Cytoskeletal-Membrane Interactions and Signal Transduction
Published on 1. September 1997
Book
Hardback
XVIII, 237 pages
978-3-540-63079-1 (ISBN)
Description
This book brings together current research on the emerging field of cytoskeletal-membrane interactions at cell junctions and the roles of proteins associated with these junctions in signal transduction. It deals principally with two facets of signal transduction: 1) Conventional signal transduction events involving regulation of cadherins and catenins by receptor and non-receptor tyrosine kinases, receptor tyrosine phosphatases, heterotrimeric G proteins PKA and PKC; 2) The involvement of the arm family members such as plakoglobin and beta-catenin, p120 and APC in the Wnt signal transduction pathway.
More details
Series
Language
English
Place of publication
Heidelberg
Germany
Publishing group
Springer Berlin
Target group
College/higher education
Professional and scholarly
Illustrations
3
46 s/w Abbildungen, 4 farbige Abbildungen, 3 s/w Tabellen
6 colour & 44 b&w figures, 3 tables
Weight
600 gr
ISBN-13
978-3-540-63079-1 (9783540630791)
Schweitzer Classification
Content
Cadherins.- Plakoglobin, the other "arm" of vertebrates.- P120ctn: a Src-substrate turned catenin.- Band 6 protein and cytoskeletal organization.- Components of the Wnt signaling pathway.- Glycogen synthase kinase-3.- The role of patterning genes in epidermal differentiation.- Role for the tumor suppressor adenomatous polyposis coli protein in epithelial cell migration and adhesion.- Regulation of cadherin activity by G proteins and the actin cytoskeleton.- Interactions between protein tyrosine phosphatases and cell adhesion molecules.