Expmtl Toxicology The Basic Issues
The Basic Issues
2nd Edition
Published on 27. January 1994
Book
Hardback
566 pages
978-0-85186-451-8 (ISBN)
Description
This volume addresses the basic issues concerned with the practice of experimental toxicology and discusses such issues as experimental design, biochemical issues, animal husbandry, species differentiation, carcinogenesis and laboratory design. It has been revised and updated to give special attention to recent advances in the areas of molecular, genetic and reproductive toxicology and in the knowledge regarding the multiplicity of enzymes involved in foreign compound metabolism.
More details
Edition
2nd New edition
Language
English
Place of publication
Cambridge
United Kingdom
Target group
College/higher education
Professional and scholarly
Edition type
New edition
Product notice
Unsewn / adhesive bound
Dimensions
Height: 234 mm
Width: 156 mm
ISBN-13
978-0-85186-451-8 (9780851864518)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
E-Book
10/2007
2nd Edition
Royal Society of Chemistry
€40.99
Available for download
Previous edition
Book
12/1990
Royal Society of Chemistry
€44.15
Article exhausted; check for reprint
Persons
Author
University of Bradford, UK
Inveresk Research International
International Agency for Research on Cancer
University of Surrey
Peptide Therapeutics Group PLC
Bibra Toxicology International
Fisons Plc.
WRC plc
Copeland Associates
P N Lee Statistics and Computing Ltd
University of Birmingham
Imperial College London
40 years research into the biology and pathology of the skin and its response to injury. Research into the nutrition and physiology of trace and xenbiotic metals in the skin. Study of intrinsic cytoprotective mechanisms against metal toxicity. Special studies onthe biological value of silver in wound care and as an antimicrobial agent in medical devices. International consultant and lecturer. Published 250 scientific papers and book chapters.
40 years research into the biology and pathology of the skin and its response to injury. Research into the nutrition and physiology of trace and xenbiotic metals in the skin. Study of intrinsic cytoprotective mechanisms against metal toxicity. Special studies onthe biological value of silver in wound care and as an antimicrobial agent in medical devices. International consultant and lecturer. Published 250 scientific papers and book chapters.
Content
Effects of physical form, route and species, A. Wilson; influence of animal species, strain, age, hormonal and nutritional status, F. Roe; experimental design, A. Wilson; the biochemical principles of toxicology, W. Aldridge; animal husbandry, A. Lansdown; inhalation toxicology, R. Riley and D. Conning; histopathology in safety evaluation, J. Evans and W. Butler; the metabolism and disposition of xenobiotics, S. Gangoli and J. Phillips; theory and practice in metabolic studies, J. Phillips and S. Gangoli; immunotoxicology - conceptual problems, H. Amos; perspectives - the evaluation of reproductive toxicity and teratogenicity, A. Lansdown; genetic toxicology, D. Anderson; molecular toxicology, P. Rumsby; testing for carcinogenicity, P. Grasso; in vitro methods for teratology testing, D. Anderson; assessing chemical injury in the reproductive system, S. Gangoli and J. Phillips; statistics, P. Lee; risk assessment of chemicals, D. Lovell; epidemiology, G. Paddle; information and consultancy services in toxicology, D. Conning; regulations and advisory requirements in relation to food, D. Conning; the influence of a growing environmental awareness on toxicology laboratory design, D. Anderson and B. Copeland; good laboratory practice, R. Hawkins; ethics in experiments on animals, D. McGregor.