
Engineering of Functional Skeletal Tissues
Springer (Publisher)
Published on 27. November 2014
Book
Paperback/Softback
XVIII, 178 pages
978-1-4471-6122-6 (ISBN)
Description
The science of bone replacement has greatly advanced in recent decades, but replacing bone with bone tissue rather than with metallic components remains in early development. The current volume, third in the series Topics in Bone Biology, deals with problems inherent in inducing the body cells to accomplish bone tissue repair, to degrade devices introduced to provide initial mechanical support, and to attract and stimulate bone f- mation. It is therefore logical that Chapter 1, by Hicok and Hedrick, deals with stem cells, i. e. , pluripotential cells that may differentiate into cartilage and bone cells. The chapter begins with a description of how stem cells may be harvested; the limitations of autologous, embryonic, and adult stem cells; and the need to expand the harvested cells in culture. The authors then discuss the in? uences of the body environment on implanted cells and on the scaffolds that need to be introduced. They emphasize the need for adequate oxygenation and for rapid integration with the vascular system of the host/patient. Stem-cell-engineered cartilage is discussed at some length, along with the need for stem-cell-engineered ligaments and tendons. The chapter concludes with an analysis of what needs to be learned to make stem-cell-engineered bone tissue a reality. In Chapter 2, Gerstenfeld and colleagues review osteogenic growth factors and cytokines, soluble proteins that regulate postnatal bone repair. These molecules are of importance because many are targets of efforts to promote therapeutic bone healing and repair.
More details
Series
Edition
2007 ed.
Language
English
Place of publication
London
United Kingdom
Target group
Professional and scholarly
Professional/practitioner
Illustrations
XVIII, 178 p.
Dimensions
Height: 254 mm
Width: 178 mm
Thickness: 11 mm
Weight
380 gr
ISBN-13
978-1-4471-6122-6 (9781447161226)
DOI
10.1007/978-1-84628-366-6
Schweitzer Classification
Other editions
Additional editions

Felix Bronner | Mary C. Farach-Carson | Antonios G. Mikos
Engineering of Functional Skeletal Tissues
E-Book
03/2007
1st Edition
Springer
€213.99
Available for download

Felix Bronner | Mary C. Farach-Carson | Antonios G. Mikos
Engineering of Functional Skeletal Tissues
Book
12/2006
Springer
€213.99
Shipment within 15-20 days
Content
Stem Cells and the Art of Mesenchymal Maintenance.- Osteogenic Growth Factors and Cytokines and Their Role in Bone Repair.- Bone Allograft Safety and Performance.- Biodegradable Orthopedic Implants.- Titanium Fiber Mesh: A Nondegradable Scaffold Material.- Engineering Polymeric Scaffolds for Bone Grafts.- Injectable Scaffolds for Bone and Cartilage Regeneration.- Motion and Bone Regeneration.- Dental Applications of Bone Biology.- Multiscale Computational Engineering of Bones: State-of-the-Art Insights for the Future.