Inflammation in the Intestinal Tract: Pathogenesis and Treatment
Falk Symposium 169, Kiev, May 2009. Special Topic Issue: Digestive Diseases 2009, Vol. 27, No. 4
1st Edition
Published on 5. November 2009
Book
Paperback/Softback
176 pages
978-3-8055-9282-6 (ISBN)
Description
The most common forms of chronic inflammatory intestinal diseases, better known as IBD, are ulcerative colitis and Crohn's disease. Their treatment is often challenging due to severe symptoms particularly in young patients and the increasingly complex treatment modalities available. Recent research resulted in a better understanding of the genetic basis of IBD, its relationship with the intestinal microflora, and the role of epithelial cells and the mucosal immune system in its pathogenesis. Prompted by these findings, a general interpretation is emerging of IBD as a multifactorial disturbance of mucosal homeostasis leading to hyperresponsiveness of both the innate and the adaptive elements of the mucosal immune system. This in turn has also led to the development of more specific and effective therapeutic options. During the international Falk symposium held in Kiev in May 2009, a panel of internationally renowned basic and clinical scientists met to discuss various aspects of chronic inflammatory intestinal diseases. This publication contains their papers and represents an in-depth review of current research and clinical management of IBD.
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H.J. Buhr | N.V. Kharchenko | B. Siegmund
Inflammation in the Intestinal Tract: Pathogenesis and Treatment
Falk Symposium 169, Kiev, May 2009. Special Topic Issue: Digestive Diseases 2009, Vol. 27, No. 4
Online / Databases
11/2009
1st Edition
S. Karger
€73.80
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Content
Preface: Zeitz, M.; Pathogenesis of IBD; The Genetic Basis of Inflammatory Bowel Disease: Cooney, R.; Jewell, D.; Mechanisms and Functional Implications of Intestinal Barrier Defects: Shen, L.; Su, L.; Turner, J.R.; Therapeutic Options to Modulate Barrier Defects in Inflammatory Bowel Disease: Hering, N.A.; Schulzke, J.-D.; Inflammation in the Intestinal Tract: Pathogenesis and Treatment: Blumberg, R.S.; Targeted Therapies in Inflammatory Bowel Disease: Siegmund, B.; Diagnostic Approach in IBD; Mucosal Healing: Impact on the Natural Course or Therapeutic Strategies: Vatn, M.H.; Diagnostic Approach to Small Bowel Involvement in Inflammatory Bowel Disease: View of the Endoscopist: Papadakis, K.A.; Significance of Abdominal Ultrasound in Inflammatory Bowel Disease: Dietrich, C.F.; Differential Diagnosis of Chronic Diarrhea; New Insights into Whipple's Disease - A Rare Intestinal Inflammatory Disorder: Marth, T.; Clinical Manifestation of IBD; Joint Extraintestinal Manifestations in Ulcerative Colitis: Dorofeyev, A.E.; Vasilenko, I.V.; Rassokhina, O.A.; Joint Involvement Associated with Inflammatory Bowel Disease: De Vos, M.; Can We Modulate the Clinical Course of Inflammatory Bowel Diseases by Our Current Treatment Strategies?: Cosnes, J.; Primary Sclerosing Cholangitis: A Clinical Case: Gubergrits, N.B.; Surveillance and Screening of Primary Sclerosing Cholangitis: Fouly, A.E.; Dechene, A.; Gerken, G.; Treatment Algorithms in IBD (1); Medical Management of Crohn's Disease: Treatment Algorithms 2009: Hanauer, S.B.; Medical Management of Ulcerative Colitis: Rogler, G.; Diagnostic and Treatment Algorithms of Ulcerative Colitis in Ukraine: Skrypnyk, I.N.; Therapy- and Non-Therapy-Dependent Infectious Complications in Inflammatory Bowel Disease: Epple, H.-J.; Treatment Algorithms in IBD (2); Laparoscopic Management of Inflammatory Bowel Disease: Rosenthal, R.J.; Bashankaev, B.; Wexner, S.D.; Treatment Algorithms in the Case of Perianal Complications of Crohn's Disease: Lozynskyy, Y.S.; Malignant Transformation in IBD: Prevention - Surveillance - Treatment; Malignant Transformation in Inflammatory Bowel Disease: Prevention, Surveillance and Treatment - New Techniques in Endoscopy: Bojarski, C.; Diagnostic Standards in the Pathology of Inflammatory Bowel Disease: Loddenkemper, C.; Malignant Transformation in Inflammatory Bowel Disease - Surveillance Guide: Stallmach, A.; Bielecki, C.; Schmidt, C.