Transgenesis Techniques

Name: Transgenesis Techniques | Principles and Protocols
Brand: Humana Press Inc.
Price: 90.9 EUR
Availability: OutOfStock

Principles and Protocols

Alan R. Clarke(Editor)

Humana Press Inc.

2nd Edition

Published on 1. January 2002

Book

Hardback

X, 351 pages

978-0-89603-696-3 (ISBN)

€90.90incl. 7% vat

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Description

The past decade has witnessed a spectacular explosion in both the devel- ment and use of transgenic technologies. Not only have these been used to aid our fundamental understanding of biologic mechanisms, but they have also faci- tated the development of a range of disease models that are now truly beginning to impact upon our approach to human disease. Some of the most exciting model systems relate to neurodegenerative disease and cancer, where the availability of appropriate models is at last allowing radically new therapies to be developed and tested. This latter point is of particular significance given the current concerns of the wider public over both the use of animal models and the merits of using genetically modified organisms. Arguably, advances of the greatest significance have been made using mammalian systems-driven by the advent of embryonic stem-cell-based strategies and, more recently, by cloning through nuclear transfer. For this reason, this new edition of Transgenesis Techniques focuses much more heavily on manipulation of the mammalian genome, both in the general discussions and in the provision of specific protocols.

Reviews / Votes

From Reviews of the First Edition a must in any laboratory - Cellular and Molecular Biology should be useful to anyone currently involved in using transgenesis as a technique - Journal of Heredity Second Edition: ...the book remains an impressive and interesting book that will be a useful reference to molecular and developmental geneticists at all levels and potential tool for teaching graduate students and advanced undergraduates. - Human Genetics It will provide a valuable source of information. It will also remind you of the enormous potential that transgenesis has to offer the biologist. Transgenic research will underpin many future applications from evaluating viral vectors for gene therapy and vaccination to bioreactors for the production of proteins, from models of disease to screening tools for biological activity, from genome mapping to gene function. This book details protocols to let you participate in this. Cloning and Stem Cells

From Reviews of the First Edition a must in any laboratory - Cellular and Molecular Biology should be useful to anyone currently involved in using transgenesis as a technique - Journal of Heredity Second Edition: ...the book remains an impressive and interesting book that will be a useful reference to molecular and developmental geneticists at all levels and potential tool for teaching graduate students and advanced undergraduates. - Human Genetics It will provide a valuable source of information. It will also remind you of the enormous potential that transgenesis has to offer the biologist. Transgenic research will underpin many future applications from evaluating viral vectors for gene therapy and vaccination to bioreactors for the production of proteins, from models of disease to screening tools for biological activity, from genome mapping to gene function. This book details protocols to let you participate in this. Cloning and Stem Cells

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