Spongiform Encephalopathies
Published in February 1994
Book
Hardback
320 pages
978-0-443-04928-6 (ISBN)
Description
Published four times a year, the "British Medical Bulletin" provides up-to-date reviews on areas of current development and research. This volume focuses on spongiform encephalopathy, and should interest neurologists, psychiatrists, pathologists and researchers in veterinary medicine and biology.
More details
Series
Language
English
Place of publication
London
United Kingdom
Publishing group
Elsevier Health Sciences
Target group
College/higher education
Professional and scholarly
Illustrations
line drawings, half-tones, index
Dimensions
Height: 216 mm
Width: 140 mm
Weight
521 gr
ISBN-13
978-0-443-04928-6 (9780443049286)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Content
Overview of the transmissible spongiform encephalopathies - prion protein disorders; neuropathology of spongiform encephalopathies in humans; scrapie pathogenesis; the diversity in the neuropathology of scrapie-like diseases in animals; inactivation of spongiform encephalopathy agents; scrapie strain variation and mutation; the PrP gene and its association with spongiform encephalopathies; scrapie associated PrP accumulation and its prevention - insights from cell culture; transgenics and cell biology of prion diseases - investigations of PrPSc synthesis and diversity; genetic control of nucleation and polymerization of host precursors to infectious amyloids in the transmissible amyloids of brain; molecular genetics of Gerstmann-Straussler-Scheinker syndrome; BSE epidemiology and control; epidemiology of Creutzfeldt-Jakob disease; developments in diagnosis; fatal familial insomnia and the widening spectrum of prion diseases; replication models (mice) and the future.