The lack of adherence to medication is a growing public health problem worldwide and is costing many patients their good health and healthcare systems billions of dollars. Analytical Chemistry for Assessing Medication Adherence introduces the concept of medication adherence/compliance and reports international perspectives on medication adherence while highlighting its importance. It then describes the opportunities for analytical chemistry to assess medication adherence and thereby provide an evidence base for clinicians to improve patient health outcomes. The authors highlight the strengths and weaknesses of each of the analytical techniques cited in addition to categorizing the findings in terms of the biological samples used to assess adherence and identifying methods to extract biological samples prior to analysis. The final chapter provides the authors' perspective in this area, emphasising the importance of medication optimization for individual patients.
- Surveys the strengths, weaknesses, and appropriateness of existing instruments and techniques and points the way toward a program of therapeutic optimization
- Brings together data scattered amongst professional journals and other sources in a single convenient volume
- Presents the problem of adherence and the authors' evaluation of possible solutions based on the analysis of patient bio-samples
Sangeeta Tanna has a PhD in Pharmaceutics and is a Reader in Pharmaceutical Bioanalysis. Her expertise and research interests are the pharmaceutical bioanalysis and drug delivery fields. Her early research focused on developing instrumental methods for measuring the glucose-dependent delivery of insulin from a 'smart" gel. This led to the development of microanalytical methodologies for the determination of therapeutic drugs from dried blood spots based on LC-MS, LC-MS/MS, and LC-HRMS studies. Applications of this work to patient healthcare include improved medications for newborn babies and to assess adherence to cardiovascular drug therapy for adult patients. She has a track record of published papers, invited international conference presentations, grants, and awards for this research.