Transacting Functions of Human Retroviruses
Published on 19. June 1995
Book
Hardback
IX, 243 pages
978-3-540-57901-4 (ISBN)
Description
The coding domains of simple retrovirus genomes direct the synthesis of virion proteins. Complex retroviral genomes generate in addition to virion proteins regulatory transacting proteins that are translated from multiple spliced messenger RNAs and fulfill important functions in the virus life cycle. All human retroviruses have such complex genomes. The transacting proteins of these pathogens are attractive targets for therapeutic intervention because they are viral specific, are essential for efficient virus replication and may be mediators of viral pathogenicity. In summarizing the current knowledge on the regulatory transacting proteins of human retroviruses, this volume makes an important contribution toward the control of virus disease.
More details
Series
Language
English
Place of publication
Heidelberg
Germany
Publishing group
Springer Berlin
Target group
College/higher education
Professional and scholarly
Illustrations
28 s/w Abbildungen
28 black & white illustrations, biography
Dimensions
Height: 23.5 cm
Width: 15.5 cm
Weight
510 gr
ISBN-13
978-3-540-57901-4 (9783540579014)
DOI
10.1007/978-3-642-78929-8
Schweitzer Classification
Other editions
Additional editions
Irvin S.Y. Chen | Hilary Koprowski | A. Srinivasan
Transacting Functions of Human Retroviruses
Book
08/2014
Springer
€106.99
Shipment within 7-9 days
Irvin S.Y. Chen | Hilary Koprowski | A. Srinivasan
Transacting Functions of Human Retroviruses
E-Book
12/2012
Springer
€96.29
Available for download
Content
List of Contents.- Regulation of Foamy Virus Gene Expression.- Transactivation of Cellular Genes by Human Retroviruses.- Regulation of Human Immunodeficiency Virus Type 1 Gene Expression by the Transactivator Protein Tat.- HTLV-1 Oncoprotein Tax and Cellular Transcription Factors.- The Human Immunodeficiency Virus Type 1 Rev Protein: A Pivotal Protein in the Viral Life Cycle.- The Human Immunodeficiency Virus Type 1 Vpu Protein: Roles in Virus Release and CD4 Downregulation.- Viral Protein X.- The Pathogenic Role of Human Immunodeficiency Virus Accessory Genes in Transgenic Mice.- The Human Immunodeficiency Virus Type 1 vif Gene: The Road from an Accessory to an Essential Role in Human Immunodeficiency Virus Type 1 Replication.- Nef.- The vpr Regulatory Gene of Human Immunodeficiency Virus.