This book presents the principle, strengths and weaknesses, and progress of various vaccine technologies against COVID-19. Additionally, important terms such as clinical phases, efficacy and sterilizing immunity are explained. In this second edition, the already approved vaccines are also presented and the importance of viral variants is explained
Patric U. B. Vogel is a biologist with many years of experience with various biopharmaceuticals, from live vaccines to DNA vaccines. He was a registered Qualified Person for several years and has regularly released coronavirus vaccines against animal diseases, among other things. Since 2019, he has been an author, trainer and consultant in the pharmaceutical field.
Introduction.- Coronaviruses: history and viral properties.- Vaccine technologies, approaches against COVID-19, clinical phases.- Attenuated live vaccines.- Vector vaccines and virus-like particles.- Inactivated vaccines.- Recombinant proteins (protein subunits).- Nucleic acid-based vaccines.- Other aspects - One vaccine for all? - Herd immunity - Duration of immunity - Sterilizing immunity.- Summary.