Botulinum Toxins

List of Contributors vii Treatment of the Periocular Area - Crow's Feet, Brow, and Bunny Lines 165 Girish S. Munavalli, MD (MHS, FACMS), Anthony V. Benedetto, DO (FACP, FCPP), Brian S. Biesman, MD (FACS), and Carolee M. Cutler Peck, MD About the Companion Website xiii Video Table of Contents xv 1 History of Botulinum Toxin for Medical and Aesthetic Use 1 Alastair Carruthers, FRCPC and Jean Carruthers, MD (FRCS(C), FRCOphth) 2 Anatomy and Aesthetic Principles 13 Timothy M. Greco, MD (FACS), Che´rie M. Ditre, MD, and David M. Ozog, MD (FAAD, FACMS) 3 Botulinum Toxin: From Molecule to Medicine 37 Conor J. Gallagher, PhD and Alan Ackerman, PhD 4 Myobloc 53 Neil S. Sadick, MD (FACP, FAAD, FAACS, FACPh) and Suveena Manhas-Bhutani, MD 5 Abobotulinumtoxin: Development and Aesthetic Usage 65 Gary D. Monheit, MD 6 IncobotulinumtoxinA (Xeomin(r)/Bocouture(r)) 79 Ulrich Ku¨hne, MD (DALM) and Matthias Imhof, MD (DALM) 7 Future Injectable Toxins 97 Michael H. Gold, MD 8 Reconstitution, Dilution, Diffusion, and Migration of Botulinum Toxin 109 Murad Alam, MD (MSCI, MBA), Hayes B. Gladstone, MD, and David M. Ozog, MD (FAAD, FACMS) 9 Patient Selection 121 Ryan M. Greene, MD (PhD, FACS), John P. Arkins, BS, and Steven H. Dayan, MD (FACS) 10 Treatment of the Glabella 133 Neal D. Varughese, MD (MBA) and David J. Goldberg, MD (JD) 11 Treatment of the Forehead 147 Joel L. Cohen, MD (FAAD, FACMS) and Ramin Fathi, MD 12 Treatment of the Periocular Area - Crow's Feet, Brow and Bunny Lines Girish S. Munavalli, MD(MHS, FACMS), Antony V. BEnedetto, DO (FACP, FCPP), Brian S. Biesman, MD (FACS), and Carolee M. Cutler Peck, MD 13 Contouring of the Lower Face and of the Lower Leg and Calf 177 Mee young Park, MD (PhD), Dennis A. Porto, MD, and Ki Young Ahn, MD (PhD) 14 Treatment of the Perioral Area 191 Shawn Allen, MD (FAAD, FACMS), Roberta Sengelmann, MD, and Rachel Simmons, MD (FAAD) 15 Neck Rejuvenation 199 Koenraad De Boulle, MD, Lakhdar Belhaouari, MD, and Julia D. Kreger, MD 16 Correction of Facial Asymmetry 213 Scott Rickert, MD (FACS), Lesley F. Childs, MD, and Andrew Blitzer, MD (DDS, FACS) 17 Complications and Diffusion 221 Matteo C. LoPiccolo, MD, Farhaad R. Riyaz, MD, and David M. Ozog, MD (FAAD, FACMS) 18 Combination Therapy of Botulinum Toxin with other Nonsurgical Procedures 233 Amy Forman Taub, MD and Lauren Fine, MD (FAAD) 19 Peri-Procedure Botulinum Toxin for Skin Cancer Patients and Scars 253 Timothy Corcoran Flynn, MD, Molly C. Powers, MD, and David M. Ozog, MD (FAAD, FACMS) 20 Achieving a Natural Look 263 Doris Hexsel, MD, Camile L. Hexsel, MD (FAAD, FACMS), and Carolina Siega, BSc 21 Special Considerations in Darker Skin 275 Chere´ Lucas Anthony, MD and Marta I. Rendon, MD (FAAD, FACP) 22 Axillary Hyperhidrosis 285 Ada Regina Trindade de Almeida, MD, Joel L. Cohen, MD (FAAD, FACMS), and Chinobu Chisaki, MD 23 Primary Focal Palm, Sole, Craniofacial, and Compensatory Hyperhidrosis 299 Dee Anna Glaser, MD and Adam R. Mattox, DO (MS) 24 Topical Botulinum Toxin 317 Richard G. Glogau, MD and Eileen Axibal, MD 25 Exciting New Uses of Botulinum Toxin Type A: Dermatology/Dermatologic Surgery and Beyond 329 Donna Bilu Martin, MD (FAAD) and Stephen Mandy, MD (FAAD) 26 Modulating Affect and Mood with Botulinum Toxin Injections: Psychosocial Implications of Neuromodulators 345 James L. Griffith, MD (MSci), Kevin C. Smith, MD (FRCPC (DERM)), and Murad Alam, MD (MSCI, MBA) 27 OnabotulinumtoxinA (Botox(r)) in Dermatology 357 Jason J. Emer, MD, Eileen Axibal, MD, Ellen S. Marmur, MD (FAAD), and Heidi Waldorf, MD Index 369