Colorectal Cancer
Special Topic Issue: Digestive Diseases 2007, Vol. 25, No. 1
1st Edition
Published on 26. March 2007
Book
Paperback/Softback
106 pages
978-3-8055-8272-8 (ISBN)
Description
Over the last three decades, a great deal of progress has been made regarding the genetics, natural history, diagnosis, accurate staging and therapeutic modalities of rectal cancer. This development has led to a substantial improvement in survival and local recurrence rates, exceeding those achieved for colon cancer. Even though surgery remains the cornerstone of the treatment of rectal cancer, research is continued to establish new guidelines for a multimodality treatment resulting in even further improved recurrence and survival rates, and quality of life.
This publication features reviews on current knowledge and treatment trends, ranging from neo-adjuvant chemoradiation and radiotherapy to preoperative staging and the advantages and challenges of a laparoscopic approach. Moreover, in a review of the molecular biological changes characterizing colorectal cancer, the possible implementations of genetic studies in screening and follow-up are discussed. Finally, the issue also includes original articles focusing on various aspects of the management of patients suffering from the disease.
More details
Content
Editorial; Rectal Cancer - Towards Establishing a New Strategy of Treatment: Xynos, E.; Dervenis, C.; Review Articles; Genetic Alterations in Sporadic and Hereditary Colorectal Cancer: Implementations for Screening and Follow-Up: Souglakos, J.; Preoperative Imaging Staging of Rectal Cancer: Karantanas, A.H.; Yarmenitis, S.; Papanikolaou, N.; Gourtsoyiannis, N.; Laparoscopic Approach to Colonic Cancer: Critical Appraisal of the Literature: Fingerhut, A.; Ata, T.; Chouillard, E.; Alexakis, N.; Veyrie, N.; Definition of Total Mesorectal Excision, Including the Perineal Phase: Technical Considerations: Havenga, K.; Grossmann, I.; DeRuiter, M.; Wiggers, T.; Role of Total Mesorectal Excision and of Circumferential Resection Margin in Local Recurrence and Survival of the Patients with Rectal Carcinoma: Tzardi, M.; Neoadjuvant Radiochemotherapy for Rectal Cancer: Vini, L.; Adjuvant Chemotherapy for Colon Cancer: Evidence on Improvement in Survival: Samantas, E.; Dervenis, C.; Rigatos, S.K.; Early Rectal Cancer: Definition and Management: Lezoche, E.; Baldarelli, M.; De Sanctis, A.; Lezoche, G.; Guerrieri, M.; Original Articles; Conventional CT for the Prediction of an Involved Circumferential Resection Margin in Primary Rectal Cancer: Wolberink, S.V.R.C.; Beets-Tan, R.G.H.; de Haas-Kock, D.F.M.; Span, M.M.; van de Jagt, E.J.; van de Velde, C.J.H.; Wiggers, T.; Detection of Colorectal Cancer Hepatic Metastases with Contrast-Enhanced Ultrasound: Comparison with Conventional B-Mode Ultrasound: Yarmenitis, S.D.; Karantanas, A.; Bakantaki, A.; Papantoniou, Y.; Gourtsoyiannis, N.; Lymph Node Clearance after Total Mesorectal Excision for Rectal Cancer: Laparoscopic versus Open Approach: Pechlivanides, G.; Gouvas, N.; Tiaoussis, J.; Tzortzinis, A.; Tzardi, M.; Moutafidis, M.; Dervenis, C.; Xynos, E.; Irinotecan plus Weekly 5-Fluorouracil and Leucovorin as Salvage Treatment for Patients with Metastatic Colorectal Cancer: A Phase II Trial: Souglakos, J.; Vardakis, N.; Androulakis, N.; Kakolyris, S.; Kourousis, C.; Mavroudis, D.; Pallis, A.; Agelaki, S.; Kalbakis, K.; Georgoulias, V.