Pouchitis and Ileal Pouch Disorders

A Multidisciplinary Approach for Diagnosis and Management
 
 
Elsevier (Verlag)
  • 1. Auflage
  • |
  • erschienen am 5. November 2018
  • |
  • 570 Seiten
 
E-Book | PDF mit Adobe DRM | Systemvoraussetzungen
978-0-12-809629-1 (ISBN)
 

Pouchitis and Ileal Pouch Disorders: A Multidisciplinary Approach for Diagnosis and Management provides much needed information on the evolution of pouch surgery, pouch surgery techniques, and surgery-associated complications, including inflammatory, functional, neoplastic, and metabolic complications. The book provides information on the anatomy of the pouch, pathogenesis of pouchitis and other pouch disorders, proper diagnostic modalities, and medical, endoscopic and surgical options for those disorders. The information has been compiled from a panel of national and international leading experts in the field, including basic scientists, gastrointestinal (GI) pathologists, GI radiologists, gastroenterologists, and more.

  • Features never-before-published information and technology from the vast experience of the contributors and editors in diagnosis and medical, endoscopic, and surgical management of pouchitis and other pouch disorders
  • Contains easy to access recommendations from experts
  • Provides access to an accompanying website with videos of endoscopic demonstrations of various configurations of the pouch, endoscopic evaluation of pouch disorders, and endoscopic treatment of pouch strictures, fistula, and anastomotic leaks/sinuses
  • Englisch
  • Saint Louis
  • |
  • USA
  • 318,88 MB
978-0-12-809629-1 (9780128096291)
weitere Ausgaben werden ermittelt
  • Front Cover
  • Pouchitis and Ileal Pouch Disorders: A Multidisciplinary Approach for Diagnosis and Management
  • Copyright
  • Dedication
  • Contents
  • Contributors
  • Author's Biography
  • Preface
  • Chapter 1 Current Medical Therapies for Ulcerative Colitis
  • Introduction
  • Assessing Disease Severity and Response to Medical Therapy
  • Aminosalicylates
  • Oral Preparations
  • Rectal Preparations
  • Efficacy of ASA
  • Corticosteroids
  • Systemic Steroids
  • Targeted Steroids
  • Maintenance Therapy and Adverse Effects
  • Antimetabolites
  • Thiopurines
  • Combination Therapy
  • Methotrexate
  • Calcineurin Inhibitors
  • Intravenous CSA
  • Other Formulations of CSA
  • Tacrolimus
  • Mammalian Target of Rapamycin Inhibitors
  • Mycophenolate Motefil
  • Monoclonal Antibodies to TNF- a
  • Infliximab
  • Other TNF Inhibitors
  • Anti-integrins
  • Vedolizumab
  • Natalizumab
  • Etrolizumab
  • Smoking, Nicotine, and UC
  • Induction Therapy
  • Maintenance Therapy
  • Altering the Microbiome in UC
  • Probiotics
  • Antibiotics
  • Fecal Microbiota Transplantation
  • Novel/Experimental Agents
  • MAdCAM Inhibitors
  • Janus Kinase Inhibitors
  • ICAM-1 Inhibitors
  • Summary and Recommendations
  • References
  • Further Reading
  • Chapter 2 Indications and Preoperative Medical Management of Ulcerative Colitis Patients Undergoing Pouch Surgery
  • Introduction
  • Indications for the Ileal Pouch
  • Medically Refractory UC
  • UC Patients With Medicine-Associated Side Effects
  • Colitis-Associated Neoplasia
  • Crohn's Colitis
  • Indeterminate Colitis
  • Familial Adenomatous Polyposis
  • Other Indications
  • Periopertive Use of Anticoagulation
  • Periopertive Use of Mesalamines
  • Periopertive Use of Corticorticosteroids
  • Periopertive Use of Immunomodulators
  • Purine Analogs
  • Methotrexate
  • Cyclosporine A
  • Periopertive Use of Antitumor Necrosis Factor Agents
  • Periopertive Use of Anti-integrin Agents
  • Perioperative Nutrition Support
  • Perioperative Blood Transfusion
  • Summary and Recommendations
  • References
  • Chapter 3 Preoperative Evaluation and Techniques of Colectomy and Ileal Pouch Surgery
  • Introduction
  • Preoperative Evaluation
  • Establishing Patient Goals
  • Determining Candidacy for IPAA
  • Thromboembolic Issues
  • Enterostomal Preparation
  • Role of the Multidisciplinary IPAA Specialty Team
  • Shared Patient Experiences
  • Operative Technique of Restorative Proctocolectomy
  • Deciding Among Pouch Configurations
  • Stapled vs Hand-Sewn (Mucosectomy) Anastomosis
  • Alternatives to IPAA
  • Summary and Recommendations
  • References
  • Chapter 4 Risk Factors for Short- and Long-Term Complications of Ileal Pouch Surgery
  • Introduction
  • Risk Factors for Short-Term (30 Days) Complications
  • Anastomotic Leak
  • Pelvic Abscess and Sepsis
  • Wound Infection
  • Risk Factors for Long-Term Surgical Complications
  • Pouch-Related Fistula
  • Small Bowel Obstruction
  • Afferent Limb Syndrome
  • Efferent Limb Syndrome
  • Non-CD Strictures
  • The Leak at the Tip of the "J"
  • Pouch Prolapse
  • Pouch Sinus
  • Risk Factors for Pouch Failure
  • Patient Factors
  • Disease Factors
  • Surgical Technique Factors
  • Preoperative Factors
  • Postoperative Factors
  • Summary and Recommendations
  • References
  • Chapter 5 Stoma, Mucous Fistula, Diverted Large Bowel, and Ileo-Rectal Anastomosis
  • Introduction
  • End Ileostomy
  • Loop Ileostomy
  • Complications of Ileostomy and Disease of the Neo-Small Bowel
  • Post-colectomy Enteritis
  • Stoma Complications
  • Peristomal Cutaneous Lesions
  • Occurrence of CD of NSI in Patients With Primary or Secondary Stoma After Colectomy
  • Mucous Fistula
  • Diverted Rectum or Hartmann Pouch
  • IRA for UC
  • Summary and Recommendations
  • Acknowledgment
  • Disclosure
  • References
  • Chapter 6 The Ileal Pouch for Familial Adenomatous Polyposis
  • Introduction
  • Indications for Surgery
  • Timing of Surgery
  • Surgical Options and Extent of Resection
  • Colectomy and IRA
  • TPC and IPAA
  • Anal Mucosectomy and Hand-Sewn Anastomosis Versus Double-Stapled IPAA
  • Surgical Morbidity and Functional Outcomes
  • Surgical Morbidity
  • Postoperative Functional Expectations
  • QOL After IPAA
  • Pouchitis in FAP
  • Pouch Strictures
  • Postoperative Surveillance After IPAA
  • Chemoprevention in FAP
  • Special Circumstances: Desmoid Disease and IPAA in FAP
  • Summary and Recommendations
  • References
  • Chapter 7 Ileal Pouch in Children
  • Introduction
  • Indication for Colectomy in Children
  • Technical Aspects of Restorative Proctocolectomy in Children
  • Staged Construction of Ileal Pouch
  • J- vs S- Pouch
  • Mucosectomy vs Without Mucosectomy
  • Hand Sewn vs Stapled Anastomoses
  • The Pull-Through Techniques
  • Comparison of Straight Pull-Through vs J-Pouch Ileoanal Anastomosis
  • Open vs Laparoscopic Surgery
  • Ileal Pouch for FAP
  • Ileal Rectal Anastomosis
  • Functional Outcomes of Ileal Pouch in Children
  • Risk Factors for Adverse Outcomes of the Pouch
  • Risk of Neoplasia of the Pouch
  • General Health Maintenance of Pediatric Patients With Pouches
  • Summary and Recommendations
  • References
  • Chapter 8 The Cleveland Classification of Ileal Pouch Disorders
  • Introduction
  • Surgical and Mechanical Disorders
  • Anastomotic or Suture Line Leaks
  • Pelvic Sepsis and Pouch Abscess
  • Pouch Sinus
  • Pouch Fistulae
  • Strictures
  • Afferent Limb Syndrome
  • Efferent Limb Syndrome
  • Pouch Prolapse
  • Folded Pouch and Twisted Pouch
  • Floppy Pouch Complex
  • Infertility
  • Sexual Dysfunction
  • Portal and Mesenteric Vein Thrombi
  • Other Surgery-Related Disorders of the Pouch
  • Inflammatory Disorders
  • Pouchitis
  • Cuffitis
  • CD of the Pouch
  • Small Intestinal Bacterial Overgrowth
  • Inflammatory Polyps
  • Functional Disorders of the Ileal Pouch
  • Irritable Pouch Syndrome
  • Dyssynergic Defecation
  • Dysplasia and Neoplasia
  • Metabolic and Systemic Complications
  • Anemia
  • Bone Loss
  • Abnormal Vitamin B12
  • Abnormal Bile Acid Metabolism
  • Nephrolithiasis
  • Celiac Disease
  • Summary and Recommendations
  • References
  • Chapter 9 Genetic Factors in the Pathogenesis of Inflammatory Pouch Disorders
  • Indtroduction
  • Experimental Considerations in Pouch Genetic Analyses
  • Genetic Associations With Pouch Inflammatory Complications
  • Acute Pouchitis
  • Chronic Pouchitis and CDL Phenotype
  • Alterations in Gene Expression in Pouch Inflammation
  • Outcome Prognostication and Risk Management
  • Summary and Recommendations
  • References
  • Chapter 10 Microbiota in Pouchitis and De Novo Crohn's Disease of the Ileal Pouch
  • Introduction
  • Primary "Idiopathic" Pouchitis
  • Nonmicrobial Factors Linked to the Development of Idiopathic Pouchitis
  • The Gut Microbiota
  • Characterization of the Composition of the Gut Microbiota
  • Microbial Ecological Diversity
  • 16S rRNA Sequencing and Microbial Ecology
  • The Application of High-Throughput and Data-Driven Approaches to Microbial Ecology (i.e., "Omics")
  • Combining "Omics" in Systems Biology
  • Microbial Taxonomy and Intestinal Disease
  • Dysbiosis of the Gut Microbiome, Idiopathic Pouchitis, and a Word of Caution
  • Microbial Ecological Changes Follow Stoma Reversal and Restoration of Flow of Enteric Content Into the Ileal Pouch
  • Bacterial Diversity Is Altered in the Ileal Pouch
  • Cellular Changes Follow Stoma Reversal and Restoration of Flow of Enteric Content Into the Ileal Pouch
  • Sulphate Reducing Bacteria and Ideopathic Pouchitis
  • Resolution of Idiopathic Pouchitis With Antibiotic Treatment
  • Crohn's Disease of the Ileal Pouch
  • Diagnosis of Crohn's Disease of the Ileal Pouch
  • Etiology and Pathobiological Forms of Crohn's Disease of the Ileal Pouch
  • Treatment
  • Future Directions in Relation to Idiopathic Pouchitis and Crohn's Disease of the Ileal Pouch
  • Summary and Recommendations
  • References
  • Chapter 11 Pathogenesis of Pouchitis
  • Introduction
  • Genetical Factors
  • Role of Microbiota
  • Environmental and Dietary Factors
  • Smoking
  • Pollution
  • Medications
  • Dietary Factors
  • Pelvic Radiation
  • Immunological Factors
  • Response to Antiinflammatory Biological Agents
  • Pouchitis and Extraintestinal Manifestations (EIM)
  • Pouchitis and Other Immune-Mediated Disorders
  • Immunogenetics and Immunoserology
  • Innate Immunity
  • Humoral Immunity
  • Adaptive Immunity
  • Inflammatory Mediators
  • Tissue Ischemia and Hypoxia
  • Pouchitis and Surgical Techniques
  • Evidence of Tissue Ischemia and Hypoxia From Clinical Therapy
  • Thromocytosis and Portal Vein Thrombosis
  • Mesentry and Metabolic Factors
  • Summary and Recommendations
  • References
  • Chapter 12 Risk Factors for Chronic Inflammatory Disorders of Ileal Pouch
  • Introduction
  • Risk Factors for Chronic Pouchitis
  • Genetic Factors
  • Interleukin-1 Receptor Antagonist Allele 2
  • NOD2/CARD15
  • Toll-Like Receptors
  • TNF Allele 2
  • Primary Sclerosing Cholangitis
  • Other EIMs
  • Extensive Colitis and Backwash Ileitis
  • Male Gender
  • Young Age at UC Diagnosis or Surgery
  • Nonsmoking Status
  • Autoimmune Disorders
  • Preoperative Use of Corticosteroids
  • Preoperative Thrombocytosis
  • Type of Ileal Pouch
  • Postoperative Use of NSAIDs
  • Serological Abnormalities
  • Risk Factors for CD of the Pouch
  • Family History of CD
  • Preoperative Diagnosis of IC
  • Smoking
  • Young Age at Diagnosis or Long Duration of Having an Ileal Pouch
  • Ethnicity
  • The Absence of PSC
  • Serological Abnormalities
  • ASCA
  • Anti-CBir1
  • Risk Factors for Cuffitis
  • Summary and Recommendations
  • Disclosure
  • References
  • Chapter 13 Adverse Metabolic Conditions after Pouch Surgery
  • Introduction
  • Anemia and Iron Deficiency
  • Vitamin B12 Deficiency
  • Bile Acid Malabsorption
  • Vitamin D Deficiency
  • Bone Loss and Bone Fracture
  • Nephrolithiasis
  • Fat Metabolism
  • Summary and Recommendation
  • References
  • Chapter 14 Diagnosis of Ileal Pouch Disorders: Clinical Evaluation
  • Introduction
  • Pouchitis
  • Crohn's Disease of the Pouch
  • Cuffitis
  • Irritable Pouch Syndrome
  • Postsurgical Anatomic Problems
  • Stenosis
  • Afferent Limb Syndrome
  • Efferent Limb Syndrome
  • Pouch Prolapse
  • Acute and Chronic Pouch Leaks
  • Infections of the Pouch
  • Summary and Recommendation s
  • References
  • Chapter 15 Diagnosis of Pouch Disorders: Endoscopy
  • Introduction
  • Anatomy and Landmarks of the Ileal Pouch
  • J-Pouch
  • S-Pouch
  • Kock Pouch
  • Barnett Continent Intestinal Reservoir
  • Ileostomy
  • Diverted Pouch
  • Preparation and Precaution for Pouch Endoscopy
  • Pouchoscopy in Diagnosis and Differential Diagnosis
  • Pouchitis
  • CD of the Pouch
  • Cuffitis
  • Structural Disorders of the Pouch
  • Functional Disorders of the Pouch
  • Endoscopy in Surveillance of Pouch Neoplasia
  • EGD and Capsule Endoscopy
  • Other Endoscopy Modalities
  • Ileoscopy via Stoma
  • Small Bowel Endoscopy
  • Optical Coherence Tomography
  • Endoscopy Ultrasonography
  • Intraoperative Endoscopy
  • Summary and Recommendations
  • References
  • Chapter 16 Diagnosis of Pouch Disorders: Histology
  • Introduction
  • Pouchitis
  • Secondary Pouchitis With Identifiable Infectious Agents
  • Other Secondary Pouchitis
  • Pouch Prolapse
  • Irritable Pouch Syndrome
  • Crohn Disease of the Ileal Pouch
  • Pouch Neoplasia
  • Cuffitis and Prepouch Ileitis
  • Histologic Examination of Excised Pouch Specimen
  • Summary and Recommendations
  • References
  • Further Reading
  • Chapter 17 Disease Activity Instruments for Pouchitis and Other Inflammatory Disorders of the Pouch
  • Introduction
  • Disease Activity Indices for Pouchitis
  • St. Mark's Index
  • Pouchitis Disease Activity Index
  • Modified Pouchitis Disease Activity Index
  • The Heidelberg Pouchitis Activity Score
  • Disease Activity Indices for CD and Cuffitis
  • The Use of PDAI in CD of the Pouch
  • Cuffitis Disease Activity
  • Summary and Recommendations
  • Disclosures
  • References
  • Chapter 18 Diagnosis and Management of Ileal Pouch Disorders: Role of Abdominal and Pelvic Imaging
  • Introduction
  • Techniques of Common Imaging Modalities
  • Water-Soluble Contrast Enema
  • Defecography
  • Computed Tomography and Enterography
  • Magnetic Resonance Imaging, Defecography, and Enterography
  • Small Bowel Series
  • Utility of Imaging in Common Ileal Pouch Disorders
  • Delineation of Integrity of Pouch Before Stoma Closure
  • Postoperative Morphological Changes
  • Pouchitis
  • Crohn Disease of the Pouch
  • Pouch Stricture
  • Pouch Fistula
  • Anastomotic and Suture/Staple Line Leaks
  • Floppy Pouch Complex
  • Efferent Limb Syndrome
  • Pouch Dysmotility and Inertia
  • Other Abnormalities
  • A Combined Approach for the Evaluation of Pouch Disorders
  • Interventional Radiology in Ileal Pouch Disorders
  • Abscess Aspiration and Drainage
  • CT-Guided Wire Placement
  • Salvage Interventional Radiology Procedure
  • Summary and Recommendations
  • References
  • Chapter 19 Diagnosis of Pouch Disorders: Laboratory Tests
  • Introduction
  • Laboratory Tests for the Assessment of Risk Factors and Implication in Pathogenesis
  • Immunogenotypic Markers
  • Precolectomy Blood Platelet Count
  • Preoperative Serum Albumin
  • Fecal Butyrate and Bile Acids
  • Laboratory Tests for the Assessment of Disease Activity and Diagnosis
  • Erythrocyte Sedimentation Rate
  • C-Reactive Protein
  • Serum a -1 Antitrypsin
  • Fecal Calprotectin
  • Fecal Lactoferrin
  • Fecal Pyruvate Kinase
  • Laboratory Tests for the Evaluation of Systemic Adverse Sequalae of Pouchitis and Pouch Surgery
  • Hemoglobin and Hematocrit
  • Liver Function Tests
  • Celiac Serology
  • Blood and Urine Chemistry Related to Bone Metabolism
  • Microbiology Evaluation
  • Stool Bacterial Culture and Sensitivity
  • Stool C. difficile
  • Summary and Recommendations
  • References
  • Chapter 20 IBD Serology in Pouch Disorders
  • Introduction
  • IBD-Specific Serology Tests
  • IBD Serology After Restorative Proctocolectomy
  • Risk Assessment for the Development of Pouchitis
  • Perinuclear Antineutrophil Cytoplasmic Antibody
  • Anti- Saccharomyces cerevisiae Antibody
  • Anti-CBir-1
  • Other IBD-Associated Antibodies
  • Risk Assessment for Development of De Novo Crohn'S Disease of the Pouch
  • Prediction of Treatment Response
  • Summary and Recommendations
  • References
  • Chapter 21 Diagnosis, Differential Diagnosis, and Prognosis of Crohn's Disease the Pouch
  • Introduction
  • Terminology
  • Frequency
  • Risk Factors and Pathogenesis
  • Clinical Presentations
  • Diagnosis and Differential Diagnosis
  • Clinical Presentations
  • Endoscopic Evaluation
  • Histology
  • Laboratory Evaluation
  • Abdominal and Pelvic Imaging
  • Classification
  • Inflammatory CD of the Pouch
  • Fibrostenotic CD of the Pouch
  • Fistulizing CD of the Pouch
  • Pouch-Vaginal Fistula
  • Prognosis
  • Summary and Recommendations
  • References
  • Chapter 22 Manometry Evaluation in Ileal Pouch Disorders
  • Introduction
  • Instrument and Manometric Variables
  • Indications for Manometry
  • Preoperative Evaluation
  • Postoperative Changes
  • Diagnosis and Differential Diagnosis of Functional Pouch Disorders
  • Evaluation of Response to Treatment
  • Hyperactive Pouches
  • Irritable Pouch Syndrome
  • Sawtooth Contractions
  • Hypoactive Pouch
  • Megapouch
  • Floppy Pouch Complex
  • Dyssyngergic Defecation
  • Summary and Recommmendation
  • Disclosure
  • References
  • Chapter 23 Extraintestinal Manifestations and Concurrent Autoimmune Disorders in Pouch Patients
  • Introduction
  • Extraintetinal Manifestations in Patients With Ileal Pouches
  • Primary Sclerosing Cholangitis
  • Autoantibodies and Pouchitis Autoantibodies
  • Autoimmune Disorders and Pouchitis
  • Immunoglobulin G4 and Pouchitis
  • Summary and Conclusions
  • References
  • Chapter 24 Dysplasia and Cancer in the Ileal Pouch
  • Introduction
  • Prevalence and Incidence of Pouch Dysplasia
  • Incidence and Prevalence of Pouch Cancer
  • Mucosectomy and Risk of Pouch Neoplasia
  • Risk Factors for Pouch Neoplsia
  • Clinical Presentation of Pouch Neoplasia
  • Endoscopic Assessment of Pouch Neoplasia
  • Histologic Features of Pouch Neoplasia
  • Imaging in Pouch Neoplasia
  • Etiopathgenesis Pouch Neoplasia
  • Surveillance and Detection of Pouch Neoplasia
  • Accuracy of Pouchoscopy
  • Controversy on Routine Surveillance of Pouchoscopy
  • Advanced Technology for Early Detection of Pouch Neoplasia
  • Treatment of Pouch Neoplasia
  • Pouch Cancer
  • High-Grade Dysplasia
  • Low-Grade Dysplasia
  • Prognosis of Pouch Cancer
  • Summary and Recommendations
  • References
  • Chapter 25 Diagnosis and Management of Cuffitis
  • Introduction
  • Prevalence
  • Etiology and Risk Factors
  • Cuffitis and Neoplasia
  • Diagnosis and Classification
  • Clinical Presentation
  • Endoscopic Evaluation
  • Histologic Evaluation
  • Imaging
  • Examination Under Anesthesia
  • Diagnostic Criteria
  • Grading of Disease Activity: The Cuffitis Activity Index
  • Classification and Disease Course of Cuffitis
  • Differential Diagnosis
  • Irritable Pouch Syndrome
  • Pouchitis
  • Foreign Body Injury
  • Prolapse
  • Cuff Polyps
  • CD of the Pouch
  • Cuffitis in the Diverted Pouch
  • Treatment
  • Mesalamines
  • Corticosteroids
  • Biological Therapy
  • Pelvic Physical Therapy
  • Surgical Treatment
  • Other Treatment Modalities
  • Summary and Recommendations
  • Financial Disclosure
  • References
  • Chapter 26 Pouch-Vaginal Fistula: Management
  • Introduction
  • Evaluation and Diagnosis
  • What Is the Ideal Treatment?
  • Conservative Treatment
  • Seton Placement
  • Fistula Plugs
  • Transanal Pouch Advancement Flap
  • Transvaginal Repair
  • Interposition Flaps
  • Transabdominal-Transanal-Perineal Approach
  • Pouch Excision
  • Pouch Failure and Quality of Life
  • Conclusion and Recommendations
  • References
  • Chapter 27 Maintenance of a Healthy Pouch
  • Introduction
  • Types of Ileal Pouch
  • Bowel Frequency and Consistency in Patients With Healthy Pouches
  • Red Flags Suggestive of Diseased Pouch Conditions
  • The Pouch Diet
  • Diet for Nutrition
  • Diet for the Control of Pouch-Related Symptoms
  • Diet for the Prevention of Pouchitis
  • Smoking, Alcohol, Caffeine, and Tea
  • Bathroom Habit
  • Travel
  • Weight Gain and Pouch Health
  • Exercise and Physical Activity
  • Sexuality and Fertility Concerns
  • Physical and Psychosocial Health
  • Physical Health
  • Psychosocial Health
  • Disability
  • General Health Maintenance and Role of PCPs
  • Multidisciplinary Team for the Care
  • Prebiotics, Probiotics, and Fecal Microbiota Transplantation
  • Prebiotics
  • Probiotics
  • Fecal Microbiota Transplantation
  • Pain Issue in Pouch Patients
  • Etiology of Pain
  • Medial Management of Pain
  • Behavioral and Physical Therapy of Pain
  • Anesthesiology Pain Management
  • Disease Monitoring Strategies
  • Concerns on Cancer Risk
  • Common Causes of Pouch Failure
  • Summary and Recommendations
  • References
  • Chapter 28 Quality of Life in Patients With Healthy and Diseased Ileal Pouch
  • Introduction
  • Definition of QoL
  • QoL Instruments in IBD and Ileal Pouches
  • QoL in UC
  • QoL in Patients With Healthy Pouches
  • QoL in Patients With Diseased Pouches
  • Early Postoperative Complications
  • Late Postoperative Complications
  • QoL as a Treatment Outcome for Ileal Pouch Disorders
  • Summary and Recommendations
  • Disclosure
  • References
  • Chapter 29 Medical Treatment of Pouchitis
  • Introduction
  • Classification of Pouchitis for Stratification of Treatment Plan
  • Primary and Secondary Prophylaxis of Pouchitis
  • Dietary Modifications
  • Probiotic Prophylaxis
  • Antibiotic Prophylaxis
  • 5-Aminosalicylate Prophylaxis
  • Treatment of Microbiota-Associated Pouchitis
  • Antibiotics
  • Probiotic Therapy
  • Treatment of C. difficile Pouchitis
  • Fecal Microbiota Transplant
  • Treatment of Immune-Mediated Pouchitis
  • Aminosalicylates and Mesalamines
  • Corticosteroids
  • Biological Agents
  • Treatment of Ischemia-Associated Pouchitis
  • Miscellaneous Therapies
  • Summary and Recommendations
  • References
  • Chapter 30 Medical Therapy for Crohn's Disease the Pouch
  • Introduction
  • Phenotypes and Treatment Strategies
  • Antibiotics
  • Mesalamines
  • Corticosteroids
  • Immunomodulators
  • Biological Agents
  • Monitor Treatment Response and Adverse Events
  • Other Therapeutic Modalities
  • PVF From CD
  • Disease Course and Prognosis
  • Summary and Recommendations
  • References
  • Chapter 31 Floppy Pouch Complex
  • Introduction
  • Pouch Prolapse and Pouchocele
  • Clinical Presentation
  • Endoscopy
  • Histology
  • Imaging
  • Manometry
  • Treatment
  • Afferent Limb Syndrome
  • Clinical Presentation
  • Endoscopy
  • Imaging
  • Manometry
  • Treatment
  • Efferent Limb Syndrome
  • Clinical Presentation
  • Endoscopy
  • Imaging
  • Manometry
  • Treatment
  • Folded Pouch and Pouchocele
  • Floppy Pouch Complex
  • Summary and Recommendation
  • Disclosure
  • References
  • Chapter 32 Medical, Endoscopic, and Surgical Treatment of Pouch Strictures
  • Introduction
  • Frequency of Stricture
  • Etiology and Risk Factors of Stricture
  • Diagnosis of Stricture
  • Clinical Presentations
  • Pouch Endoscopy
  • Imaging
  • Differential Diagnosis
  • Classification of Stricture
  • Medical Treatment of Stricture
  • Endoscopic Treatment of Stricture
  • Principles of Endoscopic Therapy
  • Endoscopic Balloon Dilation
  • Endoscopic Stricturotomy
  • Stent Placement
  • Surgical Treatment of Stricture
  • Bougie Dilation
  • Resection and Anastomosis
  • Stricturoplasty
  • Fecal Diversion
  • Pouch Redo
  • Summary and Recommendations
  • Disclosure
  • References
  • Chapter 33 Endoscopic Therapy for Acute and Chronic Anastomotic Leaks
  • Introduction
  • Etiology and Classification of Pouch Leak
  • Diagnosis of Pouch Leak
  • Clinical Presentation
  • Endoscopy
  • Imaging
  • Examination Under Anesthesia
  • Endoscopic Therapy for Acute Leaks
  • Endoscopic Treatment of Chronic Leaks: Presacral Sinus
  • Natural History of Pouch Sinus
  • Surgical Treatment of Pouch Sinus
  • Endoscopic Sinusotomy: Principles and Techniques
  • Endoscopic Sinusotomy: Outcomes
  • Endoscopic Therapy for Chronic Leak: Leak at the Tip of the "J"
  • Endoscopic Therapy for PVF
  • Summary and Recommendations
  • Acknowledgment
  • Disclosure
  • References
  • Chapter 34 Endoscopic Therapy of Pouch Fistula, Septum, and Abscess
  • Introduction
  • Principles of Endoscopic Treatment of Pouch Fistula and Abscess
  • Endoscopic Fistulotomy
  • Endoscopic Septectomy
  • Endoscopic Incision and Drainage of Abscess
  • Incision and Drainage
  • Pigtail Stent
  • Seton and Mushroom Catheter Placement
  • Endoscopic Injection of Fistular Tract
  • Fibrin Glue
  • Plugs
  • Topical Therapy of Stromal Cells or Stem Cells
  • Endoscopic Clipping, Suturing, and Covering of Fistula
  • Endoscopic Clipping
  • Endoscopic Suturing
  • Covering Metal Stent
  • Summary and Recommendations
  • Disclosure
  • References
  • Chapter 35 Endoscopic Management of Pouch Bezoars, Bleeding, Inflammatory Polyps, and Other Miscellaneous Pouch Conditions
  • Introducion
  • Pouch Bezoars
  • Frequency
  • Etiology and Risk Factors
  • Diagnosis
  • Management
  • Pouch Bleeding
  • Frequency
  • Etiology and Risk Factors
  • Diagnosis
  • Management
  • Twisted Pouch
  • Frequency
  • Etiology and Risk Factors
  • Diagnosis
  • Management
  • Inflammatory Pouch Polyps
  • Frequency
  • Etiology and Risk Factors
  • Diagnosis
  • Management
  • Compartmentalized Pouch From Septum or Mucosal Bridge
  • Etiology and Risk Factors
  • Diagnosis
  • Management
  • Summary and Recommendations
  • References
  • Chapter 36 Surgical Management of Crohn Disease of the Ileal Pouch
  • Introduction
  • Principles of Surgical Management
  • Perianal Procedures
  • Resection of Stricture and Strictureplasty
  • Revisionary Ileal Pouch Surgery
  • Conversion of Ileal Pouch Into Continent Ileostomy
  • Fecal Diversion and Pouch Excision
  • Summary and Recommendations
  • References
  • Chapter 37 Salvage and Revision Surgery for the Failed Pouch
  • Introduction
  • Risk Factors for Pouch Failure
  • Pouch Complications and Their Surgical Management
  • Postoperative Pouch Bleeding
  • Pouch-Vaginal Fistula
  • Pouch Sinus
  • Leak From the Tip of the "J" (Figs. 37.2 and 37.3)
  • Pouch Prolapse
  • Pouchitis and Cuffitis
  • Pouch Obstruction and Outlet Dysfunction
  • CD of the Pouch
  • Pelvic Sepsis (Fig. 37.1)
  • Perineal Procedures for Fistulae
  • Endoanal and Endovaginal Advancement Flaps (Fig. 37.4)
  • Fibrin Glue
  • Anal Fistula Plug
  • Pouch Advancement
  • The LIFT
  • Abdominal Approaches for Pouch Revision, Repair, and Redo
  • Redo IPAA
  • The Koch Pouch or Continent Ileostomy
  • Pouch In Situ
  • Outcomes for Salvage and Revisional Surgery
  • Summary and Conclusions
  • References
  • Chapter 38 Kock Pouch, Barnett Continent Intestinal Reservoir, and Diverted Pouch
  • Introduction
  • Kock Pouch
  • Indications and Contraindications
  • Disorders of Nipple Valve of the Kock Pouch
  • Pouchitis of the Kock Pouch
  • CD of the Kock Pouch
  • Pouch Bezoars
  • Risk of Pouch Neoplasia
  • Long-Term Prognosis of Patients With Kock Pouches
  • Barnett Continent Intestinal Researvoir
  • Diverted Pouch
  • Diversion Pouchitis
  • Distal Pouch Stricture
  • Neoplasia in Diverted Pouch
  • Surgical Excision of Diseased Diverted Pouch
  • Summary and Recommendations
  • References
  • Chapter 39 Liver Surgery in Patients With Inflammatory Bowel Disease
  • Introduction
  • Liver Transplantation for PSC
  • Biliary Reconstruction
  • Recurrence of PSC After Liver Transplantation
  • IBD and Liver Transplantation for PSC
  • Safety of Restorative Colectomy and Ileal Pouch Surgery in Patients With Liver Transplantation
  • Impact of Liver Transplantation on Disease Course of IBD
  • Impact of Liver Transplantation on Disease Course of Ileal Pouch
  • Impact of IBD and Ileal Pouch on the Outcome of Liver Transplantation
  • Impact of Treatment for IBD on LT Outcomes
  • Liver Surgery for CCA
  • Liver Transplantation and Colitis-Associated Neoplasia
  • Summary and Recommendations
  • References
  • Chapter 40 Functional Disorders of the Ileal Pouch
  • Introduction
  • Diagnosis of Functional Pouch Disorders
  • Clinical Presentations
  • Endoscopy and Histology
  • Evaluation of Small-Intestinal Bacterial Overgrowth
  • Laboratory Tests
  • Imaging
  • Barostat and Manometry
  • Classification of Functional Pouch Disorders
  • Etiopathogenesis and Risk Factors
  • Psychological Factors
  • Microbiota
  • Visceral Hypersensitivity and Dysmotility
  • Cellular and Molecular Factors
  • Management
  • Cognitive Behavioral Therapy
  • Systemic Pharmaceutical Therapy
  • Topical Pharmaceutical Therapy
  • Pelvic Physical Therapy
  • Anesthesiology Pain Management
  • Surgery
  • Summary and Recommendations
  • Acknowledgment
  • References
  • Chapter 41 Male Issues of the Ileal Pouch
  • Introductıon
  • Gender and Pouch Dysfunction
  • Sexual Dysfunction and Colectomy
  • Benign Urological Diseases in Pouch Patients
  • Urological Malignancy in Patients With the Pouch
  • Summary and Recommendations
  • Acknowledgment
  • Conflicts of Interest
  • References
  • Chapter 42 Women's Health Issues and Ileal Pouch Surgery
  • Introduction
  • Menstrual Cycle
  • Sexual Health
  • Prevalence of Sexual Dysfunction
  • Mechanisms of Sexual Dysfunction
  • Impact of Bowel Behavior on Sexual Function
  • Postsurgical Changes and Sexual Dysfunction
  • Limitations of Studies in Sexual Dysfunction in Female Pouch Patients
  • Fertility
  • Frequency of Fertility and Fecundity
  • Mechanisms for Infertility
  • Prevention and Management of Infertility
  • Pregnancy
  • Colon Surgery During Pregnancy
  • Pouch Function During Pregnancy
  • Child Birth
  • Special Situation in Women With Ileal Pouch Dysfunction
  • Pouch-Vaginal Fistula
  • Floppy Pouch Complex
  • Trapped Ovary Syndrome and Pelvic Fluid Collection
  • Pelvic Radiation and Pouch Function
  • Summary and Recommendations
  • Conflicts of Interest
  • References
  • Chapter 43 Novel Approaches for Pouchitis and Colitis With or Without Diversion
  • Introduction
  • Probiotics
  • Clinical Utility of Probiotics
  • Mechanisms of Action of Probiotics
  • Fibers
  • Beneficial Effects of Dietary Fibers on GI Health and General Health
  • Mechanisms of Action of Dietary Fibers
  • Short-Chain Fatty Acids
  • Beneficial Effects of SCFAs
  • Mechanisms of Actions of SCFAs
  • Mixture of Probiotics and Fiber Supplements And Therapeutic Mechanisms
  • Production of SCFAs In Vitro
  • Potential Therapeutic Applications of In Vivo Produced SCFAs
  • Summary and Recommendations
  • References
  • Index
  • Back Cover

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