Protein and Pharmaceutical Engineering
Symposium Proceedings
Published on 1. April 1990
Book
Hardback
198 pages
978-0-471-56771-4 (ISBN)
Description
"Protein and Pharmaceutical Engineering" brings together a distinguished group of experts who scrutinize the architecture and activity of proteins to uncover the underlying principles of macromolecular form and function. Drawing on this knowledge, the contributors to this volume focus on designing and engineering proteins for the development of pharmaceuticals. The authors employ novel approaches in molecular genetics, enzymology, molecular modelling, NMR spectroscopy and X-ray crystallography to reveal the role primary amino acid sequence plays in protein structure and function. Chapters cover areas of research in two broad categories: physical analysis of protein structure and molecular biochemical aspects of protein function.
More details
Series
Language
English
Place of publication
New York
United States
Publishing group
John Wiley and Sons Ltd
Target group
College/higher education
Professional and scholarly
Illustrations
Ill.
Dimensions
Height: 55 mm
Width: 35 mm
Weight
482 gr
ISBN-13
978-0-471-56771-4 (9780471567714)
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Schweitzer Classification
Content
PHYSICAL ANALYSIS OF PROTEIN STRUCTURE: Assignment of Histidine Resonances in the NMR Spectrum of Staphylococcal Nuclease Using Site-Directed Mutagenesis; Detection of Conformational Changes in Active Site Mutants of Staphylococcal Nuclease; The Acetylcholine Receptor; CHEMICAL ASPECTS OF PROTEIN FUNCTION: HIV1 Protease: Bacterial Expression, Purification and Characterization; Stereospecific Catalysis by an Antibody; Enzyme Mimics; Manipulative Mutagenesis of Enzymes.