The Hypothalamus-Pituitary-Adrenal Axis: Volume 7
Volume 7
Published on 7. July 2008
Book
Hardback
416 pages
978-0-444-53040-0 (ISBN)
Description
The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage.
This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease.
This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease.
More details
Series
Language
English
Place of publication
Oxford
United Kingdom
Publishing group
Elsevier Science & Technology
Target group
Professional and scholarly
Immunologists, rheumatologists, endocrinologists, and neuroendocrinologists.
Product notice
sewn/stitched
Paper over boards
Dimensions
Height: 236 mm
Width: 165 mm
Thickness: 23 mm
Weight
862 gr
ISBN-13
978-0-444-53040-0 (9780444530400)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
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Other editions
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Content
Part 1: Physiology - Introduction: The HPA Axis and the Immune system: interactions in perspective; Physiology of the Hypothalamic-Pituitary-Adrenocortical axis; Molecular mechanisms of glucocorticoid signaling; Organization of the sympathetic nervous system; The innate immune system; Specific immune response; The immune system of the brain; Part 2: Effect of the HPA axis and the sympathetic system on the immune system - Glucocorticoid effects on the immune response; Glucocorticoids and dendritic cells: a link between innate and adaptive immunity; Toll-like receptors and glucocorticoids; Effects of glucocorticoids on the developing thymus; Effects of catecholamines on the immune response; Enhancing versus suppressive effects of stress on immune function; Part 3: Effect of the immune response on the HPA axis and the sympathetic nervous system - Processing of cytokine signals at CNS levels: relevance for immune-HPA axis interactions; Inflammatory mediator action on the anterior pituitary gland; Neuroendocrinology and the Immune Response. Inflammatory mediator effects on the adrenal gland; Inflammatory mediators affect the autonomic nervous system; Part 4: Clinical implications of neuro-endocrine-immune interactions - The neuroendocrinology and Immunology of critical illness; Neuroendocrinology of inflammatory disorders; The HPA axis in rheumatic autoimmune disorders; Glucocorticoid resistance in inflammatory diseases; Glucocorticoids and asthma: from clinics to genes