Molecular Biology of the Neuron
2nd Edition
Published on 19. January 2006
Book
Paperback/Softback
504 pages
978-0-19-850997-4 (ISBN)
Description
Nerve cells - neurons - are arguably the most complex of all cells. From the action of these cells comes movement, thought and consciousness. It is a challenging task to understand what molecules direct the various diverse aspects of their function. This has produced an ever-increasing amount of molecular information about neurons, and only in Molecular Biology of the Neuron can a large part of this information be found in one source. In this book, a non-specialist can learn about the molecules that control information flow in the brain or the progress of brain disease in an approachable format, while the expert has access to a wealth of detailed information from a wide range of topics impacting on his or her field of endeavour. The text is designed to achieve a balance of accessibility and broad coverage with up-to-date molecular detail.
In the six years since the first edition of Molecular Biology of the Neuron there has been an explosion in the molecular information about neurons that has been discovered, and this information is incorporated into this second edition. Entirely new chapters have been introduced where recent advances have made a new aspect of neuronal function more comprehensible at the molecular level. Written by leading researchers in the field, the book provides an essential overview of the molecular structure and function of neurons, and will be an invaluable tool to students and researchers alike.
In the six years since the first edition of Molecular Biology of the Neuron there has been an explosion in the molecular information about neurons that has been discovered, and this information is incorporated into this second edition. Entirely new chapters have been introduced where recent advances have made a new aspect of neuronal function more comprehensible at the molecular level. Written by leading researchers in the field, the book provides an essential overview of the molecular structure and function of neurons, and will be an invaluable tool to students and researchers alike.
Reviews / Votes
It is always difficult to ensure a uniform standard of writing from a diverse group of authors, but these editors seem to have achieved it. Thus, each of the chapters provides a useful review of current knowledge of molecular data relating to neurons . . . will be appreciated by those in clinical systems or cellular neuroscience . . . it is unfair to pick out particular chapters for mention, since all of them are well constructed. * Physiology News, Number 56 *More details
Series
Edition
2nd Revised edition
Language
English
Place of publication
Oxford
United Kingdom
Target group
Professional and scholarly
Post graduate and post-doctoral researchers in the neurosciences. Senior researchers in neuroscience
Edition type
Revised edition
Illustrations
7 halftones, numerous tables and line drawings
Dimensions
Height: 244 mm
Width: 170 mm
Thickness: 27 mm
Weight
854 gr
ISBN-13
978-0-19-850997-4 (9780198509974)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Previous edition
Book
06/1997
Bios Scientific Publishers Ltd
€115.32
Article exhausted; check for reprint
Persons
Edited by Wayne Davies, IBLS, Division of Molecular Genetics, University of Glasgow, Glasgow, UK and Brian Morris, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow, UK
Contributors: Douglas Armstrong, Institute for Adaptive and Neural Computation, University of Edinburgh, Forrest Hill, Edinburgh, UK Jesus Avila, Departamento de Biologia Molecular, Universidad Autonoma de Madrid, Madrid, Spain Mark Bailey, IBLS Division of Molecular Genetics, University of Glasgow, Glasgow, UK Simona Baldassa, Dipartimento di Fisiologia e Biochimia Generali, University of Milan, Milan, Italy Stefan Catsicas, EPFL, Dorigny, Switzerland Flaminio Cattabeni, Dept of Pharmacological Sciences, University of Milan, Milan, Italy Christopher Connolly, Dept of Pharmacology & Neuroscience, University of Dundee, Dundee, UK Wayne Davies, IBLS Division of Molecular Genetics, University of Glasgow, Glasgow, UK Javier Diaz-Nido, Departamento de Biologia Molecular, Universidad Autonoma de Madrid, Madrid, Spain Uwe Ernsberger, Institute for Anatomy & Cell Biology, Ruprecht-Karls-Universitat Heidelberg, Heidelberg, Germany Jean-Antoine Girault, INSERM U536, Institut du Fer a Moulin, Paris, France Thora Glencorse, IBLS division of Molecular Genetics, University of Glasgow, Glasgow, UK Stephen Goodwin, Division of Molecular Genetics, University of Glasgow, Glasgow, UK Giles Hardingham, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK Harald Jockusch, Developmental Biology and Molecular Pathology, University of Bielefeld, Bielefeld, Germany Jennifer Koenig, Dept of Pharmacology, University of Cambridge, Cambridge, UK Brian Morris, Division of Neuroscience & Biomedical Systems, University of Glasgow, Glasgow, UK Mauro Pessia, Isitituto di Ricerche Farmacologiche 'Mario Negri', Santa Maria Imbaro, Italy Thomas Schmitt-John, Developmental Biology and Molecular Pathology, University of Bielefeld, Bielefeld, Germany Paul Shiels, Division of Cancer Sciences & Molecular Pathology, Glasgow Western Infirmary, Glasgow, UK Julie Staple Emmapaola Sturani, Dipartimento di Fisiologia e Biochimia Generali, University of Milan, Milan, Italy Renata Zippel, Dipartimento di Fisiologia e Biochimia Generali, University of Milan, Milan, Italy
Contributors: Douglas Armstrong, Institute for Adaptive and Neural Computation, University of Edinburgh, Forrest Hill, Edinburgh, UK Jesus Avila, Departamento de Biologia Molecular, Universidad Autonoma de Madrid, Madrid, Spain Mark Bailey, IBLS Division of Molecular Genetics, University of Glasgow, Glasgow, UK Simona Baldassa, Dipartimento di Fisiologia e Biochimia Generali, University of Milan, Milan, Italy Stefan Catsicas, EPFL, Dorigny, Switzerland Flaminio Cattabeni, Dept of Pharmacological Sciences, University of Milan, Milan, Italy Christopher Connolly, Dept of Pharmacology & Neuroscience, University of Dundee, Dundee, UK Wayne Davies, IBLS Division of Molecular Genetics, University of Glasgow, Glasgow, UK Javier Diaz-Nido, Departamento de Biologia Molecular, Universidad Autonoma de Madrid, Madrid, Spain Uwe Ernsberger, Institute for Anatomy & Cell Biology, Ruprecht-Karls-Universitat Heidelberg, Heidelberg, Germany Jean-Antoine Girault, INSERM U536, Institut du Fer a Moulin, Paris, France Thora Glencorse, IBLS division of Molecular Genetics, University of Glasgow, Glasgow, UK Stephen Goodwin, Division of Molecular Genetics, University of Glasgow, Glasgow, UK Giles Hardingham, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK Harald Jockusch, Developmental Biology and Molecular Pathology, University of Bielefeld, Bielefeld, Germany Jennifer Koenig, Dept of Pharmacology, University of Cambridge, Cambridge, UK Brian Morris, Division of Neuroscience & Biomedical Systems, University of Glasgow, Glasgow, UK Mauro Pessia, Isitituto di Ricerche Farmacologiche 'Mario Negri', Santa Maria Imbaro, Italy Thomas Schmitt-John, Developmental Biology and Molecular Pathology, University of Bielefeld, Bielefeld, Germany Paul Shiels, Division of Cancer Sciences & Molecular Pathology, Glasgow Western Infirmary, Glasgow, UK Julie Staple Emmapaola Sturani, Dipartimento di Fisiologia e Biochimia Generali, University of Milan, Milan, Italy Renata Zippel, Dipartimento di Fisiologia e Biochimia Generali, University of Milan, Milan, Italy
Content
1. Studying neuronal function using the Drosophila genetic system ; 2. Using mouse genetics to study neuronal development and function ; 3. Gene expression: from precursor to mature neuron ; 4. Protein trafficking in neurons ; 5. Ion channels and electrical activity ; 6. Molecular biology of neurotransmitter release ; 7. Molecular biology of postsynaptic structures ; 8. Signal reception: Ligand-gated ion channel receptors ; 9. Signal reception: G protein-coupled receptors ; 10. Synapse-to-nucleus calcium signalling ; 11. Signalling by tyrosine phosphorylation in the nervous system ; 12. Mature neurons: signal transduction-serine/threonine kinases ; 13. The cytoskeleton ; 14. Neuronal plasticity ; 15. Genetic basis of human neuronal diseases ; 16. Ageing and the death of neurones