core Title ESSENTIAL PURCHASE!
4 STAR DOODY'S REVIEW!
"This book is, by far, one of the best in pharmacy. It is an exceptionally useful reference for both pharmacists and pharmacy students. It communicates a wealth of information that is well researched and referenced. The seventh edition is a much needed update."--Doody's Review ServiceWhen it comes to helping you develop a mastery of evidence-based medicine for optimal patient outcomes, no book can match Pharmacotherapy: A Pathophysiologic Approach. Like the discipline it covers, the scope of this trusted resource goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. Pharmacotherapy delivers everything you need to know to provide safe, effective drug therapy across the full range of therapeutic categories.
The book also delves into psychosocial issues that affect compliance--topics related to a patient's ability to understand and manage often-complex therapy--and lifestyle changes that may reduce the need for drug therapy or improve pharmacotherapeutic outcomes.
FEATURES
Key Concepts in each chapter
Critical Presentation boxes that summarize common disease signs and symptoms Clinical Controversies boxes that examine complicated issues you face when providing drug therapy Therapeutic recommendations in each disease-specific chapter Evaluation of Therapeutic Outcomes Information in each disease-specific chapter containing key monitoring guidelines NEW MATERIAL! including chapters on Pulmonary Hypertension, Disorders of Calcium and Phosphorous Homeostatis, and Multiple Myeloma NEW! Expanded evidence-based recommendations NEW! Extended coverage of the timely issue of palliative care and pain medicine
Includes Online Learning Center--that features 11 additional chapters, learning objectives, interactive questions, and more!
A Doody's Core Title ESSENTIAL PURCHASE!
4 STAR DOODY'S REVIEW!
"This book is, by far, one of the best in pharmacy. It is an exceptionally useful reference for both pharmacists and pharmacy students. It communicates a wealth of information that is well researched and referenced. The seventh edition is a much needed update."--Doody's Review ServiceWhen it comes to helping you develop a mastery of evidence-based medicine for optimal patient outcomes, no book can match Pharmacotherapy: A Pathophysiologic Approach. Like the discipline it covers, the scope of this trusted resource goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. Pharmacotherapy delivers everything you need to know to provide safe, effective drug therapy across the full range of therapeutic categories.
The book also delves into psychosocial issues that affect compliance--topics related to a patient's ability to understand and manage often-complex therapy--and lifestyle changes that may reduce the need for drug therapy or improve pharmacotherapeutic outcomes.
FEATURES
Key Concepts in each chapter
Critical Presentation boxes that summarize common disease signs and symptoms Clinical Controversies boxes that examine complicated issues you face when providing drug therapy Therapeutic recommendations in each disease-specific chapter Evaluation of Therapeutic Outcomes Information in each disease-specific chapter containing key monitoring guidelines NEW MATERIAL! including chapters on Pulmonary Hypertension, Disorders of Calcium and Phosphorous Homeostatis, and Multiple Myeloma NEW! Expanded evidence-based recommendations NEW! Extended coverage of the timely issue of palliative care and pain medicine
More details
Edition
7th edition
Language
English
Place of publication
New York
United States
Publishing group
McGraw-Hill Education - Europe
Target group
Professional and scholarly
Illustrations
530 Illustrations
Dimensions
Height: 284 mm
Width: 221 mm
Thickness: 83 mm
Weight
5335 gr
ISBN-13
978-0-07-147899-1 (9780071478991)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Persons
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
L. Michael Posey, RPh, is president of Pharmacy Editorial & News Services (PENS) in Athens, Georgia, and an editor for the APhA periodicals Journal of the American Pharmacists Association, Pharmacy Today, and APhA DrugInfoLine. He also assists with drug information content for APhAs cutting-edge Web site, www.pharmacist.com. During a career spanning two decades as a pharmacy communicator, Posey has served as editor of The Consultant Pharmacist and the American Journal of Hospital Pharmacy, and is an editor of the textbook Pharmacotherapy: A Pathophysiologic Approach.
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
L. Michael Posey, RPh, is president of Pharmacy Editorial & News Services (PENS) in Athens, Georgia, and an editor for the APhA periodicals Journal of the American Pharmacists Association, Pharmacy Today, and APhA DrugInfoLine. He also assists with drug information content for APhAs cutting-edge Web site, www.pharmacist.com. During a career spanning two decades as a pharmacy communicator, Posey has served as editor of The Consultant Pharmacist and the American Journal of Hospital Pharmacy, and is an editor of the textbook Pharmacotherapy: A Pathophysiologic Approach.
Content
PHARMACOTHERAPY 7/E - Table of Contents
Section 1: Foundation IssuesSection Editor: L. Michael Posey
1.Pharmacoeconomics: Principles, Methods, and Applications (Web-only)Lisa A. Sanchez
2.Health Outcomes and Quality of Life (Web-only)Stephen Joel Coons
3.Evidence-Based Medicine (Web-only)Elaine Chiquette and L. Michael Posey
4.Documentation of Pharmacy Services (Web-only)George E. MacKinnon, III and Neil J. MacKinnon
5.Clinical Pharmacokinetics and PharmacodynamicsLarry A. Bauer
6.PharmacogeneticsLarisa H. Cavallari and Y. W. Francis Lam
7.PediatricsMilap C. Nahata and Carol Taketomo
8.GeriatricsCatherine I. Starner, Shelly L. Gray, David R. P. Guay, Emily R. Hajjar, Steven M. Handler, and Joseph T. Hanlon
9.PharmacoepidemiologyAndy Stergachis, Thomas K. Hazlet, and Denise Boudreau
10.Clinical ToxicologyPeter A. Chyka
11.Emergency Preparedness: Identification and Management of Biological Exposures (Web-only)Colleen M. Terriff, Jason E. Brouillard, Lisa T. Costanigro, and Jessica S. Gruber
12.Emergency Preparedness: Identification and Management of Chemical and Radiological Exposures (Web-only)Greene Shepherd and Richard B. Schwartz
Section 2: Cardiovascular DisordersSection Editor: Robert L. Talbert
13.Cardiovascular TestingRobert Chilton and Robert L. Talbert
14.Cardiopulmonary ResuscitationJeffrey F. Barletta and Jeffrey L. Wilt
15.HypertensionJoseph J. Saseen and Eric J. MacLaughlin
16.Heart FailureRobert B. Parker, Jo E. Rodgers, and Larisa H. Cavallari
17.Ischemic Heart DiseaseRobert L. Talbert
18.Acute Coronary SyndromesSarah A. Spinler and Simon de Denus
19.The ArrhythmiasCynthia A. Sanoski, Marieke Dekker Schoen, and Jerry L. Bauman
20.Diastolic Heart Failure and the Cardiomyopathies
21.Venous ThromboembolismStuart T. Haines, Daniel M. Witt, and Edith A. Nutescu
22.StrokeSusan C. Fagan, David C. Hess
23.HyperlipidemiaRobert L. Talbert
24.Peripheral Arterial DiseaseBarbara J. Hoeben and Robert L. Talbert
25.Use of Vasopressors and Inotropes in the Pharmacotherapy of ShockRobert MacLaren, Maria I. Rudis, and Joseph F. Dasta
26.Hypovolemic ShockBrian L. Erstad
Section 3: Respiratory DisordersSection Editor: Robert L. Talbert
27.Introduction to Pulmonary Function TestingJay I. Peters and Stephanie M. Levine
28.AsthmaH. William Kelly and Christine A. Sorkness
29.Chronic Obstructive Pulmonary DiseaseDennis M. Williams and Sharya V. Bourdet
30.Pulmonary HypertensionRobert Talbert, Rebecca Boudreaux, Rebecca Owens
31.Drug-Induced Pulmonary DiseasesHengameh H. Raissy, Michelle Harkins, and Patricia L. Marshik
32.Cystic FibrosisGary Milavetz
Section 4: Gastrointestinal DisordersSection Editor: Joseph T. DiPiro
33.Evaluation of the Gastrointestinal TractKeith M. Olsen, Marie A. Chisholm, and Mark W. Jackson
34.Gastroesophageal Reflux DiseaseDianne B. Williams and Robert R. Schade
35.Peptic Ulcer DiseaseRosemary R. Berardi and Lynda S. Welage
36.Inflammatory Bowel DiseaseBrian A. Hemstreet and Joseph T. DiPiro
37.Nausea and VomitingCecily V. DiPiro
38.Diarrhea, Constipation, and Irritable Bowel SyndromeWilliam J. Spruill and William E. Wade
39.Portal Hypertension and CirrhosisJulie Sease Altman, Edward G. Timm, and James J. Stragand
40.Drug-Induced Liver DiseaseWilliam R. Kirchain and Rondall E. Allen
41.PancreatitisRosemary R. Berardi and Patricia A. Montgomery
42.Viral HepatitisPaulina Deming, Renee-Claude Mercier, and Manjunath P. Pai
43.Drug Therapy Individualization in Patients with Hepatic Disease or Genetic Alterations in Drug Metabolizing ActivityY. W. Francis Lam
Section 5: Renal DisordersSection Editor: Gary R. Matzke
44Quantification of Renal FunctionThomas C. Dowling
45Acute Renal FailureWilliam Dager and Anne Spencer
46Chronic Kidney Disease: Progression-Modifying TherapiesMelanie S. Joy, Abhijit Kshirsagar, and Nora Franceschini
47Chronic Kidney Disease: Management of ComplicationsJoanna Q. Hudson
48Hemodialysis and Peritoneal Dialysis (Web-only)Edward F. Foote and Harold J. Manley
49Drug-Induced Kidney DiseaseThomas D. Nolin and Jonathan Himmelfarb
50GlomerulonephritisAlan H. Lau
51Drug Therapy Individualization for Patients with Renal InsufficiencyGary R. Matzke and Reginald F. Frye
52Disorders of Sodium and Water HomeostasisJames D. Coyle, Melanie S. Joy, and Gerald A. Hladik
53Disorders of Calcium and Phosphorus Homeostasis Amy Barton Pai and Mark Rohrschieb
54Disorders of Potassium and Magnesium HomeostasisDonald F. Brophy and Todd W. B. Gehr
55Acid-Base DisordersGary R. Matzke, John W. Devlin, and Paul M. Palevsky
Section 6: Neurologic DisordersSection Editor: Barbara G. Wells
56Evaluation of Neurologic IllnessSusan C. Fagan and Fenwick T. Nichols
57Multiple SclerosisJacquelyn L. Bainbridge and John R. Corboy
58EpilepsySusan J. Rogers and Jose E. Cavazos
59Status EpilepticusStephanie J. Phelps, Collin A. Hovinga, and James W. Wheless
60Acute Management of the Brain Injury PatientBradley A. Boucher and Shelly D. Timmons
61Parkinson's DiseaseJack J. Chen, Merlin V. Nelson, and David M. Swope
62Pain Management and Palliative CareTerry J. Baumann and Jennifer Strickland
63Headache DisordersDeborah S. Minor and Marion R. Wofford
Section 7: Psychiatric DisordersSection Editor: Barbara G. Wells
64Evaluation of Psychiatric IllnessPatricia A. Marken, Mark E. Schneiderhan, and Stuart Munro
65Childhood DisordersJulie Ann Dopheide, Jane Tran Tesoro, and Michael Malkin
66Eating DisordersSteven C. Stoner
67Alzheimer's DiseasePatricia W. Slattum, Russell H. Swerdlow, and Angela Massey Hill
68Substance-Related Disorders: Overview and Depressants, Stimulants, and HallucinogensPaul L. Doering and Lisa A. Boothby
69Substance-Related Disorders: Alcohol, Nicotine, and CaffeinePaul L. Doering, W. Klugh Kennedy, and Lisa A. Boothby
70SchizophreniaM. Lynn Crismon, Tami R. Argo, and Peter F. Buckley
71Depressive DisordersChristian J. Teter, Judith C. Kando, Barbara G. Wells, and Peggy E. Hayes
72Bipolar DisorderShannon J. Drayton and Benjamin Weinstein
73Anxiety Disorders I: Generalized Anxiety, Panic, and Social Anxiety DisordersCynthia K. Kirkwood, Sarah T. Melton
74Anxiety Disorders II: Posttraumatic Stress Disorder and Obsessive-Compulsive DisorderCynthia K. Kirkwood, Eugene H. Makela, and Barbara G. Wells
75Sleep DisordersJohn M. Dopp and Bradley G. Phillips77Diabetes MellitusCurtis L. Triplitt, Charles A. Reasner, and William L. Isley
78Thyroid DisordersSteven I. Sherman and Robert L. Talbert
79Adrenal Gland DisordersJohn G. Gums and Shawn Anderson
80Pituitary Gland DisordersAmy Heck Sheehan, Jack A. Yanovski, and Karim Anton Calis
Section 9: Gynecologic and Obstetric DisordersSection Editor: Barbara G. Wells
81Pregnancy and Lactation: Therapeutic ConsiderationsDenise L. Walbrandt Pigarelli, Connie K. Kraus, and Beth E. Potter
82ContraceptionLori M. Dickerson, Sarah P. Shrader, and Vanessa A. Diaz
83Menstruation-Related DisordersElena M. Umland, Lara C. Weinstein, Edward Buchanan
84EndometriosisDeborah A. Sturpe
85Hormone Therapy in WomenSophia N. Kalantaridou, Susan R. Davis, and Karim Anton Calis
Section 10: Urologic DisordersSection Editor: L. Michael Posey
86Erectile DysfunctionMary Lee
87Management of Benign Prostatic HyperplasiaMary Lee
88Urinary IncontinenceEric S. Rovner, Jean Wyman, Thomas Lackner, and David Guay
Section 11: Immunologic DisordersSection Editor: Gary C. Yee
89Function and Evaluation of the Immune SystemPhilip D. Hall, Nicole A. Weimert
90Systemic Lupus Erythematosus and Other Collagen-Vascular DiseasesJeffrey C. Delafuente and Kimberly A. Cappuzzo
91Allergic and Pseudoallergic Drug ReactionsJoseph T. DiPiro
92Solid-Organ TransplantationKristine S. Schonder and Heather J. Johnson
Section 12: Rheumatologic DisordersSection Editor: L. Michael Posey
93Osteoporosis and Other Metabolic Bone DiseasesMary Beth O'Connell and Sheryl F. Vondracek
94Rheumatoid ArthritisArthur A. Schuna
95OsteoarthritisLucinda M. Buys and Mary Elizabeth Elliott
96Gout and HyperuricemiaMichael E. Ernst, Elizabeth C. Clark, David W. Hawkins
Section 13: Ophthalmic and Otolaryngological DisordersSection Editor: L. Michael Posey
97.GlaucomaRichard G. Fiscella, Timothy S. Lesar, and Deepak P. Edward
98.Allergic RhinitisJ. Russell May and Philip H. Smith
Section 14: Dermatologic DisordersSection Editor: L. Michael Posey
99.Dermatologic Drug Reactions and Self-Treatable Skin DisordersNina H. Cheigh
100.Acne VulgarisDennis P. West, Amy Loyd, Kimberly A. Bauer, Lee E. West, Laura Scuderi, and Giuseppe Micali
101.PsoriasisDennis P. West, Amy Loyd, Lee E. West, Kimberly A. Bauer, Maria Letizia Musumeci, and Giuseppe Micali
102.Atopic DermatitisNina H. Cheigh
Section 15: Hematologic DisordersSection Editor: Gary C. Yee
103.HematopoiesisWilliam P. Petros and Michael Craig
104.AnemiasBeata Ineck, Barbara J. Mason, and William Lyons
105.Coagulation DisordersBetsy Bickert and Char Witmer
106.Sickle Cell AnemiaC.Y. Jennifer Chan and Reginald Moore
107.Drug-Induced Hematologic DisordersDale H. Whitby and Thomas E. Johns
Section 16: Infectious DiseasesSection Editor: Joseph T. DiPiro
108.Laboratory Tests to Direct Antimicrobial PharmacotherapyMichael J. Rybak and Jeffrey R. Aeschlimann
109.Antimicrobial Regimen SelectionDavid S. Burgess
110.Central Nervous System InfectionsIsaac F. Mitropoulos, Elizabeth D. Hermsen, Jeremy A. Schafer, and John C. Rotschafer
111.Lower Respiratory Tract InfectionsMark L. Glover and Michael D. Reed
112.Upper Respiratory Tract InfectionsYasmin Khaliq, Sarah Forgie, and George Zhanel
113.InfluenzaElizabeth D. Hermsen and Mark E. Rupp
114.Skin and Soft Tissue InfectionsDouglas N. Fish, Susan L. Pe
ndland, and Larry H. Danziger
115.Infective EndocarditisMichael A. Crouch and Angie Veverka
116.TuberculosisCharles A. Peloquin
117.Gastrointestinal Infections and Enterotoxigenic PoisoningsSteven Martin and Rose Jung
118.Intraabdominal InfectionsJoseph T. DiPiro and Thomas R. Howdieshell
119.Parasitic DiseasesJ. V. Anandan
120.Urinary Tract Infections and ProstatitisElizabeth A. Coyle and Randall A. Prince
121.Sexually Transmitted DiseasesLeroy C. Knodel
122.Bone and Joint InfectionsEdward P. Armstrong and Allan D. Friedman
123.Sepsis and Septic ShockS. Lena Kang-Birken and Joseph T. DiPiro
124.Superficial Fungal InfectionsThomas E. R. Brown and Thomas W. F. Chin
125.Invasive Fungal InfectionsPeggy L. Carver
126.Infections in Immunocompromised PatientsDouglas N. Fish
127.Antimicrobial Prophylaxis in SurgerySalmaan Kanji and John W. Devlin
128.Vaccines, Toxoids, and Other ImmunobiologicsMary S. Hayney
129.Human Immunodeficiency Virus InfectionPeter L. Anderson, Thomas N. Kakuda, and Courtney
V. Fletcher
Section 17: Oncologic DisordersSection Editor: Gary C. Yee
130.Cancer Treatment and ChemotherapyPatrick J. Medina and Chris Fausel
131.Breast CancerLaura Boehnke Michaud, Janet L. Espirito, and Francisco J. Esteva
132.Lung CancerJeannine S. McCune and Deborah A. Frieze
133.Colorectal CancerPatrick J. Medina, Weijing Sun, and Lisa E. Davis
134.Prostate CancerJill M. Kolesar
135.LymphomasVal R. Adams and Gary C. Yee
136.Ovarian CancerJudith A. Smith and Judith K. Wolf
137.Acute LeukemiasHelen L. Leather and Betsy Bickert Poon
138.Chronic LeukemiasAmy M. Pick, Marcel Devetten, Timothy R. McGuire
139.Multiple MyelomaTimothy R. McGuire
140.Myelodysplastic Syndromes (Web-only)Julianna A. Burzynski and Trevor McKibbin
141.Skin CancerRowena N. Schwartz and Lindsay J. Corporon
142.Hematopoietic Stem Cell TransplantationJanelle B. Perkins and Gary C. Yee
Section 18: Nutritional DisordersSection Editor: Gary R. Matzke
143.Assessment of Nutrition Status and Nutrition RequirementsKatherine Hammond Chessman and Vanessa J. Kumpf
144.Prevalence and Significance of MalnutritionGordon Sacks and Catherine M. Crill
145.Parenteral NutritionTodd W. Mattox and Pamela D. Reiter
146.Enteral NutritionVanessa J. Kumpf and Katherine Hammond Chessman
147.Nutritional Considerations in Major Organ FailureBrian M. Hodges and Mark DeLegge
148.ObesityJohn V. St. Peter and Charles J. Billington
Section 1: Foundation IssuesSection Editor: L. Michael Posey
1.Pharmacoeconomics: Principles, Methods, and Applications (Web-only)Lisa A. Sanchez
2.Health Outcomes and Quality of Life (Web-only)Stephen Joel Coons
3.Evidence-Based Medicine (Web-only)Elaine Chiquette and L. Michael Posey
4.Documentation of Pharmacy Services (Web-only)George E. MacKinnon, III and Neil J. MacKinnon
5.Clinical Pharmacokinetics and PharmacodynamicsLarry A. Bauer
6.PharmacogeneticsLarisa H. Cavallari and Y. W. Francis Lam
7.PediatricsMilap C. Nahata and Carol Taketomo
8.GeriatricsCatherine I. Starner, Shelly L. Gray, David R. P. Guay, Emily R. Hajjar, Steven M. Handler, and Joseph T. Hanlon
9.PharmacoepidemiologyAndy Stergachis, Thomas K. Hazlet, and Denise Boudreau
10.Clinical ToxicologyPeter A. Chyka
11.Emergency Preparedness: Identification and Management of Biological Exposures (Web-only)Colleen M. Terriff, Jason E. Brouillard, Lisa T. Costanigro, and Jessica S. Gruber
12.Emergency Preparedness: Identification and Management of Chemical and Radiological Exposures (Web-only)Greene Shepherd and Richard B. Schwartz
Section 2: Cardiovascular DisordersSection Editor: Robert L. Talbert
13.Cardiovascular TestingRobert Chilton and Robert L. Talbert
14.Cardiopulmonary ResuscitationJeffrey F. Barletta and Jeffrey L. Wilt
15.HypertensionJoseph J. Saseen and Eric J. MacLaughlin
16.Heart FailureRobert B. Parker, Jo E. Rodgers, and Larisa H. Cavallari
17.Ischemic Heart DiseaseRobert L. Talbert
18.Acute Coronary SyndromesSarah A. Spinler and Simon de Denus
19.The ArrhythmiasCynthia A. Sanoski, Marieke Dekker Schoen, and Jerry L. Bauman
20.Diastolic Heart Failure and the Cardiomyopathies
21.Venous ThromboembolismStuart T. Haines, Daniel M. Witt, and Edith A. Nutescu
22.StrokeSusan C. Fagan, David C. Hess
23.HyperlipidemiaRobert L. Talbert
24.Peripheral Arterial DiseaseBarbara J. Hoeben and Robert L. Talbert
25.Use of Vasopressors and Inotropes in the Pharmacotherapy of ShockRobert MacLaren, Maria I. Rudis, and Joseph F. Dasta
26.Hypovolemic ShockBrian L. Erstad
Section 3: Respiratory DisordersSection Editor: Robert L. Talbert
27.Introduction to Pulmonary Function TestingJay I. Peters and Stephanie M. Levine
28.AsthmaH. William Kelly and Christine A. Sorkness
29.Chronic Obstructive Pulmonary DiseaseDennis M. Williams and Sharya V. Bourdet
30.Pulmonary HypertensionRobert Talbert, Rebecca Boudreaux, Rebecca Owens
31.Drug-Induced Pulmonary DiseasesHengameh H. Raissy, Michelle Harkins, and Patricia L. Marshik
32.Cystic FibrosisGary Milavetz
Section 4: Gastrointestinal DisordersSection Editor: Joseph T. DiPiro
33.Evaluation of the Gastrointestinal TractKeith M. Olsen, Marie A. Chisholm, and Mark W. Jackson
34.Gastroesophageal Reflux DiseaseDianne B. Williams and Robert R. Schade
35.Peptic Ulcer DiseaseRosemary R. Berardi and Lynda S. Welage
36.Inflammatory Bowel DiseaseBrian A. Hemstreet and Joseph T. DiPiro
37.Nausea and VomitingCecily V. DiPiro
38.Diarrhea, Constipation, and Irritable Bowel SyndromeWilliam J. Spruill and William E. Wade
39.Portal Hypertension and CirrhosisJulie Sease Altman, Edward G. Timm, and James J. Stragand
40.Drug-Induced Liver DiseaseWilliam R. Kirchain and Rondall E. Allen
41.PancreatitisRosemary R. Berardi and Patricia A. Montgomery
42.Viral HepatitisPaulina Deming, Renee-Claude Mercier, and Manjunath P. Pai
43.Drug Therapy Individualization in Patients with Hepatic Disease or Genetic Alterations in Drug Metabolizing ActivityY. W. Francis Lam
Section 5: Renal DisordersSection Editor: Gary R. Matzke
44Quantification of Renal FunctionThomas C. Dowling
45Acute Renal FailureWilliam Dager and Anne Spencer
46Chronic Kidney Disease: Progression-Modifying TherapiesMelanie S. Joy, Abhijit Kshirsagar, and Nora Franceschini
47Chronic Kidney Disease: Management of ComplicationsJoanna Q. Hudson
48Hemodialysis and Peritoneal Dialysis (Web-only)Edward F. Foote and Harold J. Manley
49Drug-Induced Kidney DiseaseThomas D. Nolin and Jonathan Himmelfarb
50GlomerulonephritisAlan H. Lau
51Drug Therapy Individualization for Patients with Renal InsufficiencyGary R. Matzke and Reginald F. Frye
52Disorders of Sodium and Water HomeostasisJames D. Coyle, Melanie S. Joy, and Gerald A. Hladik
53Disorders of Calcium and Phosphorus Homeostasis Amy Barton Pai and Mark Rohrschieb
54Disorders of Potassium and Magnesium HomeostasisDonald F. Brophy and Todd W. B. Gehr
55Acid-Base DisordersGary R. Matzke, John W. Devlin, and Paul M. Palevsky
Section 6: Neurologic DisordersSection Editor: Barbara G. Wells
56Evaluation of Neurologic IllnessSusan C. Fagan and Fenwick T. Nichols
57Multiple SclerosisJacquelyn L. Bainbridge and John R. Corboy
58EpilepsySusan J. Rogers and Jose E. Cavazos
59Status EpilepticusStephanie J. Phelps, Collin A. Hovinga, and James W. Wheless
60Acute Management of the Brain Injury PatientBradley A. Boucher and Shelly D. Timmons
61Parkinson's DiseaseJack J. Chen, Merlin V. Nelson, and David M. Swope
62Pain Management and Palliative CareTerry J. Baumann and Jennifer Strickland
63Headache DisordersDeborah S. Minor and Marion R. Wofford
Section 7: Psychiatric DisordersSection Editor: Barbara G. Wells
64Evaluation of Psychiatric IllnessPatricia A. Marken, Mark E. Schneiderhan, and Stuart Munro
65Childhood DisordersJulie Ann Dopheide, Jane Tran Tesoro, and Michael Malkin
66Eating DisordersSteven C. Stoner
67Alzheimer's DiseasePatricia W. Slattum, Russell H. Swerdlow, and Angela Massey Hill
68Substance-Related Disorders: Overview and Depressants, Stimulants, and HallucinogensPaul L. Doering and Lisa A. Boothby
69Substance-Related Disorders: Alcohol, Nicotine, and CaffeinePaul L. Doering, W. Klugh Kennedy, and Lisa A. Boothby
70SchizophreniaM. Lynn Crismon, Tami R. Argo, and Peter F. Buckley
71Depressive DisordersChristian J. Teter, Judith C. Kando, Barbara G. Wells, and Peggy E. Hayes
72Bipolar DisorderShannon J. Drayton and Benjamin Weinstein
73Anxiety Disorders I: Generalized Anxiety, Panic, and Social Anxiety DisordersCynthia K. Kirkwood, Sarah T. Melton
74Anxiety Disorders II: Posttraumatic Stress Disorder and Obsessive-Compulsive DisorderCynthia K. Kirkwood, Eugene H. Makela, and Barbara G. Wells
75Sleep DisordersJohn M. Dopp and Bradley G. Phillips77Diabetes MellitusCurtis L. Triplitt, Charles A. Reasner, and William L. Isley
78Thyroid DisordersSteven I. Sherman and Robert L. Talbert
79Adrenal Gland DisordersJohn G. Gums and Shawn Anderson
80Pituitary Gland DisordersAmy Heck Sheehan, Jack A. Yanovski, and Karim Anton Calis
Section 9: Gynecologic and Obstetric DisordersSection Editor: Barbara G. Wells
81Pregnancy and Lactation: Therapeutic ConsiderationsDenise L. Walbrandt Pigarelli, Connie K. Kraus, and Beth E. Potter
82ContraceptionLori M. Dickerson, Sarah P. Shrader, and Vanessa A. Diaz
83Menstruation-Related DisordersElena M. Umland, Lara C. Weinstein, Edward Buchanan
84EndometriosisDeborah A. Sturpe
85Hormone Therapy in WomenSophia N. Kalantaridou, Susan R. Davis, and Karim Anton Calis
Section 10: Urologic DisordersSection Editor: L. Michael Posey
86Erectile DysfunctionMary Lee
87Management of Benign Prostatic HyperplasiaMary Lee
88Urinary IncontinenceEric S. Rovner, Jean Wyman, Thomas Lackner, and David Guay
Section 11: Immunologic DisordersSection Editor: Gary C. Yee
89Function and Evaluation of the Immune SystemPhilip D. Hall, Nicole A. Weimert
90Systemic Lupus Erythematosus and Other Collagen-Vascular DiseasesJeffrey C. Delafuente and Kimberly A. Cappuzzo
91Allergic and Pseudoallergic Drug ReactionsJoseph T. DiPiro
92Solid-Organ TransplantationKristine S. Schonder and Heather J. Johnson
Section 12: Rheumatologic DisordersSection Editor: L. Michael Posey
93Osteoporosis and Other Metabolic Bone DiseasesMary Beth O'Connell and Sheryl F. Vondracek
94Rheumatoid ArthritisArthur A. Schuna
95OsteoarthritisLucinda M. Buys and Mary Elizabeth Elliott
96Gout and HyperuricemiaMichael E. Ernst, Elizabeth C. Clark, David W. Hawkins
Section 13: Ophthalmic and Otolaryngological DisordersSection Editor: L. Michael Posey
97.GlaucomaRichard G. Fiscella, Timothy S. Lesar, and Deepak P. Edward
98.Allergic RhinitisJ. Russell May and Philip H. Smith
Section 14: Dermatologic DisordersSection Editor: L. Michael Posey
99.Dermatologic Drug Reactions and Self-Treatable Skin DisordersNina H. Cheigh
100.Acne VulgarisDennis P. West, Amy Loyd, Kimberly A. Bauer, Lee E. West, Laura Scuderi, and Giuseppe Micali
101.PsoriasisDennis P. West, Amy Loyd, Lee E. West, Kimberly A. Bauer, Maria Letizia Musumeci, and Giuseppe Micali
102.Atopic DermatitisNina H. Cheigh
Section 15: Hematologic DisordersSection Editor: Gary C. Yee
103.HematopoiesisWilliam P. Petros and Michael Craig
104.AnemiasBeata Ineck, Barbara J. Mason, and William Lyons
105.Coagulation DisordersBetsy Bickert and Char Witmer
106.Sickle Cell AnemiaC.Y. Jennifer Chan and Reginald Moore
107.Drug-Induced Hematologic DisordersDale H. Whitby and Thomas E. Johns
Section 16: Infectious DiseasesSection Editor: Joseph T. DiPiro
108.Laboratory Tests to Direct Antimicrobial PharmacotherapyMichael J. Rybak and Jeffrey R. Aeschlimann
109.Antimicrobial Regimen SelectionDavid S. Burgess
110.Central Nervous System InfectionsIsaac F. Mitropoulos, Elizabeth D. Hermsen, Jeremy A. Schafer, and John C. Rotschafer
111.Lower Respiratory Tract InfectionsMark L. Glover and Michael D. Reed
112.Upper Respiratory Tract InfectionsYasmin Khaliq, Sarah Forgie, and George Zhanel
113.InfluenzaElizabeth D. Hermsen and Mark E. Rupp
114.Skin and Soft Tissue InfectionsDouglas N. Fish, Susan L. Pe
ndland, and Larry H. Danziger
115.Infective EndocarditisMichael A. Crouch and Angie Veverka
116.TuberculosisCharles A. Peloquin
117.Gastrointestinal Infections and Enterotoxigenic PoisoningsSteven Martin and Rose Jung
118.Intraabdominal InfectionsJoseph T. DiPiro and Thomas R. Howdieshell
119.Parasitic DiseasesJ. V. Anandan
120.Urinary Tract Infections and ProstatitisElizabeth A. Coyle and Randall A. Prince
121.Sexually Transmitted DiseasesLeroy C. Knodel
122.Bone and Joint InfectionsEdward P. Armstrong and Allan D. Friedman
123.Sepsis and Septic ShockS. Lena Kang-Birken and Joseph T. DiPiro
124.Superficial Fungal InfectionsThomas E. R. Brown and Thomas W. F. Chin
125.Invasive Fungal InfectionsPeggy L. Carver
126.Infections in Immunocompromised PatientsDouglas N. Fish
127.Antimicrobial Prophylaxis in SurgerySalmaan Kanji and John W. Devlin
128.Vaccines, Toxoids, and Other ImmunobiologicsMary S. Hayney
129.Human Immunodeficiency Virus InfectionPeter L. Anderson, Thomas N. Kakuda, and Courtney
V. Fletcher
Section 17: Oncologic DisordersSection Editor: Gary C. Yee
130.Cancer Treatment and ChemotherapyPatrick J. Medina and Chris Fausel
131.Breast CancerLaura Boehnke Michaud, Janet L. Espirito, and Francisco J. Esteva
132.Lung CancerJeannine S. McCune and Deborah A. Frieze
133.Colorectal CancerPatrick J. Medina, Weijing Sun, and Lisa E. Davis
134.Prostate CancerJill M. Kolesar
135.LymphomasVal R. Adams and Gary C. Yee
136.Ovarian CancerJudith A. Smith and Judith K. Wolf
137.Acute LeukemiasHelen L. Leather and Betsy Bickert Poon
138.Chronic LeukemiasAmy M. Pick, Marcel Devetten, Timothy R. McGuire
139.Multiple MyelomaTimothy R. McGuire
140.Myelodysplastic Syndromes (Web-only)Julianna A. Burzynski and Trevor McKibbin
141.Skin CancerRowena N. Schwartz and Lindsay J. Corporon
142.Hematopoietic Stem Cell TransplantationJanelle B. Perkins and Gary C. Yee
Section 18: Nutritional DisordersSection Editor: Gary R. Matzke
143.Assessment of Nutrition Status and Nutrition RequirementsKatherine Hammond Chessman and Vanessa J. Kumpf
144.Prevalence and Significance of MalnutritionGordon Sacks and Catherine M. Crill
145.Parenteral NutritionTodd W. Mattox and Pamela D. Reiter
146.Enteral NutritionVanessa J. Kumpf and Katherine Hammond Chessman
147.Nutritional Considerations in Major Organ FailureBrian M. Hodges and Mark DeLegge
148.ObesityJohn V. St. Peter and Charles J. Billington