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Powyshenie rastworimosti s pomosch'ü tehniki likizolida
Published on 13. April 2024
Book
Paperback/Softback
68 pages
978-620-7-38133-3 (ISBN)
Description
Poskol'ku likisolidnye tabletki soderzhat lekarstwo, rastworennoe w propilenglikole, powerhnost' preparata, dostupnaq dlq rastworeniq, sil'no uwelichiwaetsq. Koroche goworq, lekarstwo prisutstwuet w forme molekulqrnoj dispersii, posle togo kak ono raspadaetsq w srede rastworeniq. Sledowatel'no, molekulqrno dispergirowannoe lekarstwo w likizolidnyh tabletkah mozhet byt' prichinoj bol'shej skorosti rastworeniq po srawneniü s suschestwuüschej na rynke formuloj. Jeto takzhe otrazitsq na uwelichenii peroral'noj biodostupnosti. Takzhe ranee bylo dokazano, chto pri nizkoj koncentracii preparata w zhidkom lekarstwennom sredstwe proishodit bolee bystroe wyswobozhdenie preparata. Jeto swqzano s tem, chto lekarstwo w wysokoj koncentracii imeet tendenciü osazhdat'sq w porah kremnezema (Aerosil 200). Profil' rastworeniq likisolidnyh tabletok podtwerzhdaet wysheukazannuü gipotezu.
More details
Language
Other
Product notice
Paperback (trade)
Unsewn / adhesive bound
Dimensions
Height: 220 mm
Width: 150 mm
Thickness: 5 mm
Weight
119 gr
ISBN-13
978-620-7-38133-3 (9786207381333)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Persons
Dr. Vinod Kumar Dhote und Dr. Kanika Dhote waren an der Erforschung und Entwicklung neuartiger Arzneimittelverabreichungssysteme und der Arzneimittelforschung beteiligt.