The Genetics of Male Infertility
Published on 19. January 2011
Book
Paperback/Softback
XVI, 337 pages
978-1-61737-811-9 (ISBN)
Description
Infertility is a common and severe health problem affecting roughly 7% of the male population. It is likely that the majority of those patients have genetic abnormalities that are the cause of their infertility. In The Genetics of Male Infertility, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments.
This volume gives special attention to the significant technological advances in the treatment of male infertility, including intracytoplasmic injection (ICSI) in conjunction with in vitro fertilization (IVF). In addition, new tools discussed include in vitro methodologies, in silico technologies, and new model organisms.
Providing a review of our current understanding of genetic causes of male infertility, The Genetics of Male Infertility serves as a guide to evidence-based clinical applications, and a preview of future possibilities.
This volume gives special attention to the significant technological advances in the treatment of male infertility, including intracytoplasmic injection (ICSI) in conjunction with in vitro fertilization (IVF). In addition, new tools discussed include in vitro methodologies, in silico technologies, and new model organisms.
Providing a review of our current understanding of genetic causes of male infertility, The Genetics of Male Infertility serves as a guide to evidence-based clinical applications, and a preview of future possibilities.
More details
Edition
1st ed. Softcover of orig. ed. 2007
Language
English
Place of publication
Totowa
United States
Target group
Professional and scholarly
Professional/practitioner
Illustrations
47 s/w Abbildungen
XVI, 337 p. 47 illus.
Dimensions
Height: 229 mm
Width: 152 mm
Thickness: 20 mm
Weight
516 gr
ISBN-13
978-1-61737-811-9 (9781617378119)
DOI
10.1007/978-1-59745-176-5
Schweitzer Classification
Other editions
Additional editions
Douglas T. Carrell
The Genetics of Male Infertility
Book
11/2006
Humana Press Inc.
€160.49
Shipment within 15-20 days
Content
Methods and Tools for the Study.- The Genetics of Male Infertility in the Era of Genomics.- The Use of cDNA Libraries to Demonstrate a Linkage Between Transcription and Translation in Male Germ Cells.- Considerations When Using Array Technologies for Male Factor Assessment.- Microarray Analysis of a Large Number of Single-Nucleotide Polymorphisms in Individual Human Spermatozoa.- Physiological and Proteomic Approaches to Understanding Human Sperm Function.- Genetics of Idiopathic Male Infertility.- Meiosis and Errors of Meiosis.- The Immunocytogenetics of Human Male Meiosis.- The Clinical Relevance of Sperm Aneuploidy.- DNA Repair Genes and Genomic Instability in Severe Male Factor Infertility.- The Y Chromosome, Development Spermatogenesis, and Sperm Maturation.- Germ Cell-Specific Genes and Posttranscriptional Regulation in the Testis.- The Genetics of Cryptorchidism.- The Chromatoid Body and microRNA Pathways in Male Germ Cells.- Sperm Maturation in the Epididymis.- Clinical Applications of the Study of the Genetics of Male Infertility.- The Structure of the Y Chromosome and Its Role in Male Infertility.- Y Chromosome Microdeletions and Haplotypes.- The Genetics of Male Infertility.- The Future of the Diagnosis of Male (In) Fertility.- Polymorphisms and Male Infertility.- The Genetics of Abnormal Protamine Expression.- Chromatin Damage and Male Infertility.- Clinical Evaluation of the Genetics of Male Infertility.