Multiple Sclerosis
Clinician's Guide to Diagnosis and Treatment
2nd Edition
Published on 23. May 2013
Book
Paperback/Softback
164 pages
978-0-19-984078-6 (ISBN)
Description
Multiple Sclerosis (MS) is an inflammatory, often progressive, and potentially disabling disease of the central nervous system. Onset of disease is usually between the ages of 15 and 50, with the incidence nearly twice as high in women. While the cause of MS is still unknown, the predominant theory is that it is an autoimmune disease, triggered by an unknown environmental factor that results in both loss of central nervous system myelin and degeneration of axons and neurons. Although there have been a number of publications addressing different aspects of MS treatment in the neurological literature, there is a dearth of material on MS designed for internists and primary care physicians, who are often the first to see patients presenting with symptoms of MS. Therefore, this concise, clinically focused volume will serve as a valuable resource tailored to the specific needs of internists and primary care physicians.
Part of the Oxford Neurology Library, this highly practical pocketbook covers current approaches and new developments in the diagnosis, treatment and management of MS, including both early and advanced stages of the disease. The book offers in-depth coverage of special populations, as well as the more unusual manifestations of MS, which are less familiar to the internal medicine audience. It will also address the role of imaging studies in the diagnosis, differential diagnosis and monitoring of the progression of MS. In addition to providing up-to-date information on pharmacological therapies for MS, the book also describes an array of non-pharmacological treatment options.
Part of the Oxford Neurology Library, this highly practical pocketbook covers current approaches and new developments in the diagnosis, treatment and management of MS, including both early and advanced stages of the disease. The book offers in-depth coverage of special populations, as well as the more unusual manifestations of MS, which are less familiar to the internal medicine audience. It will also address the role of imaging studies in the diagnosis, differential diagnosis and monitoring of the progression of MS. In addition to providing up-to-date information on pharmacological therapies for MS, the book also describes an array of non-pharmacological treatment options.
More details
Series
Edition
2nd Revised edition
Language
English
Place of publication
New York
United States
Target group
Professional and scholarly
Edition type
Revised edition
Dimensions
Height: 203 mm
Width: 127 mm
Thickness: 9 mm
Weight
186 gr
ISBN-13
978-0-19-984078-6 (9780199840786)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
E-Book
04/2013
2nd Edition
OUP eBook
€33.99
Available for download
Person
Director, Multiple Sclerosis Treatment and Research Center, Minneapolis Clinic of Neurology, Clinical Profesor of Neurology, University of Minnesota School of Medicine, Minneapolis, Minnesota
Author
Director, Multiple Sclerosis Treatment and Research Center, Minneapolis Clinic of Neurology, and Clinical Professor of NeurologyDirector, Multiple Sclerosis Treatment and Research Center, Minneapolis Clinic of Neurology, and Clinical Professor of Neurology, University of Minnesota School of Medicine, Minneapolis, MN, USA
Content
Introduction ; 1. A Brief History of Multiple Sclerosis ; a.Experimental Autoimmune Encephalomyelitis ; 2. Factors Involved in Causing Multiple Sclerosis ; a.Epidemiology ; b.Causes of MS ; c.Immunology ; 3. The Patterns and Pathophysiology of ; Multiple Sclerosis ; a.Patterns of MS ; b.Pathophysiology of MS ; 4. Imaging of the Central Nervous System ; in Multiple Sclerosis ; a.Standard X-Ray Imaging of the Skull and Spinal Columns ; b.Computed Tomography (CT) Imaging of the CNS ; c.Magnetic Resonance Imaging ; 5. Making a Diagnosis of Multiple Sclerosis ; a.Patterns of Disease Presentation ; b.Demographics ; c.Genetics of MS ; d.Initial Clinical Symptoms in Persons with Relapsing-Remitting MS ; e.Initial Clinical Symptoms of Primary-Progressive MS ; f.Presenting Signs in MS ; g.Magnetic Resonance Imaging ; h.Evoked Responses ; i.Cerebrospinal Fluid Analysis ; j.Ruling Out "MS Look-alikes" ; k.Algorithms for the Diagnosis of MS ; l.Imparting a Diagnosis of MS ; 6. Complications and Comorbidities of Multiple Sclerosis ; a.Loss of Bone Density (Osteopenia or Osteoporosis) ; b.Sleep Apnea and Other Altered Sleep Patterns ; c.Mood Disturbances ; d.Urinary Tract and Other Infections ; e.Sexual Dysfunction ; f.Skin Lesions ; g.Joint Dysfunction ; h.Obesity ; 7. Relapses of Multiple Sclerosis and Their Treatment ; a.What Constitutes a Relapse? ; b.Conventional Relapse Treatments ; c.Unconventional Relapse Treatments ; d.Relapse Prevention ; 8. Long-Term Disease-Modifying Therapies ; a.Issues with Long-Term Immune-Modulating Therapies ; b.Beta-Interferons ; c.Glatiramer Acetate ; d.Second-Line Disease-Modifying Therapies ; e.When Should Long-Term Immune-Modulating Therapy Be Stopped? ; f.Future Therapies ; 9. Management of Multiple Sclerosis Symptoms ; a. Fatigue ; b.Depression ; c.Pain ; d.Spasticity ; e.Sexual Dysfunction ; f.Conclusion ; 10. Complementary Therapies for Multiple Sclerosis ; a.Physical Therapy ; b.Exercise Physiologists ; c.Occupational Therapy ; d.Psychiatrists, Counselors, and Psychologists ; e.Neuropsychologists ; f.Orthotists ; g.Neuro-Ophthalmologists ; h.Urologists ; i.Social Workers ; j.Diet, Nutrition, and Food Supplements ; 11. Gender Issues and Special Multiple Sclerosis ; Populations ; a.Women ; b. Men ; c.Children of Parents with MS ; d.Pediatric MS ; 12. Resources ; a.Web Sites ; b.Patient Advocacy Organizations ; c.Sites for Disease-Modifying Therapies ; d.Site for MR Imaging Protocol for MS ; e.Patient Books and Materials ; Index