Principles of Tumors
A Translational Approach to Foundations
2nd Edition
Published on 1. November 2019
Book
Paperback/Softback
686 pages
978-0-12-816920-9 (ISBN)
Description
Principles of Tumors: A Translational Approach to Foundations, Second Edition, provides a concise summary of translational/interdisciplinary topics on the various aspects of tumors, especially abnormalities in their cells, their causes and effects on patients. Topics discussed include how genomic abnormalities in tumors may result from the actions of carcinogens and how genomic changes determine the cell biological/morphological abnormalities in tumor cell populations. In addition, the relationships between tumor cell genomics and therapeutic outcomes are described. There are also supporting appendices on general bioscience, including the principles of histology (the cells and tissues of the body), genetics, pathology, radiology and pharmacology.
This book gives a thorough, detailed, yet concise account of the main bioscience, clinical and therapeutic aspects of tumors. It emphasizes the translational aspects of research into tumors with extensive discussions of interdisciplinary issues. The content in this book will be invaluable for researchers and clinicians involved in collaborative projects where it is necessary to understand fundamental issues in other branches of biomedicine.
This book gives a thorough, detailed, yet concise account of the main bioscience, clinical and therapeutic aspects of tumors. It emphasizes the translational aspects of research into tumors with extensive discussions of interdisciplinary issues. The content in this book will be invaluable for researchers and clinicians involved in collaborative projects where it is necessary to understand fundamental issues in other branches of biomedicine.
More details
Edition
2nd edition
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
Professional and scholarly
oncologists; cancer researchers; graduate students in oncology and related fields
Product notice
Paperback (trade)
Unsewn / adhesive bound
Dimensions
Height: 234 mm
Width: 188 mm
Thickness: 33 mm
Weight
1338 gr
ISBN-13
978-0-12-816920-9 (9780128169209)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
E-Book
11/2019
2nd Edition
Academic Press
€131.00
Available for download
Person
Dr. Leon Bignold teaches pathology to medical undergraduates and post graduates and has for the last 30 years. He also works as a diagnostic histopathologist in a hospital environment for the last 30 years. He has published 3 oncology books with Springer in the last 10 years. Leon Bignold is a regularly invited speaker at international oncology conferences.
Content
1. Introduction2. Theories and definitions of tumors3. Etio-pathogenesis of tumors4. Growth of cells, growth factors and oncogenes5. Hereditary Predispositions to Tumors, Tumor Suppressor Genes, and their Clinico-Genomic Complexities6. The tumor types: the complexities in the combinations and variabilities of their traits7. Epidemiology of Tumors8. Aspects of the prevention of tumors9. Clinical features of tumors 10. Morphologic assessment of cases of tumors11. Endoscopic Visualisation and Imaging in Diagnosis and Assessments of cases of Tumors12. Principles of surgery for tumors13. Principles of non-surgical therapies14. Aspects of radiation therapy15. Specific aspects of cytotoxic and hormonal drug therapies16. Immunological therapies17. Gene Therapies not Related to Immunological Therapies18. Other Therapies19. Care after primary treatment20. Costs, ethics and Malpractice Litigation
Appendix1. Principles of normal histology and related cell biology2. The normal genome3. Fixed Genomic Events and Possible Mechanisms of their Causation by Etiological Agents4. Genomic instabilities in Tumor Cells and the Immortality of Tumor Cell Populations5. Methods in Histologic and Molecular Assessments of Tumors6. Biomarkers in Epidemiology, Molecular Pathology and Oncology7. Sub-lethal injuries and deaths of cells and tissues8. Pretarget, Target and Recovery Defences of Cells Against Carcinogens and Cytotoxic Agents9. Developing New Therapies
Appendix1. Principles of normal histology and related cell biology2. The normal genome3. Fixed Genomic Events and Possible Mechanisms of their Causation by Etiological Agents4. Genomic instabilities in Tumor Cells and the Immortality of Tumor Cell Populations5. Methods in Histologic and Molecular Assessments of Tumors6. Biomarkers in Epidemiology, Molecular Pathology and Oncology7. Sub-lethal injuries and deaths of cells and tissues8. Pretarget, Target and Recovery Defences of Cells Against Carcinogens and Cytotoxic Agents9. Developing New Therapies