Clinical Trial Simulations using R

Trial simulations provide a very useful tool in planning and designing successful clinical trials. Because so many different variables go into the design, conduct, and outcome of a trial, using simulations to test different scenarios can help optimize trial parameters, including factors such as sample size, endpoint selection, observation timing, dosing regimen, along with many others. provide a This book will provide a simple trial simulation tool kit using the open source software R that the reader can immediately put to use.