Bioinformatics for Geneticists
1st Edition
Published on 21. February 2003
Book
Hardback
422 pages
978-0-470-84393-2 (ISBN)
Description
This timely book illustrates the value of bioinformatics, not simply as a set of tools but rather as a science increasingly essential to navigate and manage the host of information generated by genomics and the availability of completely sequenced genomes. Bioinformatics can be used at all stages of genetics research: to improve study design, to assist in candidate gene identification, to aid data interpretation and management and to shed light on the molecular pathology of disease-causing mutations. Written specifically for geneticists, this book explains the relevance of bioinformatics showing how it may be used to enhance genetic data mining and markedly improve genetic analysis.
Reviews / Votes
"...This book is essential reading for all those engaged in genetic research and should prove indispensable ..." (CAB Abstracts)More details
Series
Edition
1., Aufl.
Language
English
Place of publication
Chichester
United Kingdom
Publishing group
John Wiley and Sons Ltd
Target group
College/higher education
Professional and scholarly
Illustrations
Illustrations (some col.)
Dimensions
Height: 23.5 cm
Width: 15.9 cm
Weight
622 gr
ISBN-13
978-0-470-84393-2 (9780470843932)
Schweitzer Classification
Other editions
New editions
Michael R. Barnes
Bioinformatics for Geneticists
A Bioinformatics Primer for the Analysis of Genetic Data
Book
03/2007
2nd Edition
Wiley
€212.00
Shipment within 10-20 days
Content
List of Contributors; Foreword; SECTION I: AN INTRODUCTION TO BIOINFORMATICS FOR THE GENETICIST; Introduction: The Role of Genetic Bioinformatics (Michael R. Barnes and Ian C. Gray); Internet Resources for the Geneticist (Michael R. Barnes and Christopher Southan); Human Genetic Variation: Databases and Concepts (Michael R. Barnes); Finding, Delineating and Analysing Genes (Christopher Southan); SECTION II: THE IMPACT OF COMPLETE GENOME SEQUENCES ON GENETICS; Assembling a View of the Human Genome (Colin A. Semple); Mouse and Rat Genome Informatics (Judith A. Blake, Janan Eppig and Carol J. Bult); Genetic and Physical Map Resources - An Integrated View (Michael R. Barnes); SECTION III: BIOINFORMATICS FOR GENETIC STUDY DESIGN; From Linkage Peak to Culprit Gene: Following Up Linkage Analysis of Complex Phenotypes with Population-based Association Studies (Ian C. Gray); Genetic Studies from Genomic Sequence (Michael R. Barnes); SNP Discovery and PCR-based Assay Design: From In Silico Data to the Laboratory Experiment (Ellen Vieux, Gabor Marth and Pui Kwok); Tools for Statistical Analysis of Genetic Data (Aruna Bansal, Peter R. Boyd and Ralph McGinnis); SECTION IV: BIOLOGICAL SEQUENCE ANALYSIS AND CHARACTERIZATION; Predictive Functional Analysis of Polymorphisms: An Overview (Michael R. Barnes); Functional In Silico Analysis of Non-coding SNPs (Thomas Werner); Amino Acid Properties and Consequences of Substitutions (Matthew J. Betts and Robert B. Russell); SECTION V: GENETICS/GENOMICS INTERFACES; Gene Expression Informatics and Analysis (A. H. C. van Kampen, J. M. Ruijter, B. D. C. van Schaik, H. N. Caron and R. Versteeg); Proteomic Informatics (Jerome Wojcik and Alexandre Hamburger); Concluding Remarks: Final Thoughts and Future Trends (Michael R. Barnes and Ian C. Gray); Appendix I; Appendix II; Glossary; Index