
Control of Biofilm Infections by Signal Manipulation
Foreword by J.W. Costerton
Naomi Balaban(Editor)
Springer (Publisher)
Published on 17. December 2007
Book
Hardback
XVI, 175 pages
978-3-540-73852-7 (ISBN)
Description
In the well-watered groves of academe, most of us are content to gather worshipful students and technicians in a shady nook to contemplate the eternal verities and to plan extravagant feasts to celebrate our contributions to "knowledge" and to the gradual improvement of the human condition. As one convocation follows another, and as our funding agencies pump billions of dollars into incremental research that ?lls every possible pigeon-hole in which a gene makes a protein, a small number of intellectual athletes seize a pivotal concept and plunge into the real world. It is this small band of nimble and impossibly brave intellectual halfbackswho win gamesin the real world, and this book is the result of the drive and intellectual athleticism of its editor and several of her contributors. Bacteria affect humans more than any other life forms with which we share the blue planet, but our understandingof these invisible companionshas developed in a staggering pattern, crippled by our panic and consequent shifts of emphasis. When our race was threatened by epidemic diseases, we visualized bacteria as swarms of potentially lethal planktoniccells from which we must remain isolated by sanitation and which we had to kill by immunization and chemical antibacterial compounds. By the time this overriding threat had been obviated, we began to examine na- ral and pathogenic ecosystems by direct methods, and we were surprised to ?nd that planktonic bacteria are comparatively rare and that most prokaryotes grow in matrix-enclosedbio?lms.
More details
Series
Edition
2008 ed.
Language
English
Place of publication
Berlin
Germany
Publishing group
Springer Berlin
Target group
Professional and scholarly
Research
Illustrations
43 s/w Abbildungen, 13 farbige Abbildungen
XVI, 175 p. 56 illus., 13 illus. in color.
Dimensions
Height: 241 mm
Width: 160 mm
Thickness: 17 mm
Weight
494 gr
ISBN-13
978-3-540-73852-7 (9783540738527)
DOI
10.1007/978-3-540-73853-4
Schweitzer Classification
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Naomi Balaban
Control of Biofilm Infections by Signal Manipulation
Book
11/2010
Springer
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Naomi Balaban
Control of Biofilm Infections by Signal Manipulation
E-Book
11/2007
1st Edition
Springer
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Content
Bacterial Cell-to-cell Communication (Quorum Sensing).- Detection In Vitro of Quorum-Sensing Molecules and Their Inhibitors.- Quorum-Sensing Inhibitory Compounds.- Mathematical Modeling of Quorum-Sensing Control in Biofilms.- Animal Models Commonly Used to Study Quorum-Sensing Inhibitors.- In Vivo Studies: Inhibiting Biofilm-Associated Bacterial Infections Using QSIs.- Quorum Sensing in Streptococci.- Ironing Out the Biofilm Problem:The Role of Iron in Biofilm Formation.- Clinical Wound Healing Using Signal Inhibitors.