
The Evolution of HIV
Keith A. Crandall(Editor)
Johns Hopkins University Press
Published on 21. June 1999
Book
Paperback/Softback
520 pages
978-0-8018-6151-2 (ISBN)
Description
The HIV epidemic has spawned a scientific effort unprecedented in the history of infectious disease research. This effort has merged aspects of clinical research, basic molecular biology, immunology, cell biology, epidemiology, and mathematical biology in ways that have not been seen before. In The Evolution of HIV Keith A. Crandall brings together researchers from these disciplines to present perspectives on both the molecular biology and molecular evolution of HIV. The book is organized into three sections: "Introduction to HIV" explores the fundamentals of the virus's molecular biology and its global diversity. "Molecular Methods for Studying HIV Diversity" looks at such topics as HIV phylogenetics, modeling the molecular evolution of HIV sequences, the use of phylogenetic inference to test an HIV transmission hypothesis, and coalescent approaches to HIV population genetics. The third section,"Case Studies of HIV Evolution" examines the levels of diversity within and among host individuals, the phylogenetics of known transmission histories, and HIV evolution and disease progression via longitudinal studies.
The book will be of interest to researchers and clinicians working on HIV, as well as scientists studying molecular evolution, population genetics, and evolutionary biology. Contributors are John M. Coffin, Keith A. Crandall, Joseph Felsenstein, Walter M. Fitch, Brian Foley, Esther Guzman, Paul H. Harvey, David M. Hillis, Edward C. Holmes, Marcia L. Kalish, Bette T. M. Korber, Julia Krushkal, Carla L. Kuiken, Gerald H. Learn, Thomas Leitner, Wen-Hsiung Li, Francine E. McCutchan, Spencer V. Muse, Oliver G. Pylons, Allen G. Rodrigo, Raj Shankarappa, Richard W. Steketee, Alan R. Templeton, Donald M. Thea, Raphael P. Viscidi, Steven M. Wolinsky.
The book will be of interest to researchers and clinicians working on HIV, as well as scientists studying molecular evolution, population genetics, and evolutionary biology. Contributors are John M. Coffin, Keith A. Crandall, Joseph Felsenstein, Walter M. Fitch, Brian Foley, Esther Guzman, Paul H. Harvey, David M. Hillis, Edward C. Holmes, Marcia L. Kalish, Bette T. M. Korber, Julia Krushkal, Carla L. Kuiken, Gerald H. Learn, Thomas Leitner, Wen-Hsiung Li, Francine E. McCutchan, Spencer V. Muse, Oliver G. Pylons, Allen G. Rodrigo, Raj Shankarappa, Richard W. Steketee, Alan R. Templeton, Donald M. Thea, Raphael P. Viscidi, Steven M. Wolinsky.
Reviews / Votes
As a model for viral evolution, this book is a gold mine. [It] should be used as a starting point for those who want to browse the huge literature on the subject... [and] to those who devise policies for the containment of the epidemic. European Molecular Biology Organization ReportsMore details
Language
English
Place of publication
Baltimore, MD
United States
Target group
College/higher education
Professional and scholarly
Product notice
Paperback (trade)
Illustrations
53 s/w Abbildungen
53 Illustrations, black and white
Dimensions
Height: 229 mm
Width: 154 mm
Thickness: 31 mm
Weight
680 gr
ISBN-13
978-0-8018-6151-2 (9780801861512)
DOI
10.56021/9780801861505
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Keith A. Crandall
The Evolution of HIV
Book
06/1999
Johns Hopkins University Press
€106.05
Article not available for order
Person
Keith A. Crandall is assistant professor of zoology at Brigham Young University.
Content
Contributors
Preface
Part I: Introduction to HIV
Chapter 1. Molecular Biology of HIV
Chapter 2. Global Diversity in HIV
Part II: Molecular Methods For Studying HIV Diversity
Chapter 3. Phylogenetics and the Study of HIV
Chapter 4. Modeling the Molecular Evolution of HIV Sequeuences
Chapter 5. Statistical Approaches to Detecting Recombination
Chapter 6. The Molecular Population Dynamics of HIV-1
Chapter 7. Use of Phylogenetic Inference to Test an HIV Transmission Hypothesis
Chapter 8. Coalescent Approaches to HIV Population Genetics
Part III: Case Studies of HIV Evolution
Chapter 9. Levels of Diversity Within and Among Host Individuals
Chapter 10. The Phylogenetics of Known Transmission Histories
Chapter 11. HIV Evolution and Disease Progression Via Longitudinal Studies
Chapter 12. Perinatal HIV Infection
Chapter 13. Determinants of HIV-1 Protein Evolution
Chapter 14. Evolution of HIV-1 Resistance to Antiviral Agents
Index
Preface
Part I: Introduction to HIV
Chapter 1. Molecular Biology of HIV
Chapter 2. Global Diversity in HIV
Part II: Molecular Methods For Studying HIV Diversity
Chapter 3. Phylogenetics and the Study of HIV
Chapter 4. Modeling the Molecular Evolution of HIV Sequeuences
Chapter 5. Statistical Approaches to Detecting Recombination
Chapter 6. The Molecular Population Dynamics of HIV-1
Chapter 7. Use of Phylogenetic Inference to Test an HIV Transmission Hypothesis
Chapter 8. Coalescent Approaches to HIV Population Genetics
Part III: Case Studies of HIV Evolution
Chapter 9. Levels of Diversity Within and Among Host Individuals
Chapter 10. The Phylogenetics of Known Transmission Histories
Chapter 11. HIV Evolution and Disease Progression Via Longitudinal Studies
Chapter 12. Perinatal HIV Infection
Chapter 13. Determinants of HIV-1 Protein Evolution
Chapter 14. Evolution of HIV-1 Resistance to Antiviral Agents
Index