Origins of Depression
Report of the Dahlem Workshop on the Origins of Depression: Current Concepts and Approaches Berlin 1982, Oct.31 - Nov. 5
1st Edition
Published on 1. September 1983
Book
Hardback
484 pages
978-3-540-12451-1 (ISBN)
Description
3 and a fraction mayor may not respond to treatment. On the behavioral level, animal research shows that a variety of experimental conditions can induce de- pression. The same is true in the field of treatment, where pharmacologically highly different drugs can equally alleviate depression in animals and hu- mans. The question as to whether this is due to a heterogeneity of depressive subjects based on different pathogenetic mechanisms is open to discussion. We can look for common features of all possible causal factors in the hope of finding a single basic mechanism. Many divergent findings may also be ex- plained as peripheral changes of a highly complicated dynamic system. In the field of psychopharmacology, a circular reasoning has become evident in the sense that originally the clinical antidepressive response was founded on empirical grounds only. In a second step, an attempt was made to characterize some clinically active compounds pharmacologically, and in a third, further compounds were developed based on aspects of the pharmaco- logical profiles.
Moreover, the post hoc development of a pharmacological screening method has the serious disadvantage of delaying breakthroughs into new fields.
Moreover, the post hoc development of a pharmacological screening method has the serious disadvantage of delaying breakthroughs into new fields.
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Series
Language
English
Place of publication
Berlin
Germany
Publishing group
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Target group
Professional and scholarly
Research
Illustrations
biography
Weight
760 gr
ISBN-13
978-3-540-12451-1 (9783540124511)
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J. Angst | A. Carlsson | B.J. Carroll
The Origins of Depression: Current Concepts and Approaches
Report of the Dahlem Workshop on The Origins of Depression: Current Concepts and Approaches Berlin 1982, Oct.31 - Nov. 5
E-Book
12/2012
1st Edition
Springer
€96.29
Available for download
J. Angst | A. Carlsson | B.J. Carroll
The Origins of Depression: Current Concepts and Approaches
Report of the Dahlem Workshop on The Origins of Depression: Current Concepts and Approaches Berlin 1982, Oct.31 - Nov. 5
Book
11/2011
Springer
€106.99
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Persons
Content
The Scope of Depression.- The Epidemiology of Bipolar and Nonbipolar Depression: Rates and Risks.- Depression and Affective Disorder in Later Life.- Gender and Depression.- Recent Life Events and Depression.- Vulnerability to Depression: The Lack of Social Support Does Not Cause Depression.- Stress, Conflict, and Depression.- Separation Models and Depression.- Learned Helplessness - An Animal Model Revisited.- Neurobiologic Dimensions of Depression and Mania.- Current Status of Genetic Research in Affective Disorders.- Neuroendocrine Function in Depression.- Opioid Systems and the Regulation of Mood: Possible Significance in Depression?.- Neurophysiologic Studies of Depression: State of the Art.- Chronobiology of Depression.- New Research Techniques for Studying the Functional Anatomy of Depression.- Depression and Altered Neurotransmission - States, Traits, and Interactions.- Pharmacological Models of Depression.- Heuristically Important Mood-altering Drugs.- Mode of Action of Antidepressant Drugs - Primary Effects.- Mode of Action of Antidepressant Agents and ECT - Adaptive Changes After Subchronic Treatment.- Risk Factors Group Report.- Animal Models Group Report.- Functional Indices of Biological Disturbance Group Report.- Neurotransmission Group Report.- List of Participants.- Author Index.