Pharmacotherapy: A Pathophysiologic Approach, Tenth Edition
10th Edition
Published on 16. January 2017
Book
Hardback
2512 pages
978-1-259-58748-1 (ISBN)
Description
The landmark text on how to achieve optimal patient outcomes through evidence-based medication therapy
Pharmacotherapy: A Pathophysiologic Approach is written to help readers advance the quality of patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. The scope of this trusted classic goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. Readers will find everything they need to provide safe, effective drug therapy across the full range of therapeutic categories.
This edition is enriched by more than 300 expert contributors, and every chapter has been revised and updated to reflect the latest in evidence-based information and recommendations. Important features such as Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy make this text an essential learning tool for students, patient-focused pharmacists, and other health care providers.
? A section on personalized pharmacotherapy appears in most sections
? All diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches are in full color to clearly distinguish treatment pathways
? New drug monitoring tables have been added
? Most of the disease-oriented chapters have incorporated evidence-based treatment guidelines that when available, include ratings of the level of evidence to support the key therapeutic approaches
? Twenty-four online-only chapters are available at www.pharmacotherapyonline.com
Pharmacotherapy: A Pathophysiologic Approach is written to help readers advance the quality of patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. The scope of this trusted classic goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. Readers will find everything they need to provide safe, effective drug therapy across the full range of therapeutic categories.
This edition is enriched by more than 300 expert contributors, and every chapter has been revised and updated to reflect the latest in evidence-based information and recommendations. Important features such as Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy make this text an essential learning tool for students, patient-focused pharmacists, and other health care providers.
? A section on personalized pharmacotherapy appears in most sections
? All diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches are in full color to clearly distinguish treatment pathways
? New drug monitoring tables have been added
? Most of the disease-oriented chapters have incorporated evidence-based treatment guidelines that when available, include ratings of the level of evidence to support the key therapeutic approaches
? Twenty-four online-only chapters are available at www.pharmacotherapyonline.com
More details
Persons
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
L. Michael Posey, RPh, is president of Pharmacy Editorial & News Services (PENS) in Athens, Georgia, and an editor for the APhA periodicals Journal of the American Pharmacists Association, Pharmacy Today, and APhA DrugInfoLine. He also assists with drug information content for APhAs cutting-edge Web site, www.pharmacist.com. During a career spanning two decades as a pharmacy communicator, Posey has served as editor of The Consultant Pharmacist and the American Journal of Hospital Pharmacy, and is an editor of the textbook Pharmacotherapy: A Pathophysiologic Approach.
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide
L. Michael Posey, RPh, is president of Pharmacy Editorial & News Services (PENS) in Athens, Georgia, and an editor for the APhA periodicals Journal of the American Pharmacists Association, Pharmacy Today, and APhA DrugInfoLine. He also assists with drug information content for APhAs cutting-edge Web site, www.pharmacist.com. During a career spanning two decades as a pharmacy communicator, Posey has served as editor of The Consultant Pharmacist and the American Journal of Hospital Pharmacy, and is an editor of the textbook Pharmacotherapy: A Pathophysiologic Approach.
Content
Contributors
Foreword
Foreword to the First Edition
Preface
Section 1 Foundation Issues
e1. Health Literacy and Medication Use
e2. Cultural Competency
e3. Medication Safety Principles and Practices
e4. Clinical Pharmacokinetics and Pharmacodynamics
e5. Pharmacogenetics
e6. Pediatrics
e7. Geriatrics
e8. Palliative Care
e9. Clinical Toxicology
e10. Clinical Management of Potential Bioterrorism-related Conditions
Section 2 Cardiovascular Disorders
e11. Cardiovascular Testing
12. Cardiac Arrest
13. Hypertension
14. Chronic Heart Failure
15. Acute Decompensated Heart Failure
16. Stable Ischemic Heart Disease
17. Acute Coronary Syndromes
18. The Arrhythmias
19. Venous Thromboembolism
20. Stroke
21. Dyslipidemia
e22. Peripheral Arterial Disease
23. Use of Vasopressors and Inotropes in the Pharmacotherapy of Shock
24. Hypovolemic Shock
e25. Introduction to Pulmonary Function Testing
Section 3 Respiratory Disorders
26. Asthma
27. Chronic Obstructive Pulmonary Disease
28. Pulmonary Arterial Hypertension
29. Cystic Fibrosis
e30. Drug-Induced Pulmonary Diseases
Section 4 Gastrointestinal Disorders
e31. Evaluation of the Gastrointestinal Tract
32. Gastroesophageal Reflux Disease
33. Peptic Ulcer Disease and Related Disorders
34. Inflammatory Bowel Disease
35. Nausea and Vomiting
36. Diarrhea, Constipation, and Irritable Bowel Syndrome
37. Portal Hypertension and Cirrhosis
e38. Drug-Induced Liver Disease
39. Pancreatitis
40. Viral Hepatitis
41. Celiac Disease
Section 5 Renal Disorders
e42. Evaluation of Kidney Function
43. Acute Kidney Injury
44. Chronic Kidney Disease
45. Hemodialysis and Peritoneal Dialysis
46. Drug-Induced Kidney Disease
47. Glomerulonephritis
48. Drug Therapy Individualization for Patients with Chronic Kidney Disease
49. Disorders of Sodium and Water Homeostasis
50. Disorders of Calcium and Phosphorus Homeostasis
51. Disorders of Potassium and Magnesium Homeostasis
52. Acid-Base Disorders
Section 6 Neurologic Disorders
e53. Evaluation of Neurologic Illness
54. Alzheimer Disease
55. Multiple Sclerosis
56. Epilepsy
57. Status Epilepticus
58. Acute Management of the Brain Injury Patient
59. Parkinson Disease
60. Pain Management
61. Headache Disorders
Section 7 Psychiatric Disorders
e62. Assessment of Psychiatric Disorders
63. Attention Deficit/Hyperactivity Disorder
64. Eating Disorders
65. Substance-Related Disorders I: Overview and Depressants, Stimulants, and Hallucinogens
66. Substance-Related Disorders II: Alcohol, Nicotine, and Caffeine
67. Schizophrenia
68. Major Depressive Disorder
69. Bipolar Disorder
70. Anxiety Disorders: Generalized Anxiety, Panic, and Social Anxiety Disorders
71. Posttraumatic Stress Disorder and Obsessive-Compulsive Disorder
72. Sleep-Wake Disorders
73. Disorders Associated with Intellectual Disabilities
Section 8 Endocrinologic Disorders
74. Diabetes Mellitus
75. Thyroid Disorders
76. Adrenal Gland Disorders
e77. Pituitary Gland Disorders
Section 9 Gynecologic and Obstetric Disorders
78. Pregnancy and Lactation: Therapeutic Considerations
79. Contraception
80. Menstruation-Related Disorders
81. Endometriosis
82. Hormone Therapy in Women
Section 10 Urologic Disorders
83. Erectile Dysfunction
84. Benign Prostatic Hyperplasia
85. Urinary Incontinence
Section 11 Immunologic Disorders
e86. Function and Evaluation of the Immune System
87. Systemic Lupus Erythematosus
e88. Drug Allergy
89. Solid-Organ Transplantation
Section 12 Rheumatologic Disorders
90. Osteoarthritis
91. Rheumatoid Arthritis
92. Osteoporosis and Osteomalacia
93. Gout and Hyperuricemia
Section 13 Ophthalmic and Otolaryngological Disorders
94. Glaucoma
95. Allergic Rhinitis
Section 14 Dermatologic Disorders
96. Acne Vulgaris
97. Psoriasis
98. Atopic Dermatitis
e99. Dermatologic Drug Reactions and Common Skin Conditions
Section 15 Hematologic Disorders
100. Anemias
101. Coagulation Disorders
102. Sickle Cell Disease
e103. Drug-Induced Hematologic Disorders
Section 16 Infectious Diseases
e104. Laboratory Tests to Direct Antimicrobial Pharmacotherapy
105. Antimicrobial Regimen Selection
106. Central Nervous System Infections
107. Lower Respiratory Tract Infections
108. Upper Respiratory Tract Infections
109. Influenza
110. Skin and Soft-Tissue Infections
111. Infective Endocarditis
112. Tuberculosis
113. Gastrointestinal Infections and Enterotoxigenic Poisonings
114. Intra-Abdominal Infections
e115. Parasitic Diseases
116. Urinary Tract Infections and Prostatitis
117. Sexually Transmitted Diseases
118. Bone and Joint Infections
119. Sepsis and Septic Shock
120. Superficial Fungal Infections
121. Invasive Fungal Infections
122. Infections in Immunocompromised Patients
123. Antimicrobial Prophylaxis in Surgery
e124. Travel Health
125. Vaccines and Immunoglobulins
126. Human Immunodeficiency Virus Infection
Section 17 Oncologic Disorders
127. Cancer Treatment and Chemotherapy
128. Breast Cancer
129. Lung Cancer
130. Colorectal Cancer
131. Prostate Cancer
132. Lymphomas
133. Ovarian Cancer
134. Acute Leukemias
135. Chronic Leukemias
136. Multiple Myeloma
e137. Myelodysplastic Syndromes
e138. Renal Cell Carcinoma
139. Melanoma
140. Hematopoietic Stem Cell Transplantation
Section 18 Nutritional Disorders
141. Assessment of Nutrition Status and Nutrition Requirements
142. Parenteral Nutrition
143. Enteral Nutrition
144. Obesity
Index
Foreword
Foreword to the First Edition
Preface
Section 1 Foundation Issues
e1. Health Literacy and Medication Use
e2. Cultural Competency
e3. Medication Safety Principles and Practices
e4. Clinical Pharmacokinetics and Pharmacodynamics
e5. Pharmacogenetics
e6. Pediatrics
e7. Geriatrics
e8. Palliative Care
e9. Clinical Toxicology
e10. Clinical Management of Potential Bioterrorism-related Conditions
Section 2 Cardiovascular Disorders
e11. Cardiovascular Testing
12. Cardiac Arrest
13. Hypertension
14. Chronic Heart Failure
15. Acute Decompensated Heart Failure
16. Stable Ischemic Heart Disease
17. Acute Coronary Syndromes
18. The Arrhythmias
19. Venous Thromboembolism
20. Stroke
21. Dyslipidemia
e22. Peripheral Arterial Disease
23. Use of Vasopressors and Inotropes in the Pharmacotherapy of Shock
24. Hypovolemic Shock
e25. Introduction to Pulmonary Function Testing
Section 3 Respiratory Disorders
26. Asthma
27. Chronic Obstructive Pulmonary Disease
28. Pulmonary Arterial Hypertension
29. Cystic Fibrosis
e30. Drug-Induced Pulmonary Diseases
Section 4 Gastrointestinal Disorders
e31. Evaluation of the Gastrointestinal Tract
32. Gastroesophageal Reflux Disease
33. Peptic Ulcer Disease and Related Disorders
34. Inflammatory Bowel Disease
35. Nausea and Vomiting
36. Diarrhea, Constipation, and Irritable Bowel Syndrome
37. Portal Hypertension and Cirrhosis
e38. Drug-Induced Liver Disease
39. Pancreatitis
40. Viral Hepatitis
41. Celiac Disease
Section 5 Renal Disorders
e42. Evaluation of Kidney Function
43. Acute Kidney Injury
44. Chronic Kidney Disease
45. Hemodialysis and Peritoneal Dialysis
46. Drug-Induced Kidney Disease
47. Glomerulonephritis
48. Drug Therapy Individualization for Patients with Chronic Kidney Disease
49. Disorders of Sodium and Water Homeostasis
50. Disorders of Calcium and Phosphorus Homeostasis
51. Disorders of Potassium and Magnesium Homeostasis
52. Acid-Base Disorders
Section 6 Neurologic Disorders
e53. Evaluation of Neurologic Illness
54. Alzheimer Disease
55. Multiple Sclerosis
56. Epilepsy
57. Status Epilepticus
58. Acute Management of the Brain Injury Patient
59. Parkinson Disease
60. Pain Management
61. Headache Disorders
Section 7 Psychiatric Disorders
e62. Assessment of Psychiatric Disorders
63. Attention Deficit/Hyperactivity Disorder
64. Eating Disorders
65. Substance-Related Disorders I: Overview and Depressants, Stimulants, and Hallucinogens
66. Substance-Related Disorders II: Alcohol, Nicotine, and Caffeine
67. Schizophrenia
68. Major Depressive Disorder
69. Bipolar Disorder
70. Anxiety Disorders: Generalized Anxiety, Panic, and Social Anxiety Disorders
71. Posttraumatic Stress Disorder and Obsessive-Compulsive Disorder
72. Sleep-Wake Disorders
73. Disorders Associated with Intellectual Disabilities
Section 8 Endocrinologic Disorders
74. Diabetes Mellitus
75. Thyroid Disorders
76. Adrenal Gland Disorders
e77. Pituitary Gland Disorders
Section 9 Gynecologic and Obstetric Disorders
78. Pregnancy and Lactation: Therapeutic Considerations
79. Contraception
80. Menstruation-Related Disorders
81. Endometriosis
82. Hormone Therapy in Women
Section 10 Urologic Disorders
83. Erectile Dysfunction
84. Benign Prostatic Hyperplasia
85. Urinary Incontinence
Section 11 Immunologic Disorders
e86. Function and Evaluation of the Immune System
87. Systemic Lupus Erythematosus
e88. Drug Allergy
89. Solid-Organ Transplantation
Section 12 Rheumatologic Disorders
90. Osteoarthritis
91. Rheumatoid Arthritis
92. Osteoporosis and Osteomalacia
93. Gout and Hyperuricemia
Section 13 Ophthalmic and Otolaryngological Disorders
94. Glaucoma
95. Allergic Rhinitis
Section 14 Dermatologic Disorders
96. Acne Vulgaris
97. Psoriasis
98. Atopic Dermatitis
e99. Dermatologic Drug Reactions and Common Skin Conditions
Section 15 Hematologic Disorders
100. Anemias
101. Coagulation Disorders
102. Sickle Cell Disease
e103. Drug-Induced Hematologic Disorders
Section 16 Infectious Diseases
e104. Laboratory Tests to Direct Antimicrobial Pharmacotherapy
105. Antimicrobial Regimen Selection
106. Central Nervous System Infections
107. Lower Respiratory Tract Infections
108. Upper Respiratory Tract Infections
109. Influenza
110. Skin and Soft-Tissue Infections
111. Infective Endocarditis
112. Tuberculosis
113. Gastrointestinal Infections and Enterotoxigenic Poisonings
114. Intra-Abdominal Infections
e115. Parasitic Diseases
116. Urinary Tract Infections and Prostatitis
117. Sexually Transmitted Diseases
118. Bone and Joint Infections
119. Sepsis and Septic Shock
120. Superficial Fungal Infections
121. Invasive Fungal Infections
122. Infections in Immunocompromised Patients
123. Antimicrobial Prophylaxis in Surgery
e124. Travel Health
125. Vaccines and Immunoglobulins
126. Human Immunodeficiency Virus Infection
Section 17 Oncologic Disorders
127. Cancer Treatment and Chemotherapy
128. Breast Cancer
129. Lung Cancer
130. Colorectal Cancer
131. Prostate Cancer
132. Lymphomas
133. Ovarian Cancer
134. Acute Leukemias
135. Chronic Leukemias
136. Multiple Myeloma
e137. Myelodysplastic Syndromes
e138. Renal Cell Carcinoma
139. Melanoma
140. Hematopoietic Stem Cell Transplantation
Section 18 Nutritional Disorders
141. Assessment of Nutrition Status and Nutrition Requirements
142. Parenteral Nutrition
143. Enteral Nutrition
144. Obesity
Index