Advances and Recent Applications in LC-MS and HPLC
Book
Paperback/Softback
94 pages
978-0-12-804207-6 (ISBN)
Description
Advances and Recent Applications in LC-MS and HPLC presents the most recent developments in liquid chromatography and mass spectrometry techniques. The book's content reaches across a range of disciplines and cites several case studies to effectively capture the advanced applications that make LC-MS and HPLC multifunctional and exacting techniques. Liquid chromatography and mass spectrometry systems generate chromatograms of column peaks and can provide molecular weights of separated materials and their solvent complexes. However, while these systems can provide structural information to confirm the identity of the compounds separated, the process is very expensive. This book provides identification of simple compounds resulting from fragmentation studies and their subsequent results, offering the reader access to information unavailable elsewhere and allowing researchers to avoid incurring the costs associated with obtaining the hands-on results that LC-MS systems generate. Applicable to chemical analysis, bioanalysis, and medicinal chemistry, as well as pharmaceutical science, synthetic chemistry, and industrial chemistry, Advances and Recent Applications in LC-MS and HPLC is a multidisciplinary reference that arms scientists with the latest research. Detailed case studies enable researchers to make the book's concepts immediately implementable.
Advances and Recent Applications in LC-MS and HPLC presents the most recent developments in liquid chromatography and mass spectrometry techniques. The book's content reaches across a range of disciplines and cites several case studies to effectively capture the advanced applications that make LC-MS and HPLC multifunctional and exacting techniques. Liquid chromatography and mass spectrometry systems generate chromatograms of column peaks and can provide molecular weights of separated materials and their solvent complexes. However, while these systems can provide structural information to confirm the identity of the compounds separated, the process is very expensive. This book provides identification of simple compounds resulting from fragmentation studies and their subsequent results, offering the reader access to information unavailable elsewhere and allowing researchers to avoid incurring the costs associated with obtaining the hands-on results that LC-MS systems generate. Applicable to chemical analysis, bioanalysis, and medicinal chemistry, as well as pharmaceutical science, synthetic chemistry, and industrial chemistry, Advances and Recent Applications in LC-MS and HPLC is a multidisciplinary reference that arms scientists with the latest research. Detailed case studies enable researchers to make the book's concepts immediately implementable.
Advances and Recent Applications in LC-MS and HPLC presents the most recent developments in liquid chromatography and mass spectrometry techniques. The book's content reaches across a range of disciplines and cites several case studies to effectively capture the advanced applications that make LC-MS and HPLC multifunctional and exacting techniques. Liquid chromatography and mass spectrometry systems generate chromatograms of column peaks and can provide molecular weights of separated materials and their solvent complexes. However, while these systems can provide structural information to confirm the identity of the compounds separated, the process is very expensive. This book provides identification of simple compounds resulting from fragmentation studies and their subsequent results, offering the reader access to information unavailable elsewhere and allowing researchers to avoid incurring the costs associated with obtaining the hands-on results that LC-MS systems generate. Applicable to chemical analysis, bioanalysis, and medicinal chemistry, as well as pharmaceutical science, synthetic chemistry, and industrial chemistry, Advances and Recent Applications in LC-MS and HPLC is a multidisciplinary reference that arms scientists with the latest research. Detailed case studies enable researchers to make the book's concepts immediately implementable.
More details
Language
English
Place of publication
United States
Target group
Professional and scholarly
Dimensions
Height: 229 mm
Width: 152 mm
ISBN-13
978-0-12-804207-6 (9780128042076)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Persons
Dr. Quazi Syed Azharuddin is Assistant Professor in the Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India. He completed his post-graduate work and PhD in Chemistry from SGB Amravati University, Amravati, India. He has 5 years of research and teaching experience and he has authored or co-authored more than 30 papers. He has co-authored three books. His research interests include estimation of physico-chemical properties and intermolecular interactions of organic and inorganic molecules, stability constants of co-ordination compounds, chromatographic techniques, and spectral analysis. Dr. Devidas Totaram Mahajan is Head and Associate Professor in the Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India. He completed his post-graduate work in Chemistry from RTM Nagpur University, Nagpur, and his PhD from SGB Amravati University, Amravati. His research and teaching experience spans 34 years, and he's authored more than 50 papers. He has co-authored five books. Dr. Mahajan's research interests include the determination of physico-chemical properties and intermolecular interactions of synthetic and natural products, the characterization of commercial drugs, and drug designing. Dr. Vijay Hariram Masand is Assistant Professor in the Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India. He completed his post-graduate work and PhD in Chemistry from SGB Amravati University, Amravati, India. He has 7 years of research experience, 11 years of teaching experience, and more than 60 papers to his credit. He has co-authored three books. Dr. Masand's research interests include organic synthesis, heterocyclic chemistry, and computer-aided drug designing. Dr. Jayant M. Gajbhiye is a research scientist at National Chemical Laboratory, Pune, India. He completed his PhD and post-graduate work in chemistry from SGB Amravati University, Amravati, India. He has 13 years of research experience in the synthesis of active pharmaceutical intermediates and drug molecules, in collaboration with various industrially sponsored projects. He's published one patent and six papers. Dr. Nahed Nasser Eid El-Sayed is Assistant Professor in the Department of Chemistry at King Saud University, Riyadh, Saudi Arabia. He earned his MSc in Organic Chemistry from Ain Shams University, Cairo, Egypt, and his PhD in Synthetic Organic Chemistry from the School of Chemistry, Cardiff University, UK. Mr.Abdul Wajid is a Research Associate at SGB Amravati University, Amravati, India. He obtained his BPharm and MPharm degrees in Quality Assurances and completed his post-graduation studies at Government Pharmacy College, SGB Amravati University, Amravati. He has two years of research experience. Dr.Noor Mohammad is Assistant Professor in the Department of Chemistry, M.J. Fule Arts, Commerce & Science College, Bhatkuli, Amravati, India. He completed his post-graduation work and PhD in Chemistry from SGB Amravati University, Amravati. He has 8 years of teaching experience.
Dr. Quazi Syed Azharuddin is Assistant Professor in the Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India. He completed his post-graduate work and PhD in Chemistry from SGB Amravati University, Amravati, India. He has 5 years of research and teaching experience and he has authored or co-authored more than 30 papers. He has co-authored three books. His research interests include estimation of physico-chemical properties and intermolecular interactions of organic and inorganic molecules, stability constants of co-ordination compounds, chromatographic techniques, and spectral analysis. Dr. Devidas Totaram Mahajan is Head and Associate Professor in the Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India. He completed his post-graduate work in Chemistry from RTM Nagpur University, Nagpur, and his PhD from SGB Amravati University, Amravati. His research and teaching experience spans 34 years, and he's authored more than 50 papers. He has co-authored five books. Dr. Mahajan's research interests include the determination of physico-chemical properties and intermolecular interactions of synthetic and natural products, the characterization of commercial drugs, and drug designing. Dr. Vijay Hariram Masand is Assistant Professor in the Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India. He completed his post-graduate work and PhD in Chemistry from SGB Amravati University, Amravati, India. He has 7 years of research experience, 11 years of teaching experience, and more than 60 papers to his credit. He has co-authored three books. Dr. Masand's research interests include organic synthesis, heterocyclic chemistry, and computer-aided drug designing. Dr. Jayant M. Gajbhiye is a research scientist at National Chemical Laboratory, Pune, India. He completed his PhD and post-graduate work in chemistry from SGB Amravati University, Amravati, India. He has 13 years of research experience in the synthesis of active pharmaceutical intermediates and drug molecules, in collaboration with various industrially sponsored projects. He's published one patent and six papers. Dr. Nahed Nasser Eid El-Sayed is Assistant Professor in the Department of Chemistry at King Saud University, Riyadh, Saudi Arabia. He earned his MSc in Organic Chemistry from Ain Shams University, Cairo, Egypt, and his PhD in Synthetic Organic Chemistry from the School of Chemistry, Cardiff University, UK. Mr.Abdul Wajid is a Research Associate at SGB Amravati University, Amravati, India. He obtained his BPharm and MPharm degrees in Quality Assurances and completed his post-graduation studies at Government Pharmacy College, SGB Amravati University, Amravati. He has two years of research experience. Dr.Noor Mohammad is Assistant Professor in the Department of Chemistry, M.J. Fule Arts, Commerce & Science College, Bhatkuli, Amravati, India. He completed his post-graduation work and PhD in Chemistry from SGB Amravati University, Amravati. He has 8 years of teaching experience.
Dr. Quazi Syed Azharuddin is Assistant Professor in the Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India. He completed his post-graduate work and PhD in Chemistry from SGB Amravati University, Amravati, India. He has 5 years of research and teaching experience and he has authored or co-authored more than 30 papers. He has co-authored three books. His research interests include estimation of physico-chemical properties and intermolecular interactions of organic and inorganic molecules, stability constants of co-ordination compounds, chromatographic techniques, and spectral analysis. Dr. Devidas Totaram Mahajan is Head and Associate Professor in the Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India. He completed his post-graduate work in Chemistry from RTM Nagpur University, Nagpur, and his PhD from SGB Amravati University, Amravati. His research and teaching experience spans 34 years, and he's authored more than 50 papers. He has co-authored five books. Dr. Mahajan's research interests include the determination of physico-chemical properties and intermolecular interactions of synthetic and natural products, the characterization of commercial drugs, and drug designing. Dr. Vijay Hariram Masand is Assistant Professor in the Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India. He completed his post-graduate work and PhD in Chemistry from SGB Amravati University, Amravati, India. He has 7 years of research experience, 11 years of teaching experience, and more than 60 papers to his credit. He has co-authored three books. Dr. Masand's research interests include organic synthesis, heterocyclic chemistry, and computer-aided drug designing. Dr. Jayant M. Gajbhiye is a research scientist at National Chemical Laboratory, Pune, India. He completed his PhD and post-graduate work in chemistry from SGB Amravati University, Amravati, India. He has 13 years of research experience in the synthesis of active pharmaceutical intermediates and drug molecules, in collaboration with various industrially sponsored projects. He's published one patent and six papers. Dr. Nahed Nasser Eid El-Sayed is Assistant Professor in the Department of Chemistry at King Saud University, Riyadh, Saudi Arabia. He earned his MSc in Organic Chemistry from Ain Shams University, Cairo, Egypt, and his PhD in Synthetic Organic Chemistry from the School of Chemistry, Cardiff University, UK. Mr.Abdul Wajid is a Research Associate at SGB Amravati University, Amravati, India. He obtained his BPharm and MPharm degrees in Quality Assurances and completed his post-graduation studies at Government Pharmacy College, SGB Amravati University, Amravati. He has two years of research experience. Dr.Noor Mohammad is Assistant Professor in the Department of Chemistry, M.J. Fule Arts, Commerce & Science College, Bhatkuli, Amravati, India. He completed his post-graduation work and PhD in Chemistry from SGB Amravati University, Amravati. He has 8 years of teaching experience.
Author
Assistant Professor, Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India
Head and Associate Professor, Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India
Department of Chemistry, Vidya Bharati Mahavidyalaya College, Amravati, India
College of Pharmacy, Salman Bin Abdulaziz University, Saudi Arabia
Organic Chemistry Division, CSIR-National Chemical Laboratory, Maharashtra, India
Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia
SGB Amravati University, Amravati, Maharashtra, India
Department of Chemistry, M.J.Fule Arts, Commerce & Science College, Bhatkuli, Amravati, India
Content
TABLE OF CONTENTS 1. High Performance Liquid Chromatography 2. HPLC Column/Separation Modes 3. HPLC and Column Maintenance 4. Sample Preparation and Separations Development 5. LC/MS Interfaces 6. LC/MS Overview 7. Mass Analyzers 8. Mass Spectrometer Maintenance 9. Application Areas for LC/MS 10. Trace Analysis and LC/MS/MS 11. Drug Discovery and Benchtop LC/MS 12. Proteomics: LC/MALDI/TOF and MS/MS Libraries 13. The Future of LC/MS