
AIDS Epidemiology
A Quantitative Approach
Oxford University Press Inc
Published on 10. March 1994
Book
Hardback
376 pages
978-0-19-507641-7 (ISBN)
Description
AIDS has appeared in more than 130 countries, and over 100,000 cases of AIDS have been reported in the U.S. alone. More and more, the public will be depending on statisticians to provide answers about the future course of this epidemic.
This comprehensive work confronts the problems that are unique to AIDS research and unites them under a single conceptual framework. It focuses on methods for the design and analysis of epidemiologic studies, the natural history of AIDS and the transmission of HIV, methods for tracking and projecting the course of the epidemic, and statistical issues in therapeutic trials. The various methods of monitoring and forecasting this disease receive comprehensive treatment. These methods include back-calculation, which the authors developed; interpretation of survey data on HIV prevalence; mathematical models for HIV transmission; and approaches that combine different types of epidemiological data. Much of this material -- such as a discussion of methods for assessing safety of the blood supply, an evaluation of survey approaches, and methods to project paediatric AIDS incidence -- is not available in any other work.
This is an essential purchase for all AIDS investigators and epidemiologists.
This comprehensive work confronts the problems that are unique to AIDS research and unites them under a single conceptual framework. It focuses on methods for the design and analysis of epidemiologic studies, the natural history of AIDS and the transmission of HIV, methods for tracking and projecting the course of the epidemic, and statistical issues in therapeutic trials. The various methods of monitoring and forecasting this disease receive comprehensive treatment. These methods include back-calculation, which the authors developed; interpretation of survey data on HIV prevalence; mathematical models for HIV transmission; and approaches that combine different types of epidemiological data. Much of this material -- such as a discussion of methods for assessing safety of the blood supply, an evaluation of survey approaches, and methods to project paediatric AIDS incidence -- is not available in any other work.
This is an essential purchase for all AIDS investigators and epidemiologists.
Reviews / Votes
They have accomplished their goals with a very clearly written, comprehensive, and well organized book. This book should be read by all health professionals who need to understand the quantitative aspects of HIV/AIDS epidemics. It will also be a valuable reference book for anyone involved with clinical or epidemiological studies of HIV/AIDS. * Dr Chin, University of California * This volume presents the contributions that statistical science can make toward current studies in the prevention and control of diseases caused by the Human Immunodeficiency Virus (HIV), as well as estimating the magnitude and future course of the HIV epidemic ... the author thoroughly examine methods for monitoring and predicting the scope of the AIDS epidemic. * American Journal of Public Health, September 1994, Vol. 84, No. 9 * the authors of the book under review here became the John Graunts of the HIV epidemic ... Working closely with the CDC, they were involved in the development of many of the statistical methods used in the analysis of HIV/AIDS data ... This book gives a careful description of these methods. In addition, it gives much of the quantitative history of the epidemic in the United States ... should be of particular interest to biostatisticians and epidemiologists who deal with epidemiological data, but should also be of interest to infectious disease scientists who are not necessarily quantitatively oriented. I would recommend the book both as a text and as a reference. * Ira M. Longini Jr., Emory University School of Public Health, Science, Vol. 265, September 1994 * an impressive and authoritative account of the subject ... While the book is addressed to specialists, a general statistical reader who has not followed work on AIDS is likely to be interested and impressed by the wide range of ideas, techniques and special methods involved * D R Cox, Nuffield College, Pub of International Statistical Institute * This book draws together the wide range of work undertaken by the authors on the statistical analysis of data on the human immunodeficiency virus ... drawing together an impressive amount of data with statistical methods for their analysis, while highlighting the many problems in interpreting results ... this book provides a clear and readable review of the statistical methods used to gain a better understanding of the AIDS epidemic, which will be useful to both epidemiologists and statisticians. * Azra Ghani, St Mary's Hospital Medical School, London, JRSS, Series A, Vol. 158, part 2, 1995 *More details
Series
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Illustrations
line figures and tables
Dimensions
Height: 240 mm
Width: 161 mm
Thickness: 25 mm
Weight
722 gr
ISBN-13
978-0-19-507641-7 (9780195076417)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Persons
Author
Associate Professor of BiostatisticsAssociate Professor of Biostatistics, Johns Hopkins University
Senior InvestigatorSenior Investigator, National Cancer Institute
Content
1: Introduction
2: Risk Factors for Infection and the Probability of HIV Transmission
3: Surveys for Seroprevalence and Seroincidence
4: The Incubation Period Distribution
5: Cofactors and Markers
6: Screening and Accuracy of Tests for HIV
7: Statistical Issues in Surveillance of AIDS Incidence
8: Back-Calculation
9: Epidemic Transmission Models
10: Synthesizing Data Sources and Methods for Assessing the Scope of the Epidemic
11: Developing and Evaluating New Therapies and Vaccines
2: Risk Factors for Infection and the Probability of HIV Transmission
3: Surveys for Seroprevalence and Seroincidence
4: The Incubation Period Distribution
5: Cofactors and Markers
6: Screening and Accuracy of Tests for HIV
7: Statistical Issues in Surveillance of AIDS Incidence
8: Back-Calculation
9: Epidemic Transmission Models
10: Synthesizing Data Sources and Methods for Assessing the Scope of the Epidemic
11: Developing and Evaluating New Therapies and Vaccines