Molecular and Cellular Mechanisms of Toxicity
1st Edition
Published on 14. December 2020
Book
Paperback/Softback
224 pages
978-0-367-22914-6 (ISBN)
Description
First Published in 1995: Written by specialists in their fields, this book contains short reviews intended to highlight points of growing interest in mechanistic toxicology. The first section considers selected aspects of molecular mechanisms, including selectivity of toxic agents and repair processes in the nervous system, toxicity of oxygen, fibers and aflatoxins. The second section discusses the interactions of carcinogens with DNA, and other targets, and their relevance to both molecular dosimetry of exposure and development of cancer. The final part is concerned with cellular and genetic aspects and includes coverage of some of the most recent and rapidly developing problems in toxicology.
More details
Series
Language
English
Place of publication
London
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
Professional and scholarly
Illustrations
7 equations; 4 Halftones, black and white; 23 Tables, black and white
Dimensions
Height: 234 mm
Width: 156 mm
Weight
453 gr
ISBN-13
978-0-367-22914-6 (9780367229146)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Francesco De Matteis
Molecular and Cellular Mechanisms of Toxicity
Book
06/2019
1st Edition
CRC Press
€186.01
Withdrawn from sale
Persons
Francesco De Matteis is a Professor at the Institute of Pharmacology, University of Turin, Italy.
Lewis L. Smith is a Professor at the MRC Toxicology Unit, University of Leicester, England.
Lewis L. Smith is a Professor at the MRC Toxicology Unit, University of Leicester, England.
Content
Mechanisms of Toxicity
1. Aspects of Selectivity and Mechanism in Neurotoxicity
W. N. Aldridge
2. Injury and Repair in Neurotoxicology
Marcello Lotti
3. Toxicity of Oxygen
Donald J. Reed
4. Aflatoxins
Margaret M. Manson
5. Experimental Studies with Fibers
J.M.G. Davis and R.C. Brown
Biomonitoring and Molecular Interactions in Carcinogenesis
6. Biomonitoring and Molecular Dosimetry of Genotoxic Carcinogens
Peter Farmer
7. The Relationship of Molecular Interactions with DNA to Cancer: Scientific Developments
P.N. Magee
Genetic and Cellular Aspects in Toxicology
8. The Study of Genes and Gene Expression by In Situ Hybridization: A Potentially Useful Approach in Toxicology
Ian Lauder
9. Genetic Variation in Human and Laboratory Animal Populations and Its Implications for Toxicological Research and Human Risk Assessment
Michael F. W. Festing
10. Mechanisms of Cell Death, with Particular Reference to Apoptosis
Gerald M. Cohen et al.
11. Apoptosis: Some Aspects of Regulation and Role in Carcinogenesis
Rolf Schulte-Hermann
?
1. Aspects of Selectivity and Mechanism in Neurotoxicity
W. N. Aldridge
2. Injury and Repair in Neurotoxicology
Marcello Lotti
3. Toxicity of Oxygen
Donald J. Reed
4. Aflatoxins
Margaret M. Manson
5. Experimental Studies with Fibers
J.M.G. Davis and R.C. Brown
Biomonitoring and Molecular Interactions in Carcinogenesis
6. Biomonitoring and Molecular Dosimetry of Genotoxic Carcinogens
Peter Farmer
7. The Relationship of Molecular Interactions with DNA to Cancer: Scientific Developments
P.N. Magee
Genetic and Cellular Aspects in Toxicology
8. The Study of Genes and Gene Expression by In Situ Hybridization: A Potentially Useful Approach in Toxicology
Ian Lauder
9. Genetic Variation in Human and Laboratory Animal Populations and Its Implications for Toxicological Research and Human Risk Assessment
Michael F. W. Festing
10. Mechanisms of Cell Death, with Particular Reference to Apoptosis
Gerald M. Cohen et al.
11. Apoptosis: Some Aspects of Regulation and Role in Carcinogenesis
Rolf Schulte-Hermann
?