Stereoselective Synthesis
Published on 28. July 1995
Book
Hardback
542 pages
978-0-471-95250-3 (ISBN)
Description
Introduces a new, simplified classification for stereoselective reactions based on changes in the number of chiral centres taking place, emphasizing the three-dimensional representations of transition states in which stereoselectivity is determined. Using stereochemical vocabulary in accordance with IUPAC rules, it covers analysis of factors in which asymmetric induction occurs, the interplay between steric and electronic effects, the importance of conformational control, advantages of intramolecularity and the majority of important reaction types used in modern stereoselective synthesis.
More details
Language
English
Place of publication
Chichester
United Kingdom
Publishing group
John Wiley and Sons Ltd
Target group
College/higher education
Professional and scholarly
Illustrations
Illustrations
Dimensions
Height: 235 mm
Width: 156 mm
Weight
970 gr
ISBN-13
978-0-471-95250-3 (9780471952503)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Content
Partial table of contents: Type 0 Reactions: Reactions in Which No New Chiral Centres Are Created. Type I Reactions: Those Proceeding with Either Inversion or with Retention of Configuration at a Single Chiral Centre. Simple Chirality Transfer Reactions: Those in Which a Single Chiral Centre Is Transferred with Concomitant Migration of One or More Double Bonds. Type II Reactions: Simple Diastereoselectivity in 1,2-Additions to Alkenes, Diels-Alder and 1,3-Dipolar Cycloadditions and the ene Reaction. Type II Reactions: Occasional Diastereoselectivity. Type III Reactions: Those Involving Asymmetric Induction. Type III Reactions of Diastereotopic and Enantiotopic Atoms and Groups; Enzyme Catalysed Reactions. Index.