Systems Biology
Definitions and Perspectives
Published on 4. October 2007
Book
Paperback/Softback
XVII, 408 pages
978-3-540-74269-2 (ISBN)
Description
For life to be understood and disease to become manageable, the wealth of postgenomic data now needs to be made dynamic. This development requires systems biology, integrating computational models for cells and organisms in health and disease; quantitative experiments (high-throughput, genome-wide, living cell, in silico); and new concepts and principles concerning interactions. This book defines the new field of systems biology and discusses the most efficient experimental and computational strategies. The benefits for industry, such as the new network-based drug-target design validation, and testing, are also presented.
More details
Series
Edition
1st ed. 2005. 2nd printing 2007
Language
English
Place of publication
Berlin
Germany
Publishing group
Springer Berlin
Target group
College/higher education
Research
Illustrations
XVII, 408 p.
Dimensions
Height: 235 mm
Width: 155 mm
Thickness: 24 mm
Weight
645 gr
ISBN-13
978-3-540-74269-2 (9783540742692)
DOI
10.1007/b95175
Schweitzer Classification
Other editions
Additional editions
Book
09/2005
Springer
€213.99
Shipment within 10-15 days
E-Book
01/2005
Springer
€213.99
Available for download
Content
Systems Biology of Apoptosis.- Mathematical Modeling of the Wnt-Pathway.- Modeling Signaling Pathways - A Yeast Approach.- Mechanistic and Modular Approaches to Modeling and Inference of Cellular Regulatory Networks.- Scientific and Technical Challenges for Systems Biology.- Integration of Metabolic and Signaling Networks.- From Isolation to Integration, a Systems Biology Approach for Building the Silicon Cell.- What's Systems Biology: From Genes to Function and Back.- Systems Biology: Recent Developments and New Trends.- A Modular Systems Biology Analysis of the Cell Cycle Entrance into S Phase.- Metabolic Control Analysis.- Mesoscopic Kinetics and its Applications in Protein Synthesis.- E. coli Glycolysis.- Kinetic Modeling of the E. coli Metabolism.- No Music without Melody: How to Understand Biochemical Systems by Understanding Their Dynamics.- Systems Biology of the Yeast Cell Cycle Engine.- Quantification of in vivo Molecular Fluxes: A Key Methodology for Metabolic Systems Biology.-Modeling the E. coli cell: The Need for Computing, Cooperation, and Consortia.